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1 similar compounds to monomer 51317

Wt: 198.1
BDBM50099711

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099711   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50099711
PNG
(CHEMBL38066 | Naphtho[1,2-b]furan-4,5-dione)
Show SMILES O=C1c2ccoc2-c2ccccc2C1=O
Show InChI InChI=1S/C12H6O3/c13-10-7-3-1-2-4-8(7)12-9(11(10)14)5-6-15-12/h1-6H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrate


J Med Chem 44: 1777-93 (2001)

More data for this
Ligand-Target Pair
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50099711
PNG
(CHEMBL38066 | Naphtho[1,2-b]furan-4,5-dione)
Show SMILES O=C1c2ccoc2-c2ccccc2C1=O
Show InChI InChI=1S/C12H6O3/c13-10-7-3-1-2-4-8(7)12-9(11(10)14)5-6-15-12/h1-6H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrate


J Med Chem 44: 1777-93 (2001)

More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (human))
BDBM50099711
PNG
(CHEMBL38066 | Naphtho[1,2-b]furan-4,5-dione)
Show SMILES O=C1c2ccoc2-c2ccccc2C1=O
Show InChI InChI=1S/C12H6O3/c13-10-7-3-1-2-4-8(7)12-9(11(10)14)5-6-15-12/h1-6H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration against PTP1B using lck as substrate


J Med Chem 44: 1777-93 (2001)

More data for this
Ligand-Target Pair