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15 similar compounds to monomer 50073067

Compile data set for download or QSAR
Wt: 359.4
BDBM50073078
Wt: 342.4
BDBM50073065
Wt: 413.5
BDBM50073066
Wt: 482.5
BDBM50073068
Wt: 436.3
BDBM50073070
Wt: 422.3
BDBM50073071
Wt: 420.2
BDBM50073074
Wt: 425.2
BDBM50073076
Wt: 382.2
BDBM50073077
Wt: 342.8
BDBM50097473
Wt: 323.4
BDBM50097480
Wt: 457.5
BDBM50097485
Wt: 398.4
BDBM50097486
Wt: 428.4
BDBM50097484
Wt: 353.4
BDBM50097483

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50073078,50073065,50073066,50073068,50073070,50073071,50073074,50073076,50073077,50097473,50097480,50097485,50097486,50097484,50097483   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073068
PNG
(CHEMBL3410813)
Show SMILES CCCCCOc1ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c2c1OCCCCC
Show InChI InChI=1S/C28H35FN2O4/c1-3-5-7-17-34-24-14-11-21-19-23(27(32)30-16-15-20-9-12-22(29)13-10-20)28(33)31-25(21)26(24)35-18-8-6-4-2/h9-14,19H,3-8,15-18H2,1-2H3,(H,30,32)(H,31,33)
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0.0260n/an/an/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor (unknown origin)


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073068
PNG
(CHEMBL3410813)
Show SMILES CCCCCOc1ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c2c1OCCCCC
Show InChI InChI=1S/C28H35FN2O4/c1-3-5-7-17-34-24-14-11-21-19-23(27(32)30-16-15-20-9-12-22(29)13-10-20)28(33)31-25(21)26(24)35-18-8-6-4-2/h9-14,19H,3-8,15-18H2,1-2H3,(H,30,32)(H,31,33)
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0.0260n/an/an/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor (unknown origin)


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073066
PNG
(CHEMBL3410811)
Show SMILES CCCCCOc1ccc(cc1OCCCCC)C(=O)NCCc1ccc(O)cc1
Show InChI InChI=1S/C25H35NO4/c1-3-5-7-17-29-23-14-11-21(19-24(23)30-18-8-6-4-2)25(28)26-16-15-20-9-12-22(27)13-10-20/h9-14,19,27H,3-8,15-18H2,1-2H3,(H,26,28)
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0.440n/an/an/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor (unknown origin)


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073066
PNG
(CHEMBL3410811)
Show SMILES CCCCCOc1ccc(cc1OCCCCC)C(=O)NCCc1ccc(O)cc1
Show InChI InChI=1S/C25H35NO4/c1-3-5-7-17-29-23-14-11-21(19-24(23)30-18-8-6-4-2)25(28)26-16-15-20-9-12-22(27)13-10-20/h9-14,19,27H,3-8,15-18H2,1-2H3,(H,26,28)
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0.440n/an/an/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor (unknown origin)


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073065
PNG
(CHEMBL3410810)
Show SMILES CCCCCOc1cc(ccc1OC)C(=O)NCCc1ccncc1
Show InChI InChI=1S/C20H26N2O3/c1-3-4-5-14-25-19-15-17(6-7-18(19)24-2)20(23)22-13-10-16-8-11-21-12-9-16/h6-9,11-12,15H,3-5,10,13-14H2,1-2H3,(H,22,23)
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73n/an/an/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor (unknown origin)


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073065
PNG
(CHEMBL3410810)
Show SMILES CCCCCOc1cc(ccc1OC)C(=O)NCCc1ccncc1
Show InChI InChI=1S/C20H26N2O3/c1-3-4-5-14-25-19-15-17(6-7-18(19)24-2)20(23)22-13-10-16-8-11-21-12-9-16/h6-9,11-12,15H,3-5,10,13-14H2,1-2H3,(H,22,23)
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73n/an/an/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor (unknown origin)


