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16 similar compounds to monomer 50124990

Wt: 571.6
BDBM50124972
Wt: 556.0
BDBM50124976
Wt: 546.6
BDBM50124978
Wt: 606.1
BDBM50124979
Wt: 572.6
BDBM50124982
Wt: 536.6
BDBM50124986
Wt: 599.7
BDBM50124988
Wt: 539.6
BDBM50124989
Wt: 606.1
BDBM50124993
Wt: 600.5
BDBM50124994
Wt: 556.0
BDBM50124995
Wt: 552.6
BDBM50124997
Wt: 571.6
BDBM50124999
Wt: 521.6
BDBM50125001
Wt: 590.5
BDBM50125004
Displayed 1 to 15 (of 16 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 47 hits for monomerid = 50124972,50124976,50124978,50124979,50124982,50124986,50124988,50124989,50124993,50124994,50124995,50124997,50124999,50125001,50125004   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124979
PNG
(2-[4-(5-Chloro-naphthalene-2-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2c(Cl)cccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-19-4-1-3-16-13-17(6-7-18(16)19)40(37,38)33-11-10-32(22(35)15-33)14-21(34)31-20(5-2-8-30-25(27)28)23(36)24-29-9-12-39-24/h1,3-4,6-7,9,12-13,20H,2,5,8,10-11,14-15H2,(H,31,34)(H4,27,28,30)
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1.30n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124995
PNG
(2-[4-(4-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)/t16-/m1/s1
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2.30n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124972
PNG
(CHEMBL163174 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2ccccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-9-3-6-20(23(35)24-28-10-13-38-24)30-21(33)15-31-11-12-32(16-22(31)34)39(36,37)19-8-7-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-8,10,13-14,20H,3,6,9,11-12,15-16H2,(H,30,33)(H4,26,27,29)
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2.70n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124995
PNG
(2-[4-(4-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)/t16-/m1/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50125001
PNG
(2-(4-Benzenesulfonyl-2-oxo-piperazin-1-yl)-N-[(R)-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccccc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H27N7O5S2/c22-21(23)25-8-4-7-16(19(31)20-24-9-12-34-20)26-17(29)13-27-10-11-28(14-18(27)30)35(32,33)15-5-2-1-3-6-15/h1-3,5-6,9,12,16H,4,7-8,10-11,13-14H2,(H,26,29)(H4,22,23,25)/t16-/m1/s1
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n/an/a 417n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124986
PNG
(2-[4-(4-Amino-benzenesulfonyl)-2-oxo-piperazin-1-y...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(N)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H28N8O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13,22H2,(H,27,30)(H4,23,24,26)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50125004
PNG
(2-[4-(3,4-Dichloro-benzenesulfonyl)-2-oxo-piperazi...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)c(Cl)c1)C(=O)c1nccs1
Show InChI InChI=1S/C21H25Cl2N7O5S2/c22-14-4-3-13(10-15(14)23)37(34,35)30-8-7-29(18(32)12-30)11-17(31)28-16(2-1-5-27-21(24)25)19(33)20-26-6-9-36-20/h3-4,6,9-10,16H,1-2,5,7-8,11-12H2,(H,28,31)(H4,24,25,27)
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n/an/a 1n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (human))
BDBM50124972
PNG
(CHEMBL163174 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2ccccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-9-3-6-20(23(35)24-28-10-13-38-24)30-21(33)15-31-11-12-32(16-22(31)34)39(36,37)19-8-7-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-8,10,13-14,20H,3,6,9,11-12,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/a 1.85E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against tissue plasminogen activator (tissue plasminogen activator)


