Compounds in cluster

57 similar compounds to monomer 50146602

Wt: 372.4 BDBM50150473	Wt: 631.8 BDBM50150463	Wt: 692.7 BDBM50150467	Wt: 191.2 BDBM50150471	Wt: 218.2 BDBM50150472
Wt: 213.7 BDBM50146582	Wt: 151.2 BDBM50146583	Wt: 569.7 BDBM50146585	Wt: 642.8 BDBM50146586	Wt: 604.7 BDBM50146587
Wt: 553.3 BDBM50146588	Wt: 686.9 BDBM50146590	Wt: 636.9 BDBM50146591	Wt: 275.3 BDBM50146599	Wt: 283.3 BDBM50146600

Displayed 1 to 15 (of 57 total ) | Next | Last >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 50150473,50150463,50150467,50150471,50150472,50146582,50146583,50146585,50146586,50146587,50146588,50146590,50146591,50146599,50146600
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50146600 (CHEMBL3763914) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assay				J Med Chem 59: 721-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01771 BindingDB Entry DOI: 10.7270/Q2K0764T
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50146599 (CHEMBL3763192) Show SMILES CC(C)c1ccccc1-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assay				J Med Chem 59: 721-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01771 BindingDB Entry DOI: 10.7270/Q2K0764T
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50146600 (CHEMBL3763914) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assay				J Med Chem 59: 721-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01771 BindingDB Entry DOI: 10.7270/Q2K0764T
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50146599 (CHEMBL3763192) Show SMILES CC(C)c1ccccc1-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assay				J Med Chem 59: 721-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01771 BindingDB Entry DOI: 10.7270/Q2K0764T
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50146585 (CHEMBL3763396) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 mins				Eur J Med Chem 108: 577-85 (2016) Article DOI: 10.1016/j.ejmech.2015.12.014 BindingDB Entry DOI: 10.7270/Q22Z17C3
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50146586 (CHEMBL3763740) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 mins				Eur J Med Chem 108: 577-85 (2016) Article DOI: 10.1016/j.ejmech.2015.12.014 BindingDB Entry DOI: 10.7270/Q22Z17C3
Universit£ degli Studi di Bari Aldo Moro Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-galactosidase (Escherichia coli)	BDBM50150471 (CHEMBL3770764) Show SMILES OCC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1CO Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graz University of Technology Curated by ChEMBL					Assay Description Inhibition of Escherichia coli lacZ beta-galactosidase using 4-nitrophenyl-beta-D-galactopyranoside as substrate preincubated up to 5 mins followed b...				Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR
Graz University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50146599 (CHEMBL3763192) Show SMILES CC(C)c1ccccc1-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assay				J Med Chem 59: 721-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01771 BindingDB Entry DOI: 10.7270/Q2K0764T
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50146599 (CHEMBL3763192) Show SMILES CC(C)c1ccccc1-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	208	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assay				J Med Chem 59: 721-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01771 BindingDB Entry DOI: 10.7270/Q2K0764T
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-galactosidase (Escherichia coli)	BDBM50150472 (CHEMBL3770736) Show SMILES NCCCC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1CO Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graz University of Technology Curated by ChEMBL					Assay Description Inhibition of Escherichia coli lacZ beta-galactosidase using 4-nitrophenyl-beta-D-galactopyranoside as substrate preincubated up to 5 mins followed b...				Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR
Graz University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50146600 (CHEMBL3763914) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assay				J Med Chem 59: 721-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01771 BindingDB Entry DOI: 10.7270/Q2K0764T
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-galactosidase (Bos taurus (Bovine))	BDBM50150471 (CHEMBL3770764) Show SMILES OCC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1CO Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graz University of Technology Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-galactosidase using 4-nitrophenyl-beta-D-galactopyranoside as substrate preincubated up to 5 mins followed by substra...				Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR
Graz University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-galactosidase (Bos taurus (Bovine))	BDBM50150472 (CHEMBL3770736) Show SMILES NCCCC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1CO Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graz University of Technology Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-galactosidase using 4-nitrophenyl-beta-D-galactopyranoside as substrate preincubated up to 5 mins followed by substra...				Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR
Graz University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50146600 (CHEMBL3763914) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assay				J Med Chem 59: 721-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01771 BindingDB Entry DOI: 10.7270/Q2K0764T
Universit£ de Reims Champagne-Ardenne Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50150471 (CHEMBL3770764) Show SMILES OCC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1CO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graz University of Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min...				Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR