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50073071
PNG
(CHEMBL3410715)
Show SMILES CCCCOc1cc(Br)cc2cc(C(=O)NC3CCCCC3)c(=O)oc12
Show InChI InChI=1S/C20H24BrNO4/c1-2-3-9-25-17-12-14(21)10-13-11-16(20(24)26-18(13)17)19(23)22-15-7-5-4-6-8-15/h10-12,15H,2-9H2,1H3,(H,22,23)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB1 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50073070
PNG
(CHEMBL3410716)
Show SMILES CCCCCOc1cc(Br)cc2cc(C(=O)NC3CCCCC3)c(=O)oc12
Show InChI InChI=1S/C21H26BrNO4/c1-2-3-7-10-26-18-13-15(22)11-14-12-17(21(25)27-19(14)18)20(24)23-16-8-5-4-6-9-16/h11-13,16H,2-10H2,1H3,(H,23,24)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB1 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50073074
PNG
(CHEMBL3410718)
Show SMILES Brc1cc(OCC2CC2)c2oc(=O)c(cc2c1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C20H22BrNO4/c21-14-8-13-9-16(19(23)22-15-4-2-1-3-5-15)20(24)26-18(13)17(10-14)25-11-12-6-7-12/h8-10,12,15H,1-7,11H2,(H,22,23)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB1 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Phosphodiesterase 4 and 5 (PDE4 and PDE5)


(Homo sapiens (Human))
BDBM50097486
PNG
(CHEMBL3585873)
Show SMILES FC(F)Oc1ccc(\C=N\OCC(=O)N2CCOCC2)cc1OC1CCCC1
Show InChI InChI=1S/C19H24F2N2O5/c20-19(21)28-16-6-5-14(11-17(16)27-15-3-1-2-4-15)12-22-26-13-18(24)23-7-9-25-10-8-23/h5-6,11-12,15,19H,1-4,7-10,13H2/b22-12+
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n/an/a 1.12E+3n/an/an/an/an/an/a



University of Genoa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate by fluorescence polarization assay


Bioorg Med Chem 23: 3426-35 (2015)


Article DOI: 10.1016/j.bmc.2015.04.027
BindingDB Entry DOI: 10.7270/Q2NC62ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50073077
PNG
(CHEMBL3410720)
Show SMILES CCCCOc1cc(Br)cc2cc(C(=O)NC(C)C)c(=O)oc12
Show InChI InChI=1S/C17H20BrNO4/c1-4-5-6-22-14-9-12(18)7-11-8-13(16(20)19-10(2)3)17(21)23-15(11)14/h7-10H,4-6H2,1-3H3,(H,19,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB1 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50073078
PNG
(CHEMBL3410721)
Show SMILES CCCOc1c(OC)ccc2cc(C(=O)NC3CCCCC3)c(=O)oc12
Show InChI InChI=1S/C20H25NO5/c1-3-11-25-18-16(24-2)10-9-13-12-15(20(23)26-17(13)18)19(22)21-14-7-5-4-6-8-14/h9-10,12,14H,3-8,11H2,1-2H3,(H,21,22)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB1 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50097473
PNG
(CHEMBL3585853)
Show SMILES C[C@H](Cc1ccc(NCc2cc(Cl)ccc2O)cc1)N(C)CC#C
Show InChI InChI=1S/C20H23ClN2O/c1-4-11-23(3)15(2)12-16-5-8-19(9-6-16)22-14-17-13-18(21)7-10-20(17)24/h1,5-10,13,15,22,24H,11-12,14H2,2-3H3/t15-/m1/s1
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n/an/a 310n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-B using benzylamine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluo...


Bioorg Med Chem 23: 3722-9 (2015)


Article DOI: 10.1016/j.bmc.2015.04.009
BindingDB Entry DOI: 10.7270/Q2S46TQR
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50097480
PNG
(CHEMBL3585846)
Show SMILES COc1cccnc1CNc1ccc(C[C@@H](C)N(C)CC#C)cc1
Show InChI InChI=1S/C20H25N3O/c1-5-13-23(3)16(2)14-17-8-10-18(11-9-17)22-15-19-20(24-4)7-6-12-21-19/h1,6-12,16,22H,13-15H2,2-4H3/t16-/m1/s1
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n/an/a 310n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-B using benzylamine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluo...


