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84 similar compounds to monomer 22038

Compile data set for download or QSAR
Wt: 436.6
BDBM50045877
Purchase
Wt: 352.4
BDBM50045887
Wt: 352.4
BDBM50045888
Wt: 471.0
BDBM50045892
Wt: 366.4
BDBM50045859
Wt: 408.5
BDBM50045863
Wt: 380.4
BDBM50045867
Wt: 352.4
BDBM50045871
Wt: 432.5
BDBM50143220
Wt: 348.4
BDBM50143221
Wt: 346.4
BDBM50143222
Wt: 348.4
BDBM50143223
Wt: 362.4
BDBM50143224
Wt: 445.3
BDBM50143225
Wt: 404.5
BDBM50143226
Displayed 1 to 15 (of 84 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 88 hits for monomerid = 50045877,50045887,50045888,50045892,50045859,50045863,50045867,50045871,50143220,50143221,50143222,50143223,50143224,50143225,50143226   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143220
PNG
(CHEMBL294625 | N,N-Dihexyl-2-oxo-2-(2-phenyl-1H-in...)
Show SMILES CCCCCCN(CCCCCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C28H36N2O2/c1-3-5-7-14-20-30(21-15-8-6-4-2)28(32)27(31)25-23-18-12-13-19-24(23)29-26(25)22-16-10-9-11-17-22/h9-13,16-19,29H,3-8,14-15,20-21H2,1-2H3
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1.40n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by ChEMBL


Assay Description
Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membrane


J Med Chem 54: 366-73 (2011)


Article DOI: 10.1021/jm101230g
BindingDB Entry DOI: 10.7270/Q2ZC83T4
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143220
PNG
(CHEMBL294625 | N,N-Dihexyl-2-oxo-2-(2-phenyl-1H-in...)
Show SMILES CCCCCCN(CCCCCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C28H36N2O2/c1-3-5-7-14-20-30(21-15-8-6-4-2)28(32)27(31)25-23-18-12-13-19-24(23)29-26(25)22-16-10-9-11-17-22/h9-13,16-19,29H,3-8,14-15,20-21H2,1-2H3
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1.40n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from translocator protein in rat kidney mitochondrial membrane


J Med Chem 51: 5798-806 (2008)


Article DOI: 10.1021/jm8003224
BindingDB Entry DOI: 10.7270/Q2GF0VD5
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143220
PNG
(CHEMBL294625 | N,N-Dihexyl-2-oxo-2-(2-phenyl-1H-in...)
Show SMILES CCCCCCN(CCCCCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C28H36N2O2/c1-3-5-7-14-20-30(21-15-8-6-4-2)28(32)27(31)25-23-18-12-13-19-24(23)29-26(25)22-16-10-9-11-17-22/h9-13,16-19,29H,3-8,14-15,20-21H2,1-2H3
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1.40n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Binding affinity to peripheral benzodiazepine receptors using [3H]-PK11195 radioligand in rat kidney mitochondrial membrane


J Med Chem 47: 1852-5 (2004)


Article DOI: 10.1021/jm030973k
BindingDB Entry DOI: 10.7270/Q2WQ04K6
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143225
PNG
(CHEMBL300762 | N,N-Dibutyl-2-[5-chloro-2-(4-chloro...)
Show SMILES CCCCN(CCCC)C(=O)C(=O)c1c([nH]c2ccc(Cl)cc12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26Cl2N2O2/c1-3-5-13-28(14-6-4-2)24(30)23(29)21-19-15-18(26)11-12-20(19)27-22(21)16-7-9-17(25)10-8-16/h7-12,15,27H,3-6,13-14H2,1-2H3
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1.90n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Binding affinity to peripheral benzodiazepine receptors using [3H]-PK11195 radioligand in rat kidney mitochondrial membrane


J Med Chem 47: 1852-5 (2004)


Article DOI: 10.1021/jm030973k
BindingDB Entry DOI: 10.7270/Q2WQ04K6
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045892
PNG
(2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccc(Cl)cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H36ClFN2O/c1-3-5-7-9-17-32(18-10-8-6-4-2)27(33)20-25-24-19-22(29)13-16-26(24)31-28(25)21-11-14-23(30)15-12-21/h11-16,19,31H,3-10,17-18,20H2,1-2H3
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2.30n/an/an/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Translocator protein


(Homo sapiens (Human))
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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3.30n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of TSPO (unknown origin)