Graz University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50150472 (CHEMBL3770736) Show SMILES NCCCC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1CO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Graz University of Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min...				Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR
Graz University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-Secretase Subunit APH-1A/Gamma-Secretase Subunit PEN-2/Gamma-Secretase Subunit Presenilin-1/Gamma-secretase subunit APH-1B/Nicastrin /Presenilin 2 (Homo sapiens (Human))	BDBM50150473 (CHEMBL3769671) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) production				Bioorg Med Chem Lett 26: 1498-502 (2016) Article DOI: 10.1016/j.bmcl.2015.06.020 BindingDB Entry DOI: 10.7270/Q2CZ3910
					More data for this Ligand-Target Pair
Beta-galactosidase (Homo sapiens (Human))	BDBM50150471 (CHEMBL3770764) Show SMILES OCC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1CO Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graz University of Technology Curated by ChEMBL					Assay Description Inhibition of human lysosomal beta-galactosidase using 4-MU beta-gal as substrate incubated for 96 hrs by fluorescence assay				Bioorg Med Chem Lett 26: 1438-42 (2016) Article DOI: 10.1016/j.bmcl.2016.01.059 BindingDB Entry DOI: 10.7270/Q2HQ41SR
Graz University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Calcitonin gene-related peptide (CGRP alpha) (Homo sapiens (Human))	BDBM50150467 (CHEMBL3769892) Show SMILES Show InChI	Reactome pathway GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Discovery Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from alpha CGRP in human SK-N-MC cells after 2 hrs by scintillation counter				Bioorg Med Chem Lett 26: 1229-32 (2016) Article DOI: 10.1016/j.bmcl.2016.01.026 BindingDB Entry DOI: 10.7270/Q2NG4SH3
Bristol-Myers Squibb Discovery Curated by ChEMBL					More data for this Ligand-Target Pair
Calcitonin gene-related peptide (CGRP alpha) (Homo sapiens (Human))	BDBM50150463 (CHEMBL3771371) Show SMILES Show InChI	Reactome pathway GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Discovery Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from alpha CGRP in human SK-N-MC cells after 2 hrs by scintillation counter				Bioorg Med Chem Lett 26: 1229-32 (2016) Article DOI: 10.1016/j.bmcl.2016.01.026 BindingDB Entry DOI: 10.7270/Q2NG4SH3
Bristol-Myers Squibb Discovery Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50146591 (CHEMBL3763692) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...				Eur J Med Chem 108: 623-43 (2016) Article DOI: 10.1016/j.ejmech.2015.12.001 BindingDB Entry DOI: 10.7270/Q2Z60QX5
Semmelweis University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50146590 (CHEMBL3765068) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...				Eur J Med Chem 108: 623-43 (2016) Article DOI: 10.1016/j.ejmech.2015.12.001 BindingDB Entry DOI: 10.7270/Q2Z60QX5
Semmelweis University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50146588 (CHEMBL3764145) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...				Eur J Med Chem 108: 623-43 (2016) Article DOI: 10.1016/j.ejmech.2015.12.001 BindingDB Entry DOI: 10.7270/Q2Z60QX5
Semmelweis University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50146587 (CHEMBL3764571) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...				Eur J Med Chem 108: 623-43 (2016) Article DOI: 10.1016/j.ejmech.2015.12.001 BindingDB Entry DOI: 10.7270/Q2Z60QX5
Semmelweis University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50146591 (CHEMBL3763692) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...				Eur J Med Chem 108: 623-43 (2016) Article DOI: 10.1016/j.ejmech.2015.12.001 BindingDB Entry DOI: 10.7270/Q2Z60QX5
Semmelweis University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50146590 (CHEMBL3765068) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...				Eur J Med Chem 108: 623-43 (2016) Article DOI: 10.1016/j.ejmech.2015.12.001 BindingDB Entry DOI: 10.7270/Q2Z60QX5
Semmelweis University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50146588 (CHEMBL3764145) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...				Eur J Med Chem 108: 623-43 (2016) Article DOI: 10.1016/j.ejmech.2015.12.001 BindingDB Entry DOI: 10.7270/Q2Z60QX5
Semmelweis University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50146587 (CHEMBL3764571) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...				Eur J Med Chem 108: 623-43 (2016) Article DOI: 10.1016/j.ejmech.2015.12.001 BindingDB Entry DOI: 10.7270/Q2Z60QX5
Semmelweis University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A (Homo sapiens (Human))	BDBM50150473 (CHEMBL3769671) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin) by fluorescence assay				Bioorg Med Chem Lett 26: 1498-502 (2016) Article DOI: 10.1016/j.bmcl.2015.06.020 BindingDB Entry DOI: 10.7270/Q2CZ3910
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50146582 (CHEMBL3764712) Show SMILES Cl.NOCCC1Cc2ccccc2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College Curated by ChEMBL					Assay Description Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...				Eur J Med Chem 108: 564-76 (2016) Article DOI: 10.1016/j.ejmech.2015.12.028 BindingDB Entry DOI: 10.7270/Q26Q203T
Bryn Mawr College Curated by ChEMBL					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50146583 (CHEMBL3764480) Show SMILES NOCCCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College Curated by ChEMBL					Assay Description Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...				Eur J Med Chem 108: 564-76 (2016) Article DOI: 10.1016/j.ejmech.2015.12.028 BindingDB Entry DOI: 10.7270/Q26Q203T
Bryn Mawr College Curated by ChEMBL					More data for this Ligand-Target Pair