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124994
PNG
(2-[4-(4-Bromo-benzenesulfonyl)-2-oxo-piperazin-1-y...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Br)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26BrN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)
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n/an/a 809n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124997
PNG
(CHEMBL349629 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(NO)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H28N8O6S2/c22-21(23)25-7-1-2-16(19(32)20-24-8-11-36-20)26-17(30)12-28-9-10-29(13-18(28)31)37(34,35)15-5-3-14(27-33)4-6-15/h3-6,8,11,16,27,33H,1-2,7,9-10,12-13H2,(H,26,30)(H4,22,23,25)
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n/an/a 10n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124993
PNG
(2-[4-(5-Chloro-naphthalene-1-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cccc2c(Cl)cccc12)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-18-6-1-5-17-16(18)4-2-8-20(17)40(37,38)33-12-11-32(22(35)15-33)14-21(34)31-19(7-3-9-30-25(27)28)23(36)24-29-10-13-39-24/h1-2,4-6,8,10,13,19H,3,7,9,11-12,14-15H2,(H,31,34)(H4,27,28,30)
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n/an/a 0.620n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124994
PNG
(2-[4-(4-Bromo-benzenesulfonyl)-2-oxo-piperazin-1-y...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Br)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26BrN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)
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n/an/a 0.700n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124989
PNG
(2-[4-(4-Fluoro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(F)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26FN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)
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n/an/a 2n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124976
PNG
(2-[4-(3-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cccc(Cl)c1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-1-4-15(11-14)36(33,34)29-9-8-28(18(31)13-29)12-17(30)27-16(5-2-6-26-21(23)24)19(32)20-25-7-10-35-20/h1,3-4,7,10-11,16H,2,5-6,8-9,12-13H2,(H,27,30)(H4,23,24,26)
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n/an/a 5n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124982
PNG
(CHEMBL163213 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cccc2cnccc12)C(=O)c1nccs1
Show InChI InChI=1S/C24H28N8O5S2/c25-24(26)29-7-2-4-18(22(35)23-28-9-12-38-23)30-20(33)14-31-10-11-32(15-21(31)34)39(36,37)19-5-1-3-16-13-27-8-6-17(16)19/h1,3,5-6,8-9,12-13,18H,2,4,7,10-11,14-15H2,(H,30,33)(H4,25,26,29)
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n/an/a 1n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Vitamin K-dependent protein C


(Homo sapiens (human))
BDBM50124972
PNG
(CHEMBL163174 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2ccccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-9-3-6-20(23(35)24-28-10-13-38-24)30-21(33)15-31-11-12-32(16-22(31)34)39(36,37)19-8-7-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-8,10,13-14,20H,3,6,9,11-12,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/a>1.80E+5n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against activated protein C (aPC)


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124978
PNG
(2-[4-(4-Cyano-benzenesulfonyl)-2-oxo-piperazin-1-y...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(cc1)C#N)C(=O)c1nccs1
Show InChI InChI=1S/C22H26N8O5S2/c23-12-15-3-5-16(6-4-15)37(34,35)30-10-9-29(19(32)14-30)13-18(31)28-17(2-1-7-27-22(24)25)20(33)21-26-8-11-36-21/h3-6,8,11,17H,1-2,7,9-10,13-14H2,(H,28,31)(H4,24,25,27)
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n/an/a 32n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124988
PNG
(CHEMBL159716 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES CS(=O)(=O)c1ccc(cc1)S(=O)(=O)N1CCN(CC(=O)NC(CCCNC(N)=N)C(=O)c2nccs2)C(=O)C1
Show InChI InChI=1S/C22H29N7O7S3/c1-38(33,34)15-4-6-16(7-5-15)39(35,36)29-11-10-28(19(31)14-29)13-18(30)27-17(3-2-8-26-22(23)24)20(32)21-25-9-12-37-21/h4-7,9,12,17H,2-3,8,10-11,13-14H2,1H3,(H,27,30)(H4,23,24,26)
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n/an/a 85n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124972
PNG
(CHEMBL163174 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2ccccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-9-3-6-20(23(35)24-28-10-13-38-24)30-21(33)15-31-11-12-32(16-22(31)34)39(36,37)19-8-7-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-8,10,13-14,20H,3,6,9,11-12,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Vitamin K-dependent protein C


