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1 similar compounds to monomer 50128338

Compile data set for download or QSAR
Wt: 310.3
BDBM50128330

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128330   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 12


(Homo sapiens (Human))
BDBM50128330
PNG
(CHEMBL3629010)
Show SMILES CC(C)n1nc(Nc2cc(ccn2)C#N)cc1C1CCNCC1
Show InChI InChI=1S/C17H22N6/c1-12(2)23-15(14-4-6-19-7-5-14)10-17(22-23)21-16-9-13(11-18)3-8-20-16/h3,8-10,12,14,19H,4-7H2,1-2H3,(H,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
160n/an/an/an/an/an/an/an/a



WuXi AppTec Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of N-terminally GST- tagged human DLK catalytic domain (1 to 520 amino acids) using N-terminally HIS-tagged MKK4 K131M as substrate incuba...


J Med Chem 58: 8182-99 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01072
BindingDB Entry DOI: 10.7270/Q27D2WZ0
More data for this
Ligand-Target Pair