Eur J Med Chem 125: 1172-1192 (2017)


Article DOI: 10.1016/j.ejmech.2016.11.017
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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4.40n/an/an/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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5n/an/an/an/an/an/an/an/a



Brain and Mind Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat cortex


J Med Chem 52: 581-92 (2009)


Article DOI: 10.1021/jm8011678
BindingDB Entry DOI: 10.7270/Q2222VP0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143224
PNG
(2-Oxo-N,N-dipropyl-2-(2-p-tolyl-1H-indol-3-yl)-ace...)
Show SMILES CCCN(CCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccc(C)cc1
Show InChI InChI=1S/C23H26N2O2/c1-4-14-25(15-5-2)23(27)22(26)20-18-8-6-7-9-19(18)24-21(20)17-12-10-16(3)11-13-17/h6-13,24H,4-5,14-15H2,1-3H3
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5.5n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Binding affinity to peripheral benzodiazepine receptors using [3H]-PK11195 radioligand in rat kidney mitochondrial membrane


J Med Chem 47: 1852-5 (2004)


Article DOI: 10.1021/jm030973k
BindingDB Entry DOI: 10.7270/Q2WQ04K6
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143223
PNG
(2-Oxo-2-(2-phenyl-1H-indol-3-yl)-N,N-dipropyl-acet...)
Show SMILES CCCN(CCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H24N2O2/c1-3-14-24(15-4-2)22(26)21(25)19-17-12-8-9-13-18(17)23-20(19)16-10-6-5-7-11-16/h5-13,23H,3-4,14-15H2,1-2H3
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12.2n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by ChEMBL


Assay Description
Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membrane


J Med Chem 54: 366-73 (2011)


Article DOI: 10.1021/jm101230g
BindingDB Entry DOI: 10.7270/Q2ZC83T4
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143223
PNG
(2-Oxo-2-(2-phenyl-1H-indol-3-yl)-N,N-dipropyl-acet...)
Show SMILES CCCN(CCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H24N2O2/c1-3-14-24(15-4-2)22(26)21(25)19-17-12-8-9-13-18(17)23-20(19)16-10-6-5-7-11-16/h5-13,23H,3-4,14-15H2,1-2H3
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12.2n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Binding affinity to peripheral benzodiazepine receptors using [3H]-PK11195 radioligand in rat kidney mitochondrial membrane


J Med Chem 47: 1852-5 (2004)


Article DOI: 10.1021/jm030973k
BindingDB Entry DOI: 10.7270/Q2WQ04K6
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143223
PNG
(2-Oxo-2-(2-phenyl-1H-indol-3-yl)-N,N-dipropyl-acet...)
Show SMILES CCCN(CCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H24N2O2/c1-3-14-24(15-4-2)22(26)21(25)19-17-12-8-9-13-18(17)23-20(19)16-10-6-5-7-11-16/h5-13,23H,3-4,14-15H2,1-2H3
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12.2n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from translocator protein in rat kidney mitochondrial membrane


J Med Chem 51: 5798-806 (2008)


Article DOI: 10.1021/jm8003224
BindingDB Entry DOI: 10.7270/Q2GF0VD5
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045863
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dipentyl...)
Show SMILES CCCCCN(CCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C26H33FN2O/c1-3-5-9-17-29(18-10-6-4-2)25(30)19-23-22-11-7-8-12-24(22)28-26(23)20-13-15-21(27)16-14-20/h7-8,11-16,28H,3-6,9-10,17-19H2,1-2H3
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15n/an/an/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143226
PNG
(2-Oxo-N,N-dipentyl-2-(2-phenyl-1H-indol-3-yl)-acet...)
Show SMILES CCCCCN(CCCCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C26H32N2O2/c1-3-5-12-18-28(19-13-6-4-2)26(30)25(29)23-21-16-10-11-17-22(21)27-24(23)20-14-8-7-9-15-20/h7-11,14-17,27H,3-6,12-13,18-19H2,1-2H3
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16n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Binding affinity to peripheral benzodiazepine receptors using [3H]-PK11195 radioligand in rat kidney mitochondrial membrane


J Med Chem 47: 1852-5 (2004)