(Homo sapiens (human))
BDBM50124995
PNG
(2-[4-(4-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)/t16-/m1/s1
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n/an/a>1.80E+5n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against activated protein C (aPC)


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124999
PNG
(CHEMBL163799 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cccc2ccccc12)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-10-4-8-19(23(35)24-28-11-14-38-24)30-21(33)15-31-12-13-32(16-22(31)34)39(36,37)20-9-3-6-17-5-1-2-7-18(17)20/h1-3,5-7,9,11,14,19H,4,8,10,12-13,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/a 2n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50125001
PNG
(2-(4-Benzenesulfonyl-2-oxo-piperazin-1-yl)-N-[(R)-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccccc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H27N7O5S2/c22-21(23)25-8-4-7-16(19(31)20-24-9-12-34-20)26-17(29)13-27-10-11-28(14-18(27)30)35(32,33)15-5-2-1-3-6-15/h1-3,5-6,9,12,16H,4,7-8,10-11,13-14H2,(H,26,29)(H4,22,23,25)/t16-/m1/s1
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n/an/a 8n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM50124979
PNG
(2-[4-(5-Chloro-naphthalene-2-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2c(Cl)cccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-19-4-1-3-16-13-17(6-7-18(16)19)40(37,38)33-11-10-32(22(35)15-33)14-21(34)31-20(5-2-8-30-25(27)28)23(36)24-29-9-12-39-24/h1,3-4,6-7,9,12-13,20H,2,5,8,10-11,14-15H2,(H,31,34)(H4,27,28,30)
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n/an/a 20.5n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Trypsin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124999
PNG
(CHEMBL163799 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cccc2ccccc12)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-10-4-8-19(23(35)24-28-11-14-38-24)30-21(33)15-31-12-13-32(16-22(31)34)39(36,37)20-9-3-6-17-5-1-2-7-18(17)20/h1-3,5-7,9,11,14,19H,4,8,10,12-13,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/a 118n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124989
PNG
(2-[4-(4-Fluoro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(F)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26FN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)
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n/an/a 751n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50125004
PNG
(2-[4-(3,4-Dichloro-benzenesulfonyl)-2-oxo-piperazi...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)c(Cl)c1)C(=O)c1nccs1
Show InChI InChI=1S/C21H25Cl2N7O5S2/c22-14-4-3-13(10-15(14)23)37(34,35)30-8-7-29(18(32)12-30)11-17(31)28-16(2-1-5-27-21(24)25)19(33)20-26-6-9-36-20/h3-4,6,9-10,16H,1-2,5,7-8,11-12H2,(H,28,31)(H4,24,25,27)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (human))
BDBM50124995
PNG
(2-[4-(4-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)/t16-/m1/s1
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n/an/a 1.07E+4n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Plasmin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124997
PNG
(CHEMBL349629 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(NO)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H28N8O6S2/c22-21(23)25-7-1-2-16(19(32)20-24-8-11-36-20)26-17(30)12-28-9-10-29(13-18(28)31)37(34,35)15-5-3-14(27-33)4-6-15/h3-6,8,11,16,27,33H,1-2,7,9-10,12-13H2,(H,26,30)(H4,22,23,25)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124993
PNG
(2-[4-(5-Chloro-naphthalene-1-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cccc2c(Cl)cccc12)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-18-6-1-5-17-16(18)4-2-8-20(17)40(37,38)33-12-11-32(22(35)15-33)14-21(34)31-19(7-3-9-30-25(27)28)23(36)24-29-10-13-39-24/h1-2,4-6,8,10,13,19H,3,7,9,11-12,14-15H2,(H,31,34)(H4,27,28,30)
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n/an/a 185n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124979
PNG
(2-[4-(5-Chloro-naphthalene-2-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2c(Cl)cccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-19-4-1-3-16-13-17(6-7-18(16)19)40(37,38)33-11-10-32(22(35)15-33)14-21(34)31-20(5-2-8-30-25(27)28)23(36)24-29-9-12-39-24/h1,3-4,6-7,9,12-13,20H,2,5,8,10-11,14-15H2,(H,31,34)(H4,27,28,30)
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n/an/a 2.00E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM50124972
PNG
(CHEMBL163174 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2ccccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-9-3-6-20(23(35)24-28-10-13-38-24)30-21(33)15-31-11-12-32(16-22(31)34)39(36,37)19-8-7-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-8,10,13-14,20H,3,6,9,11-12,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/a 39.1n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Trypsin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM50124995
PNG
(2-[4-(4-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)/t16-/m1/s1
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n/an/a 10.8n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Trypsin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124988
PNG
(CHEMBL159716 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES CS(=O)(=O)c1ccc(cc1)S(=O)(=O)N1CCN(CC(=O)NC(CCCNC(N)=N)C(=O)c2nccs2)C(=O)C1
Show InChI InChI=1S/C22H29N7O7S3/c1-38(33,34)15-4-6-16(7-5-15)39(35,36)29-11-10-28(19(31)14-29)13-18(30)27-17(3-2-8-26-22(23)24)20(32)21-25-9-12-37-21/h4-7,9,12,17H,2-3,8,10-11,13-14H2,1H3,(H,27,30)(H4,23,24,26)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (human))
BDBM50124979
PNG
(2-[4-(5-Chloro-naphthalene-2-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2c(Cl)cccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-19-4-1-3-16-13-17(6-7-18(16)19)40(37,38)33-11-10-32(22(35)15-33)14-21(34)31-20(5-2-8-30-25(27)28)23(36)24-29-9-12-39-24/h1,3-4,6-7,9,12-13,20H,2,5,8,10-11,14-15H2,(H,31,34)(H4,27,28,30)
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n/an/a 1.88E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Plasmin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124976
PNG
(2-[4-(3-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cccc(Cl)c1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-1-4-15(11-14)36(33,34)29-9-8-28(18(31)13-29)12-17(30)27-16(5-2-6-26-21(23)24)19(32)20-25-7-10-35-20/h1,3-4,7,10-11,16H,2,5-6,8-9,12-13H2,(H,27,30)(H4,23,24,26)
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n/an/a 134n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (human))
BDBM50124979
PNG
(2-[4-(5-Chloro-naphthalene-2-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2c(Cl)cccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-19-4-1-3-16-13-17(6-7-18(16)19)40(37,38)33-11-10-32(22(35)15-33)14-21(34)31-20(5-2-8-30-25(27)28)23(36)24-29-9-12-39-24/h1,3-4,6-7,9,12-13,20H,2,5,8,10-11,14-15H2,(H,31,34)(H4,27,28,30)
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PubMed
n/an/a 740n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against tissue plasminogen activator (tissue plasminogen activator)


