BindingDB logo
myBDB logout

1 similar compounds to monomer 50118456

Compile data set for download or QSAR
Wt: 285.2
BDBM50118440

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50118440   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melatonin receptor


(Homo sapiens (Human))
BDBM50118440
PNG
(2,2,2-Trifluoro-N-[2-(6-methoxy-3H-inden-1-yl)-eth...)
Show SMILES COc1ccc2CC=C(CCNC(=O)C(F)(F)F)c2c1
Show InChI InChI=1S/C14H14F3NO2/c1-20-11-5-4-9-2-3-10(12(9)8-11)6-7-18-13(19)14(15,16)17/h3-5,8H,2,6-7H2,1H3,(H,18,19)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.0408n/an/an/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Ability to inhibit 2-[125I]iodomelatonin specific binding to human melatonin receptor type 1A (MT1) expressed in CHO cells.


J Med Chem 45: 4212-21 (2002)


Article DOI: 10.1021/jm020114g
BindingDB Entry DOI: 10.7270/Q2J102HG
More data for this
Ligand-Target Pair
Ribosyldihydronicotinamide dehydrogenase [quinone]


(Homo sapiens (Human))
BDBM50118440
PNG
(2,2,2-Trifluoro-N-[2-(6-methoxy-3H-inden-1-yl)-eth...)
Show SMILES COc1ccc2CC=C(CCNC(=O)C(F)(F)F)c2c1
Show InChI InChI=1S/C14H14F3NO2/c1-20-11-5-4-9-2-3-10(12(9)8-11)6-7-18-13(19)14(15,16)17/h3-5,8H,2,6-7H2,1H3,(H,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
9.10n/an/an/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Ability to inhibit 2-[125I]iodomelatonin specific binding to melatonin receptor 3 (MT3) of Syrian hamster brain.


J Med Chem 45: 4212-21 (2002)


Article DOI: 10.1021/jm020114g
BindingDB Entry DOI: 10.7270/Q2J102HG
More data for this
Ligand-Target Pair