Article DOI: 10.1021/jm030973k
BindingDB Entry DOI: 10.7270/Q2WQ04K6
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143222
PNG
(1-Azepan-1-yl-2-(2-phenyl-1H-indol-3-yl)-ethane-1,...)
Show SMILES O=C(N1CCCCCC1)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H22N2O2/c25-21(22(26)24-14-8-1-2-9-15-24)19-17-12-6-7-13-18(17)23-20(19)16-10-4-3-5-11-16/h3-7,10-13,23H,1-2,8-9,14-15H2
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33n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Binding affinity to peripheral benzodiazepine receptors using [3H]-PK11195 radioligand in rat kidney mitochondrial membrane


J Med Chem 47: 1852-5 (2004)


Article DOI: 10.1021/jm030973k
BindingDB Entry DOI: 10.7270/Q2WQ04K6
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045867
PNG
(CHEMBL316711 | N,N-Dibutyl-2-[2-(4-fluoro-phenyl)-...)
Show SMILES CCCCN(CCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C24H29FN2O/c1-3-5-15-27(16-6-4-2)23(28)17-21-20-9-7-8-10-22(20)26-24(21)18-11-13-19(25)14-12-18/h7-14,26H,3-6,15-17H2,1-2H3
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45n/an/an/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045887
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dipropyl...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C22H25FN2O/c1-3-13-25(14-4-2)21(26)15-19-18-7-5-6-8-20(18)24-22(19)16-9-11-17(23)12-10-16/h5-12,24H,3-4,13-15H2,1-2H3
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100n/an/an/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50143221
PNG
(CHEMBL301836 | N,N-Diisopropyl-2-oxo-2-(2-phenyl-1...)
Show SMILES CC(C)N(C(C)C)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C22H24N2O2/c1-14(2)24(15(3)4)22(26)21(25)19-17-12-8-9-13-18(17)23-20(19)16-10-6-5-7-11-16/h5-15,23H,1-4H3
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103n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Binding affinity to peripheral benzodiazepine receptors using [3H]-PK11195 radioligand in rat kidney mitochondrial membrane


J Med Chem 47: 1852-5 (2004)