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124978
PNG
(2-[4-(4-Cyano-benzenesulfonyl)-2-oxo-piperazin-1-y...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(cc1)C#N)C(=O)c1nccs1
Show InChI InChI=1S/C22H26N8O5S2/c23-12-15-3-5-16(6-4-15)37(34,35)30-10-9-29(19(32)14-30)13-18(31)28-17(2-1-7-27-22(24)25)20(33)21-26-8-11-36-21/h3-6,8,11,17H,1-2,7,9-10,13-14H2,(H,28,31)(H4,24,25,27)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (human))
BDBM50124982
PNG
(CHEMBL163213 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cccc2cnccc12)C(=O)c1nccs1
Show InChI InChI=1S/C24H28N8O5S2/c25-24(26)29-7-2-4-18(22(35)23-28-9-12-38-23)30-20(33)14-31-10-11-32(15-21(31)34)39(36,37)19-5-1-3-16-13-27-8-6-17(16)19/h1,3,5-6,8-9,12-13,18H,2,4,7,10-11,14-15H2,(H,30,33)(H4,25,26,29)
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n/an/a 267n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against serine protease thrombin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124986
PNG
(2-[4-(4-Amino-benzenesulfonyl)-2-oxo-piperazin-1-y...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(N)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H28N8O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13,22H2,(H,27,30)(H4,23,24,26)
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n/an/a 6n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124972
PNG
(CHEMBL163174 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2ccccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-9-3-6-20(23(35)24-28-10-13-38-24)30-21(33)15-31-11-12-32(16-22(31)34)39(36,37)19-8-7-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-8,10,13-14,20H,3,6,9,11-12,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/an/an/an/a 0.132 6.30E+6n/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124995
PNG
(2-[4-(4-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)/t16-/m1/s1
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n/an/a 2n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124995
PNG
(2-[4-(4-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)/t16-/m1/s1
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PubMed
n/an/an/an/an/a 0.190 3.40E+6n/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124979
PNG
(2-[4-(5-Chloro-naphthalene-2-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2c(Cl)cccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-19-4-1-3-16-13-17(6-7-18(16)19)40(37,38)33-11-10-32(22(35)15-33)14-21(34)31-20(5-2-8-30-25(27)28)23(36)24-29-9-12-39-24/h1,3-4,6-7,9,12-13,20H,2,5,8,10-11,14-15H2,(H,31,34)(H4,27,28,30)
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PubMed
n/an/a 0.790n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Vitamin K-dependent protein C


