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1 similar compounds to monomer 50151925

Compile data set for download or QSAR
Wt: 487.6
BDBM50151913

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50151913
PNG
(CHEMBL3774565)
Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)n2nc(nc12)-c1ccccc1
Show InChI InChI=1S/C29H37N5O2/c1-4-5-9-12-33-16-22(25(36)34-26(33)30-23(32-34)21-10-7-6-8-11-21)24(35)31-29-15-20-13-27(2,18-29)17-28(3,14-20)19-29/h6-8,10-11,16,20H,4-5,9,12-15,17-19H2,1-3H3,(H,31,35)
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8.40n/an/an/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes after 60 mins by scintillation counting analysis


Eur J Med Chem 113: 11-27 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.032
BindingDB Entry DOI: 10.7270/Q21J9CPC
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50151913
PNG
(CHEMBL3774565)
Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)n2nc(nc12)-c1ccccc1
Show InChI InChI=1S/C29H37N5O2/c1-4-5-9-12-33-16-22(25(36)34-26(33)30-23(32-34)21-10-7-6-8-11-21)24(35)31-29-15-20-13-27(2,18-29)17-28(3,14-20)19-29/h6-8,10-11,16,20H,4-5,9,12-15,17-19H2,1-3H3,(H,31,35)
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PubMed
653n/an/an/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55,940 from human CB1 receptor expressed in CHO cell membranes after 90 mins by scintillation counting analysis


Eur J Med Chem 113: 11-27 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.032
BindingDB Entry DOI: 10.7270/Q21J9CPC
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50151913
PNG
(CHEMBL3774565)
Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)n2nc(nc12)-c1ccccc1
Show InChI InChI=1S/C29H37N5O2/c1-4-5-9-12-33-16-22(25(36)34-26(33)30-23(32-34)21-10-7-6-8-11-21)24(35)31-29-15-20-13-27(2,18-29)17-28(3,14-20)19-29/h6-8,10-11,16,20H,4-5,9,12-15,17-19H2,1-3H3,(H,31,35)
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n/an/a 18n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of WIN 55,212-2 mediated suppression of forksolin induced c...


Eur J Med Chem 113: 11-27 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.032
BindingDB Entry DOI: 10.7270/Q21J9CPC
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50151913
PNG
(CHEMBL3774565)
Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)n2nc(nc12)-c1ccccc1
Show InChI InChI=1S/C29H37N5O2/c1-4-5-9-12-33-16-22(25(36)34-26(33)30-23(32-34)21-10-7-6-8-11-21)24(35)31-29-15-20-13-27(2,18-29)17-28(3,14-20)19-29/h6-8,10-11,16,20H,4-5,9,12-15,17-19H2,1-3H3,(H,31,35)
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PubMed
n/an/an/an/a 489n/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inverse agonist activity at human CB2 receptor transfected in CHO cells assessed as increase in forksolin stimulated cAMP production by scintillation...


Eur J Med Chem 113: 11-27 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.032
BindingDB Entry DOI: 10.7270/Q21J9CPC
More data for this
Ligand-Target Pair