Bioorg Med Chem 23: 3722-9 (2015)


Article DOI: 10.1016/j.bmc.2015.04.009
BindingDB Entry DOI: 10.7270/Q2S46TQR
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50097473
PNG
(CHEMBL3585853)
Show SMILES C[C@H](Cc1ccc(NCc2cc(Cl)ccc2O)cc1)N(C)CC#C
Show InChI InChI=1S/C20H23ClN2O/c1-4-11-23(3)15(2)12-16-5-8-19(9-6-16)22-14-17-13-18(21)7-10-20(17)24/h1,5-10,13,15,22,24H,11-12,14H2,2-3H3/t15-/m1/s1
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n/an/a 700n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A using p-tyramine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluor...


Bioorg Med Chem 23: 3722-9 (2015)


Article DOI: 10.1016/j.bmc.2015.04.009
BindingDB Entry DOI: 10.7270/Q2S46TQR
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50097480
PNG
(CHEMBL3585846)
Show SMILES COc1cccnc1CNc1ccc(C[C@@H](C)N(C)CC#C)cc1
Show InChI InChI=1S/C20H25N3O/c1-5-13-23(3)16(2)14-17-8-10-18(11-9-17)22-15-19-20(24-4)7-6-12-21-19/h1,6-12,16,22H,13-15H2,2-4H3/t16-/m1/s1
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n/an/a 3.41E+3n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A using p-tyramine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluor...


Bioorg Med Chem 23: 3722-9 (2015)


Article DOI: 10.1016/j.bmc.2015.04.009
BindingDB Entry DOI: 10.7270/Q2S46TQR
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50097483
PNG
(CHEMBL3585855)
Show SMILES C[C@H](Cc1ccc(NCc2cc(ccc2O)[N+]([O-])=O)cc1)N(C)CC#C
Show InChI InChI=1S/C20H23N3O3/c1-4-11-22(3)15(2)12-16-5-7-18(8-6-16)21-14-17-13-19(23(25)26)9-10-20(17)24/h1,5-10,13,15,21,24H,11-12,14H2,2-3H3/t15-/m1/s1
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n/an/a 950n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-B using benzylamine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluo...


Bioorg Med Chem 23: 3722-9 (2015)


Article DOI: 10.1016/j.bmc.2015.04.009
BindingDB Entry DOI: 10.7270/Q2S46TQR
More data for this
Ligand-Target Pair
Phosphodiesterase 4 and 5 (PDE4 and PDE5)


(Homo sapiens (Human))
BDBM50097484
PNG
(CHEMBL3585871)
Show SMILES OC(CO\N=C\c1ccc(OC(F)F)c(OC2CCCC2)c1)CN1CCC(O)CC1
Show InChI InChI=1S/C21H30F2N2O5/c22-21(23)30-19-6-5-15(11-20(19)29-18-3-1-2-4-18)12-24-28-14-17(27)13-25-9-7-16(26)8-10-25/h5-6,11-12,16-18,21,26-27H,1-4,7-10,13-14H2/b24-12+
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n/an/a 2.54E+3n/an/an/an/an/an/a



University of Genoa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate by fluorescence polarization assay


Bioorg Med Chem 23: 3426-35 (2015)


Article DOI: 10.1016/j.bmc.2015.04.027
BindingDB Entry DOI: 10.7270/Q2NC62ZZ
More data for this
Ligand-Target Pair
Phosphodiesterase 4 and 5 (PDE4 and PDE5)


(Homo sapiens (Human))
BDBM50097485
PNG
(CHEMBL3585872)
Show SMILES CC1CN(CC(C)O1)NCC(O)CO\N=C\c1ccc(OC(F)F)c(OC2CCCC2)c1
Show InChI InChI=1S/C22H33F2N3O5/c1-15-12-27(13-16(2)30-15)25-11-18(28)14-29-26-10-17-7-8-20(32-22(23)24)21(9-17)31-19-5-3-4-6-19/h7-10,15-16,18-19,22,25,28H,3-6,11-14H2,1-2H3/b26-10+
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n/an/a 190n/an/an/an/an/an/a