Article DOI: 10.1021/jm030973k
BindingDB Entry DOI: 10.7270/Q2WQ04K6
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045859
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N-hexyl-N-me...)
Show SMILES CCCCCCN(C)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C23H27FN2O/c1-3-4-5-8-15-26(2)22(27)16-20-19-9-6-7-10-21(19)25-23(20)17-11-13-18(24)14-12-17/h6-7,9-14,25H,3-5,8,15-16H2,1-2H3
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135n/an/an/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045871
PNG
(2-(7-Fluoro-2-phenyl-1H-indol-3-yl)-N,N-dipropyl-a...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2c(F)cccc12)-c1ccccc1
Show InChI InChI=1S/C22H25FN2O/c1-3-13-25(14-4-2)20(26)15-18-17-11-8-12-19(23)22(17)24-21(18)16-9-6-5-7-10-16/h5-12,24H,3-4,13-15H2,1-2H3
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211n/an/an/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045888
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N-hexyl-acet...)
Show SMILES CCCCCCNC(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C22H25FN2O/c1-2-3-4-7-14-24-21(26)15-19-18-8-5-6-9-20(18)25-22(19)16-10-12-17(23)13-11-16/h5-6,8-13,25H,2-4,7,14-15H2,1H3,(H,24,26)
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323n/an/an/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50045871
PNG
(2-(7-Fluoro-2-phenyl-1H-indol-3-yl)-N,N-dipropyl-a...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2c(F)cccc12)-c1ccccc1
Show InChI InChI=1S/C22H25FN2O/c1-3-13-25(14-4-2)20(26)15-18-17-11-8-12-19(23)22(17)24-21(18)16-9-6-5-7-10-16/h5-12,24H,3-4,13-15H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50045867
PNG
(CHEMBL316711 | N,N-Dibutyl-2-[2-(4-fluoro-phenyl)-...)
Show SMILES CCCCN(CCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C24H29FN2O/c1-3-5-15-27(16-6-4-2)23(28)17-21-20-9-7-8-10-22(20)26-24(21)18-11-13-19(25)14-12-18/h7-14,26H,3-6,15-17H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50045859
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N-hexyl-N-me...)
Show SMILES CCCCCCN(C)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C23H27FN2O/c1-3-4-5-8-15-26(2)22(27)16-20-19-9-6-7-10-21(19)25-23(20)17-11-13-18(24)14-12-17/h6-7,9-14,25H,3-5,8,15-16H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50045888
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N-hexyl-acet...)
Show SMILES CCCCCCNC(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C22H25FN2O/c1-2-3-4-7-14-24-21(26)15-19-18-8-5-6-9-20(18)25-22(19)16-10-12-17(23)13-11-16/h5-6,8-13,25H,2-4,7,14-15H2,1H3,(H,24,26)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50045887
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dipropyl...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C22H25FN2O/c1-3-13-25(14-4-2)21(26)15-19-18-7-5-6-8-20(18)24-22(19)16-9-11-17(23)12-10-16/h5-12,24H,3-4,13-15H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50045887
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dipropyl...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C22H25FN2O/c1-3-13-25(14-4-2)21(26)15-19-18-7-5-6-8-20(18)24-22(19)16-9-11-17(23)12-10-16/h5-12,24H,3-4,13-15H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50045859
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N-hexyl-N-me...)
Show SMILES CCCCCCN(C)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C23H27FN2O/c1-3-4-5-8-15-26(2)22(27)16-20-19-9-6-7-10-21(19)25-23(20)17-11-13-18(24)14-12-17/h6-7,9-14,25H,3-5,8,15-16H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50045892
PNG
(2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccc(Cl)cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H36ClFN2O/c1-3-5-7-9-17-32(18-10-8-6-4-2)27(33)20-25-24-19-22(29)13-16-26(24)31-28(25)21-11-14-23(30)15-12-21/h11-16,19,31H,3-10,17-18,20H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50045867
PNG
(CHEMBL316711 | N,N-Dibutyl-2-[2-(4-fluoro-phenyl)-...)
Show SMILES CCCCN(CCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C24H29FN2O/c1-3-5-15-27(16-6-4-2)23(28)17-21-20-9-7-8-10-22(20)26-24(21)18-11-13-19(25)14-12-18/h7-14,26H,3-6,15-17H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50045871
PNG
(2-(7-Fluoro-2-phenyl-1H-indol-3-yl)-N,N-dipropyl-a...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2c(F)cccc12)-c1ccccc1
Show InChI InChI=1S/C22H25FN2O/c1-3-13-25(14-4-2)20(26)15-18-17-11-8-12-19(23)22(17)24-21(18)16-9-6-5-7-10-16/h5-12,24H,3-4,13-15H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50045863
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dipentyl...)
Show SMILES CCCCCN(CCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C26H33FN2O/c1-3-5-9-17-29(18-10-6-4-2)25(30)19-23-22-11-7-8-12-24(22)28-26(23)20-13-15-21(27)16-14-20/h7-8,11-16,28H,3-6,9-10,17-19H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50045888
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N-hexyl-acet...)
Show SMILES CCCCCCNC(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C22H25FN2O/c1-2-3-4-7-14-24-21(26)15-19-18-8-5-6-9-20(18)25-22(19)16-10-12-17(23)13-11-16/h5-6,8-13,25H,2-4,7,14-15H2,1H3,(H,24,26)
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
CCKBR


(RAT)
BDBM50045863
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dipentyl...)
Show SMILES CCCCCN(CCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C26H33FN2O/c1-3-5-9-17-29(18-10-6-4-2)25(30)19-23-22-11-7-8-12-24(22)28-26(23)20-13-15-21(27)16-14-20/h7-8,11-16,28H,3-6,9-10,17-19H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50045892
PNG
(2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccc(Cl)cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H36ClFN2O/c1-3-5-7-9-17-32(18-10-8-6-4-2)27(33)20-25-24-19-22(29)13-16-26(24)31-28(25)21-11-14-23(30)15-12-21/h11-16,19,31H,3-10,17-18,20H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Peripheral-type benzodiazepine receptor


(Mus musculus)
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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n/an/a 10n/an/an/an/an/an/a



Pharmacia & Upjohn

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 binding from peripheral benzodiazepine receptor in MA-10 mouse tumor Leydig cells


J Med Chem 39: 2435-7 (1996)


Article DOI: 10.1021/jm960084f
BindingDB Entry DOI: 10.7270/Q2H1314Z
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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Pharmacia & Upjohn

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 binding from peripheral benzodiazepine receptor in C6 rat glioma cell line


J Med Chem 39: 2435-7 (1996)


Article DOI: 10.1021/jm960084f
BindingDB Entry DOI: 10.7270/Q2H1314Z
More data for this
Ligand-Target Pair
Translocator protein


(Homo sapiens (Human))
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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n/an/an/a 4n/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Binding affinity to human PBR


Bioorg Med Chem 16: 6145-55 (2008)


Article DOI: 10.1016/j.bmc.2008.04.046
BindingDB Entry DOI: 10.7270/Q26Q1Z4G
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)
BDBM50045892
PNG
(2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccc(Cl)cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H36ClFN2O/c1-3-5-7-9-17-32(18-10-8-6-4-2)27(33)20-25-24-19-22(29)13-16-26(24)31-28(25)21-11-14-23(30)15-12-21/h11-16,19,31H,3-10,17-18,20H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)
BDBM50045867
PNG
(CHEMBL316711 | N,N-Dibutyl-2-[2-(4-fluoro-phenyl)-...)
Show SMILES CCCCN(CCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C24H29FN2O/c1-3-5-15-27(16-6-4-2)23(28)17-21-20-9-7-8-10-22(20)26-24(21)18-11-13-19(25)14-12-18/h7-14,26H,3-6,15-17H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50045892
PNG
(2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccc(Cl)cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H36ClFN2O/c1-3-5-7-9-17-32(18-10-8-6-4-2)27(33)20-25-24-19-22(29)13-16-26(24)31-28(25)21-11-14-23(30)15-12-21/h11-16,19,31H,3-10,17-18,20H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50045867
PNG
(CHEMBL316711 | N,N-Dibutyl-2-[2-(4-fluoro-phenyl)-...)
Show SMILES CCCCN(CCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C24H29FN2O/c1-3-5-15-27(16-6-4-2)23(28)17-21-20-9-7-8-10-22(20)26-24(21)18-11-13-19(25)14-12-18/h7-14,26H,3-6,15-17H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50045871
PNG
(2-(7-Fluoro-2-phenyl-1H-indol-3-yl)-N,N-dipropyl-a...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2c(F)cccc12)-c1ccccc1
Show InChI InChI=1S/C22H25FN2O/c1-3-13-25(14-4-2)20(26)15-18-17-11-8-12-19(23)22(17)24-21(18)16-9-6-5-7-10-16/h5-12,24H,3-4,13-15H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (Rat)-RAT-NEONATAL RAT-Rattus no...)
BDBM50045892
PNG
(2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccc(Cl)cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H36ClFN2O/c1-3-5-7-9-17-32(18-10-8-6-4-2)27(33)20-25-24-19-22(29)13-16-26(24)31-28(25)21-11-14-23(30)15-12-21/h11-16,19,31H,3-10,17-18,20H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (Rat)-RAT-NEONATAL RAT-Rattus no...)
BDBM50045888
PNG
(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N-hexyl-acet...)
Show SMILES CCCCCCNC(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C22H25FN2O/c1-2-3-4-7-14-24-21(26)15-19-18-8-5-6-9-20(18)25-22(19)16-10-12-17(23)13-11-16/h5-6,8-13,25H,2-4,7,14-15H2,1H3,(H,24,26)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (Rat)-RAT-NEONATAL RAT-Rattus no...)
BDBM50045867
PNG
(CHEMBL316711 | N,N-Dibutyl-2-[2-(4-fluoro-phenyl)-...)
Show SMILES CCCCN(CCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C24H29FN2O/c1-3-5-15-27(16-6-4-2)23(28)17-21-20-9-7-8-10-22(20)26-24(21)18-11-13-19(25)14-12-18/h7-14,26H,3-6,15-17H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)
BDBM50045871
PNG
(2-(7-Fluoro-2-phenyl-1H-indol-3-yl)-N,N-dipropyl-a...)
Show SMILES CCCN(CCC)C(=O)Cc1c([nH]c2c(F)cccc12)-c1ccccc1
Show InChI InChI=1S/C22H25FN2O/c1-3-13-25(14-4-2)20(26)15-18-17-11-8-12-19(23)22(17)24-21(18)16-9-6-5-7-10-16/h5-12,24H,3-4,13-15H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]naxolone binding to opiate receptors in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)
BDBM50045877
PNG
(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Mayo Foundation for Medical Education and Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]naxolone binding to opiate receptors in rat brain


J Med Chem 36: 2908-20 (1993)


Article DOI: 10.1021/jm00072a010
BindingDB Entry DOI: 10.7270/Q2C24VGV
More data for this
Ligand-Target Pair
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