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10 similar compounds to monomer 50088696

Compile data set for download or QSAR
Wt: 444.6
BDBM50056364
Wt: 535.7
BDBM50056366
Wt: 429.6
BDBM50056369
Wt: 459.6
BDBM50056378
Wt: 485.6
BDBM50056382
Wt: 431.5
BDBM50056384
Wt: 492.6
BDBM50056385
Wt: 471.6
BDBM50088686
Wt: 474.6
BDBM50088687
Wt: 473.6
BDBM50088693

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50056364,50056366,50056369,50056378,50056382,50056384,50056385,50088686,50088687,50088693   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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0.160n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50088686
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc4CCCc4c3c(=O)n2N)CC1
Show InChI InChI=1S/C23H29N5O2S2/c1-30-18-8-3-2-7-17(18)27-13-11-26(12-14-27)10-5-15-31-23-25-21-20(22(29)28(23)24)16-6-4-9-19(16)32-21/h2-3,7-8H,4-6,9-15,24H2,1H3
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0.260n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056384
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sccc3c(=O)n2N)CC1
Show InChI InChI=1S/C20H25N5O2S2/c1-27-17-6-3-2-5-16(17)24-11-9-23(10-12-24)8-4-13-29-20-22-18-15(7-14-28-18)19(26)25(20)21/h2-3,5-7,14H,4,8-13,21H2,1H3
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0.650n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50088693
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES CCCc1cc2c(nc(SCCCN3CCN(CC3)c3ccccc3OC)n(N)c2=O)s1
Show InChI InChI=1S/C23H31N5O2S2/c1-3-7-17-16-18-21(32-17)25-23(28(24)22(18)29)31-15-6-10-26-11-13-27(14-12-26)19-8-4-5-9-20(19)30-2/h4-5,8-9,16H,3,6-7,10-15,24H2,1-2H3
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1.40n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50056384
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sccc3c(=O)n2N)CC1
Show InChI InChI=1S/C20H25N5O2S2/c1-27-17-6-3-2-5-16(17)24-11-9-23(10-12-24)8-4-13-29-20-22-18-15(7-14-28-18)19(26)25(20)21/h2-3,5-7,14H,4,8-13,21H2,1H3
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2.5n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cortex membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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6.30n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cortex membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50088686
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc4CCCc4c3c(=O)n2N)CC1
Show InChI InChI=1S/C23H29N5O2S2/c1-30-18-8-3-2-7-17(18)27-13-11-26(12-14-27)10-5-15-31-23-25-21-20(22(29)28(23)24)16-6-4-9-19(16)32-21/h2-3,7-8H,4-6,9-15,24H2,1H3
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7.40n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cortex membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50088687
PNG
(3-Amino-6-ethyl-2-{3-[4-(2-nitro-phenyl)-piperazin...)
Show SMILES CCc1cc2c(nc(SCCCN3CCN(CC3)c3ccccc3[N+]([O-])=O)n(N)c2=O)s1
Show InChI InChI=1S/C21H26N6O3S2/c1-2-15-14-16-19(32-15)23-21(26(22)20(16)28)31-13-5-8-24-9-11-25(12-10-24)17-6-3-4-7-18(17)27(29)30/h3-4,6-7,14H,2,5,8-13,22H2,1H3
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9.70n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50088693
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES CCCc1cc2c(nc(SCCCN3CCN(CC3)c3ccccc3OC)n(N)c2=O)s1
Show InChI InChI=1S/C23H31N5O2S2/c1-3-7-17-16-18-21(32-17)25-23(28(24)22(18)29)31-15-6-10-26-11-13-27(14-12-26)19-8-4-5-9-20(19)30-2/h4-5,8-9,16H,3,6-7,10-15,24H2,1-2H3
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20n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cortex membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50088687
PNG
(3-Amino-6-ethyl-2-{3-[4-(2-nitro-phenyl)-piperazin...)
Show SMILES CCc1cc2c(nc(SCCCN3CCN(CC3)c3ccccc3[N+]([O-])=O)n(N)c2=O)s1
Show InChI InChI=1S/C21H26N6O3S2/c1-2-15-14-16-19(32-15)23-21(26(22)20(16)28)31-13-5-8-24-9-11-25(12-10-24)17-6-3-4-7-18(17)27(29)30/h3-4,6-7,14H,2,5,8-13,22H2,1H3
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195n/an/an/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cortex membranes