University of Genoa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate by fluorescence polarization assay


Bioorg Med Chem 23: 3426-35 (2015)


Article DOI: 10.1016/j.bmc.2015.04.027
BindingDB Entry DOI: 10.7270/Q2NC62ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073078
PNG
(CHEMBL3410721)
Show SMILES CCCOc1c(OC)ccc2cc(C(=O)NC3CCCCC3)c(=O)oc12
Show InChI InChI=1S/C20H25NO5/c1-3-11-25-18-16(24-2)10-9-13-12-15(20(23)26-17(13)18)19(22)21-14-7-5-4-6-8-14/h9-10,12,14H,3-8,11H2,1-2H3,(H,21,22)
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n/an/a 807n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB2 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073077
PNG
(CHEMBL3410720)
Show SMILES CCCCOc1cc(Br)cc2cc(C(=O)NC(C)C)c(=O)oc12
Show InChI InChI=1S/C17H20BrNO4/c1-4-5-6-22-14-9-12(18)7-11-8-13(16(20)19-10(2)3)17(21)23-15(11)14/h7-10H,4-6H2,1-3H3,(H,19,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB2 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073076
PNG
(CHEMBL3407533)
Show SMILES CCCCOc1cc(Br)cc2cc(C(=O)NN3CCOCC3)c(=O)oc12
Show InChI InChI=1S/C18H21BrN2O5/c1-2-3-6-25-15-11-13(19)9-12-10-14(18(23)26-16(12)15)17(22)20-21-4-7-24-8-5-21/h9-11H,2-8H2,1H3,(H,20,22)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB2 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073074
PNG
(CHEMBL3410718)
Show SMILES Brc1cc(OCC2CC2)c2oc(=O)c(cc2c1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C20H22BrNO4/c21-14-8-13-9-16(19(23)22-15-4-2-1-3-5-15)20(24)26-18(13)17(10-14)25-11-12-6-7-12/h8-10,12,15H,1-7,11H2,(H,22,23)
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n/an/a 746n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB2 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073071
PNG
(CHEMBL3410715)
Show SMILES CCCCOc1cc(Br)cc2cc(C(=O)NC3CCCCC3)c(=O)oc12
Show InChI InChI=1S/C20H24BrNO4/c1-2-3-9-25-17-12-14(21)10-13-11-16(20(24)26-18(13)17)19(23)22-15-7-5-4-6-8-15/h10-12,15H,2-9H2,1H3,(H,22,23)
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n/an/a 90n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB2 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50073070
PNG
(CHEMBL3410716)
Show SMILES CCCCCOc1cc(Br)cc2cc(C(=O)NC3CCCCC3)c(=O)oc12
Show InChI InChI=1S/C21H26BrNO4/c1-2-3-7-10-26-18-13-15(22)11-14-12-17(21(25)27-19(14)18)20(24)23-16-8-5-4-6-9-16/h11-13,16H,2-10H2,1H3,(H,23,24)
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n/an/a 2.19E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB2 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50073076
PNG
(CHEMBL3407533)
Show SMILES CCCCOc1cc(Br)cc2cc(C(=O)NN3CCOCC3)c(=O)oc12
Show InChI InChI=1S/C18H21BrN2O5/c1-2-3-6-25-15-11-13(19)9-12-10-14(18(23)26-16(12)15)17(22)20-21-4-7-24-8-5-21/h9-11H,2-8H2,1H3,(H,20,22)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity at CB1 receptor (unknown origin) expressed in CHO cells up to 10 uM incubated for 10 mins prior to CP55940 addition by calcium mo...


Eur J Med Chem 93: 16-32 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.054
BindingDB Entry DOI: 10.7270/Q28P626S
More data for this
Ligand-Target Pair