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1 similar compounds to monomer 50131665

Wt: 217.2
BDBM50131670

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131670   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50131670
PNG
(C-(6-Methoxy-4,5-dihydro-3H-naphtho[1,8-bc]furan-5...)
Show SMILES COc1ccc2occ3CC[C@@H](CN)c1c23
Show InChI InChI=1S/C13H15NO2/c1-15-10-4-5-11-13-9(7-16-11)3-2-8(6-14)12(10)13/h4-5,7-8H,2-3,6,14H2,1H3/t8-/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
11n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI


Citation and Details
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))
BDBM50131670
PNG
(C-(6-Methoxy-4,5-dihydro-3H-naphtho[1,8-bc]furan-5...)
Show SMILES COc1ccc2occ3CC[C@@H](CN)c1c23
Show InChI InChI=1S/C13H15NO2/c1-15-10-4-5-11-13-9(7-16-11)3-2-8(6-14)12(10)13/h4-5,7-8H,2-3,6,14H2,1H3/t8-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
200n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI


Citation and Details
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (human))
BDBM50131670
PNG
(C-(6-Methoxy-4,5-dihydro-3H-naphtho[1,8-bc]furan-5...)
Show SMILES COc1ccc2occ3CC[C@@H](CN)c1c23
Show InChI InChI=1S/C13H15NO2/c1-15-10-4-5-11-13-9(7-16-11)3-2-8(6-14)12(10)13/h4-5,7-8H,2-3,6,14H2,1H3/t8-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
860n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Tested in vitro for its ability to bind to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


Citation and Details
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))
BDBM50131670
PNG
(C-(6-Methoxy-4,5-dihydro-3H-naphtho[1,8-bc]furan-5...)
Show SMILES COc1ccc2occ3CC[C@@H](CN)c1c23
Show InChI InChI=1S/C13H15NO2/c1-15-10-4-5-11-13-9(7-16-11)3-2-8(6-14)12(10)13/h4-5,7-8H,2-3,6,14H2,1H3/t8-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Tested for its ability to activate phospholipase C by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptor


Citation and Details
More data for this
Ligand-Target Pair