Bioorg Med Chem Lett 10: 1089-92 (2000)


Article DOI: 10.1016/s0960-894x(00)00165-7
BindingDB Entry DOI: 10.7270/Q25D8R2B
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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n/an/a 60n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of the compound against radioligand [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membrane


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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n/an/a 400n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of the compound against radioligand [3H]-SCH-23,390 binding to Dopamine receptor D1 in rat striatal membrane


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056385
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(cc3c(=O)[nH]2)-c2ccccc2)CC1
Show InChI InChI=1S/C26H28N4O2S2/c1-32-22-11-6-5-10-21(22)30-15-13-29(14-16-30)12-7-17-33-26-27-24(31)20-18-23(34-25(20)28-26)19-8-3-2-4-9-19/h2-6,8-11,18H,7,12-17H2,1H3,(H,27,28,31)
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n/an/a 386n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056382
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc4CCCCc4c3c(=O)n2N)CC1
Show InChI InChI=1S/C24H31N5O2S2/c1-31-19-9-4-3-8-18(19)28-14-12-27(13-15-28)11-6-16-32-24-26-22-21(23(30)29(24)25)17-7-2-5-10-20(17)33-22/h3-4,8-9H,2,5-7,10-16,25H2,1H3
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n/an/a 1.30n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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n/an/a 600n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of the compound against radioligand [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in pig cortical mem...


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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n/an/a 700n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of the compound against radioligand [3H]-5-HT binding to 5-hydroxytryptamine 1B receptor in rat striatal membrane


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056384
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sccc3c(=O)n2N)CC1
Show InChI InChI=1S/C20H25N5O2S2/c1-27-17-6-3-2-5-16(17)24-11-9-23(10-12-24)8-4-13-29-20-22-18-15(7-14-28-18)19(26)25(20)21/h2-3,5-7,14H,4,8-13,21H2,1H3
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n/an/a 1.20n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056366
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2Nc2ccccc2)CC1
Show InChI InChI=1S/C28H33N5O2S2/c1-20-21(2)37-26-25(20)27(34)33(30-22-10-5-4-6-11-22)28(29-26)36-19-9-14-31-15-17-32(18-16-31)23-12-7-8-13-24(23)35-3/h4-8,10-13,30H,9,14-19H2,1-3H3
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n/an/a 497n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056369
PNG
(3-Amino-5,6-dimethyl-2-[3-(4-phenyl-piperazin-1-yl...)
Show SMILES Cc1sc2nc(SCCCN3CCN(CC3)c3ccccc3)n(N)c(=O)c2c1C
Show InChI InChI=1S/C21H27N5OS2/c1-15-16(2)29-19-18(15)20(27)26(22)21(23-19)28-14-6-9-24-10-12-25(13-11-24)17-7-4-3-5-8-17/h3-5,7-8H,6,9-14,22H2,1-2H3
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n/an/a 3.30n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056364
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)[nH]2)CC1
Show InChI InChI=1S/C22H28N4O2S2/c1-15-16(2)30-21-19(15)20(27)23-22(24-21)29-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)28-3/h4-5,7-8H,6,9-14H2,1-3H3,(H,23,24,27)
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n/an/a 24n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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n/an/a 300n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of the compound against radioligand [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cortical memb...


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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n/an/a 0.300n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50056378
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1
Show InChI InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3
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n/an/a 800n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of the compound against radioligand [3H]-BRL-43694 binding to 5-hydroxytryptamine 3 receptor in rat cortical membra...


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair