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2 similar compounds to monomer 50087856

Compile data set for download or QSAR
Wt: 507.6
BDBM50087858
Wt: 477.5
BDBM50087863

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087858,50087863   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear proteasome inhibitor UBLCP1


(Homo sapiens (Human))
BDBM50087863
PNG
(CHEMBL3426910)
Show SMILES CCCCC(Oc1cc(O)c(cc1C#Cc1ccccc1)C(O)=O)C(=O)NC1CCCCCCC1
Show InChI InChI=1S/C29H35NO5/c1-2-3-16-26(28(32)30-23-14-10-5-4-6-11-15-23)35-27-20-25(31)24(29(33)34)19-22(27)18-17-21-12-8-7-9-13-21/h7-9,12-13,19-20,23,26,31H,2-6,10-11,14-16H2,1H3,(H,30,32)(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.30E+3n/an/an/an/a6.0n/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of His6-tagged UBLCP1 (unknown origin) expressed in Escherichia coli BL21 cells using pNPP as substrate at pH 6 at 25 degC by spectrophoto...


Bioorg Med Chem 23: 2798-809 (2015)


Article DOI: 10.1016/j.bmc.2015.03.066
BindingDB Entry DOI: 10.7270/Q2VD7168
More data for this
Ligand-Target Pair
Nuclear proteasome inhibitor UBLCP1


(Homo sapiens (Human))
BDBM50087858
PNG
(CHEMBL3425525)
Show SMILES CCCCC(Oc1cc(O)c(cc1C#Cc1ccccc1OC)C(O)=O)C(=O)NC1CCCCCCC1
Show InChI InChI=1S/C30H37NO6/c1-3-4-15-27(29(33)31-23-13-8-6-5-7-9-14-23)37-28-20-25(32)24(30(34)35)19-22(28)18-17-21-12-10-11-16-26(21)36-2/h10-12,16,19-20,23,27,32H,3-9,13-15H2,1-2H3,(H,31,33)(H,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+3n/an/an/an/a6.0n/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of His6-tagged UBLCP1 (unknown origin) expressed in Escherichia coli BL21 cells using pNPP as substrate at pH 6 at 25 degC by spectrophoto...


Bioorg Med Chem 23: 2798-809 (2015)


Article DOI: 10.1016/j.bmc.2015.03.066
BindingDB Entry DOI: 10.7270/Q2VD7168
More data for this
Ligand-Target Pair