(Homo sapiens (human))
BDBM50124979
PNG
(2-[4-(5-Chloro-naphthalene-2-sulfonyl)-2-oxo-piper...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2c(Cl)cccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H28ClN7O5S2/c26-19-4-1-3-16-13-17(6-7-18(16)19)40(37,38)33-11-10-32(22(35)15-33)14-21(34)31-20(5-2-8-30-25(27)28)23(36)24-29-9-12-39-24/h1,3-4,6-7,9,12-13,20H,2,5,8,10-11,14-15H2,(H,31,34)(H4,27,28,30)
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PubMed
n/an/a 1.70E+5n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against activated protein C (aPC)


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50124972
PNG
(CHEMBL163174 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2ccccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-9-3-6-20(23(35)24-28-10-13-38-24)30-21(33)15-31-11-12-32(16-22(31)34)39(36,37)19-8-7-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-8,10,13-14,20H,3,6,9,11-12,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/a 8n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against factor Xa


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (human))
BDBM50124972
PNG
(CHEMBL163174 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Show SMILES NC(=N)NCCCC(NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc2ccccc2c1)C(=O)c1nccs1
Show InChI InChI=1S/C25H29N7O5S2/c26-25(27)29-9-3-6-20(23(35)24-28-10-13-38-24)30-21(33)15-31-11-12-32(16-22(31)34)39(36,37)19-8-7-17-4-1-2-5-18(17)14-19/h1-2,4-5,7-8,10,13-14,20H,3,6,9,11-12,15-16H2,(H,30,33)(H4,26,27,29)
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n/an/a 6.96E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Plasmin


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (human))
BDBM50124995
PNG
(2-[4-(4-Chloro-benzenesulfonyl)-2-oxo-piperazin-1-...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)CN1CCN(CC1=O)S(=O)(=O)c1ccc(Cl)cc1)C(=O)c1nccs1
Show InChI InChI=1S/C21H26ClN7O5S2/c22-14-3-5-15(6-4-14)36(33,34)29-10-9-28(18(31)13-29)12-17(30)27-16(2-1-7-26-21(23)24)19(32)20-25-8-11-35-20/h3-6,8,11,16H,1-2,7,9-10,12-13H2,(H,27,30)(H4,23,24,26)/t16-/m1/s1
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PubMed
n/an/a 1.88E+3n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against tissue plasminogen activator (tissue plasminogen activator)


Bioorg Med Chem Lett 13: 723-8 (2003)

More data for this
Ligand-Target Pair