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2 similar compounds to monomer 50071812

Compile data set for download or QSAR
Wt: 378.4
BDBM50071796
Wt: 182.1
BDBM50071808
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50071796,50071808   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50071808
PNG
(CHEMBL490514)
Show SMILES COc1cc(O)c(C(C)=O)c(O)c1
Show InChI InChI=1S/C9H10O4/c1-5(10)9-7(11)3-6(13-2)4-8(9)12/h3-4,11-12H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.00E+5n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair
Dihydroorotate dehydrogenase


(Homo sapiens (Human))
BDBM50071796
PNG
(CHEMBL3410609)
Show SMILES CCOC(=O)c1sc(Nc2ccc3CCCCc3c2)nc1-c1ccccc1
Show InChI InChI=1S/C22H22N2O2S/c1-2-26-21(25)20-19(16-9-4-3-5-10-16)24-22(27-20)23-18-13-12-15-8-6-7-11-17(15)14-18/h3-5,9-10,12-14H,2,6-8,11H2,1H3,(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



East China University of Science and Techology

Curated by ChEMBL


Assay Description
Inhibition of human DHODH using dihydroorotate substrate by DCIP assay


J Med Chem 58: 1123-39 (2015)


Article DOI: 10.1021/jm501127s
BindingDB Entry DOI: 10.7270/Q21C1ZK9
More data for this
Ligand-Target Pair