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4 similar compounds to monomer 50153089

Wt: 376.4
BDBM50054954
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Wt: 418.3
BDBM50197292

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054954,50197292   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Yersiniabactin biosynthetic protein


(Yersinia pestis)
BDBM50197292
PNG
(CHEMBL3889888)
Show SMILES C[C@H](O)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Show InChI InChI=1S/C13H18N6O8S/c1-5(20)12(23)18-28(24,25)26-2-6-8(21)9(22)13(27-6)19-4-17-7-10(14)15-3-16-11(7)19/h3-6,8-9,13,20-22H,2H2,1H3,(H,18,23)(H2,14,15,16)/t5-,6+,8+,9+,13+/m0/s1
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Weill Cornell Graduate School of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant Yersinia pestis C-terminal His6-tagged HMWP2 cysteine adenylation domain (1 to 1491 residues) expressed in Escherichia coli...


Citation and Details
More data for this
Ligand-Target Pair
PI3-kinase subunit gamma


(Homo sapiens (human))
BDBM50054954
PNG
(CHEMBL1885254)
Show SMILES COc1ccc(cc1OC)C(CC(O)=O)c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H24O7/c1-23-15-7-6-12(8-16(15)24-2)14(11-19(21)22)13-9-17(25-3)20(27-5)18(10-13)26-4/h6-10,14H,11H2,1-5H3,(H,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.07E+6n/an/an/an/an/an/a



The University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrate


Eur J Med Chem 84: 454-65 (2014)

More data for this
Ligand-Target Pair