BindingDB logo
myBDB logout

1 similar compounds to monomer 50125044

Wt: 175.2
BDBM50094968

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50094968   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Rattus norvegicus (Rat))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.80n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Affinity at alpha4-beta2 nACh receptors in rat brain (minus cerebellum) homogenates.


Bioorg Med Chem Lett 13: 733-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01031-4
BindingDB Entry DOI: 10.7270/Q2FT8NKF
More data for this
Ligand-Target Pair
Alpha-2B adrenergic receptor


(Homo sapiens (Human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards the Alpha-2B adrenergic receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 3A


(Homo sapiens (Human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards 5-hydroxytryptamine 3 receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards 5-hydroxytryptamine 5A receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards 5-hydroxytryptamine 7 receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards the 5-hydroxytryptamine 1D receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Adrenergic alpha1B


(Homo sapiens (Human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards the Alpha-1B adrenergic receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards the Alpha-1A adrenergic receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards 5-hydroxytryptamine 6 receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards 5-hydroxytryptamine 2C receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards Alpha-2A adrenergic receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards the receptor rat 5-hydroxytryptamine 1B receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Alpha-2C adrenergic receptor


(Homo sapiens (Human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards the Alpha-2C adrenergic receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards 5-hydroxytryptamine 2A receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M4


(HUMAN M3)
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards muscarinic receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards the Beta-1 adrenergic receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5HT1A)


(Mus musculus (Mouse))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards 5-hydroxytryptamine 1A receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50094968
PNG
(3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-py...)
Show SMILES CN1CCN=C1Cc1cccnc1
Show InChI InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita di Camerino

Curated by ChEMBL


Assay Description
The binding affinity towards the Beta-2 adrenergic receptor; No affinity


J Med Chem 45: 4724-31 (2002)


Article DOI: 10.1021/jm020188s
BindingDB Entry DOI: 10.7270/Q2ZW1K88
More data for this
Ligand-Target Pair