BindingDB logo
myBDB logout

4 similar compounds to monomer 31072

Compile data set for download or QSAR
Wt: 346.3
BDBM50076249
Purchase
Wt: 387.3
BDBM50076252
Purchase
Wt: 432.4
BDBM50076253
Purchase
Wt: 343.3
BDBM50076255
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50076249,50076252,50076253,50076255   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076249
PNG
(CHEMBL3416310)
Show SMILES Cc1occc1-c1nnc(SC2=CS(=O)(=O)c3ccccc23)o1
Show InChI InChI=1S/C15H10N2O4S2/c1-9-10(6-7-20-9)14-16-17-15(21-14)22-12-8-23(18,19)13-5-3-2-4-11(12)13/h2-8H,1H3
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.50E+3n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076252
PNG
(CHEMBL3416313)
Show SMILES [O-][N+](=O)c1ccccc1-c1nnc(SC2=CS(=O)(=O)c3ccccc23)o1
Show InChI InChI=1S/C16H9N3O5S2/c20-19(21)12-7-3-1-5-10(12)15-17-18-16(24-15)25-13-9-26(22,23)14-8-4-2-6-11(13)14/h1-9H
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.70E+3n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076253
PNG
(CHEMBL3416314)
Show SMILES COc1cc(cc(OC)c1OC)-c1nnc(SC2=CS(=O)(=O)c3ccccc23)o1
Show InChI InChI=1S/C19H16N2O6S2/c1-24-13-8-11(9-14(25-2)17(13)26-3)18-20-21-19(27-18)28-15-10-29(22,23)16-7-5-4-6-12(15)16/h4-10H,1-3H3
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076255
PNG
(CHEMBL3416316)
Show SMILES O=S1(=O)C=C(Sc2nnc(o2)-c2ccncc2)c2ccccc12
Show InChI InChI=1S/C15H9N3O3S2/c19-23(20)9-12(11-3-1-2-4-13(11)23)22-15-18-17-14(21-15)10-5-7-16-8-6-10/h1-9H
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.60E+3n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076249
PNG
(CHEMBL3416310)
Show SMILES Cc1occc1-c1nnc(SC2=CS(=O)(=O)c3ccccc23)o1
Show InChI InChI=1S/C15H10N2O4S2/c1-9-10(6-7-20-9)14-16-17-15(21-14)22-12-8-23(18,19)13-5-3-2-4-11(12)13/h2-8H,1H3
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076255
PNG
(CHEMBL3416316)
Show SMILES O=S1(=O)C=C(Sc2nnc(o2)-c2ccncc2)c2ccccc12
Show InChI InChI=1S/C15H9N3O3S2/c19-23(20)9-12(11-3-1-2-4-13(11)23)22-15-18-17-14(21-15)10-5-7-16-8-6-10/h1-9H
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of yeast histone acetyltransferase Gcn5-Ada2-Ada3 complex using tetramer and [3H]-acetyl-CoA assessed as acetate incorporation after 30 mi...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076253
PNG
(CHEMBL3416314)
Show SMILES COc1cc(cc(OC)c1OC)-c1nnc(SC2=CS(=O)(=O)c3ccccc23)o1
Show InChI InChI=1S/C19H16N2O6S2/c1-24-13-8-11(9-14(25-2)17(13)26-3)18-20-21-19(27-18)28-15-10-29(22,23)16-7-5-4-6-12(15)16/h4-10H,1-3H3
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.10E+3n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076255
PNG
(CHEMBL3416316)
Show SMILES O=S1(=O)C=C(Sc2nnc(o2)-c2ccncc2)c2ccccc12
Show InChI InChI=1S/C15H9N3O3S2/c19-23(20)9-12(11-3-1-2-4-13(11)23)22-15-18-17-14(21-15)10-5-7-16-8-6-10/h1-9H
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.50E+3n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076255
PNG
(CHEMBL3416316)
Show SMILES O=S1(=O)C=C(Sc2nnc(o2)-c2ccncc2)c2ccccc12
Show InChI InChI=1S/C15H9N3O3S2/c19-23(20)9-12(11-3-1-2-4-13(11)23)22-15-18-17-14(21-15)10-5-7-16-8-6-10/h1-9H
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using [3H]-acetyl-CoA assessed as acetate incorp...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase p300


(Homo sapiens (Human))
BDBM50076255
PNG
(CHEMBL3416316)
Show SMILES O=S1(=O)C=C(Sc2nnc(o2)-c2ccncc2)c2ccccc12
Show InChI InChI=1S/C15H9N3O3S2/c19-23(20)9-12(11-3-1-2-4-13(11)23)22-15-18-17-14(21-15)10-5-7-16-8-6-10/h1-9H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.20E+3n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant histone acetyltransferase p300 (unknown origin) using dH3-H4 tetramer and [3H]-acetyl-CoA assessed as acetate incorporation...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair
Histone acetyltransferase GCN5


(Saccharomyces cerevisiae S288c)
BDBM50076252
PNG
(CHEMBL3416313)
Show SMILES [O-][N+](=O)c1ccccc1-c1nnc(SC2=CS(=O)(=O)c3ccccc23)o1
Show InChI InChI=1S/C16H9N3O5S2/c20-19(21)12-7-3-1-5-10(12)15-17-18-16(24-15)25-13-9-26(22,23)14-8-4-2-6-11(13)14/h1-9H
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



Mayo Clinic College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...


J Med Chem 58: 2091-113 (2015)


Article DOI: 10.1021/jm5019093
BindingDB Entry DOI: 10.7270/Q26M38J9
More data for this
Ligand-Target Pair