BindingDB logo
myBDB logout

11 similar compounds to monomer 50151962

Compile data set for download or QSAR
Wt: 393.5
BDBM50151935
Wt: 407.5
BDBM50151942
Wt: 419.5
BDBM50151951
Wt: 407.5
BDBM50151953
Wt: 418.5
BDBM50151958
Wt: 447.6
BDBM50151967
Wt: 449.6
BDBM50151968
Wt: 463.6
BDBM50151970
Wt: 437.5
BDBM50151975
Wt: 421.5
BDBM50151977
Wt: 400.5
BDBM50152017

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50151935,50151942,50151951,50151953,50151958,50151967,50151968,50151970,50151975,50151977,50152017   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50151942
PNG
(5-Ethoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl...)
Show SMILES CCOc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC)cc3)c2c1
Show InChI InChI=1S/C25H33N3O2/c1-3-30-23-11-12-25-24(18-23)20(19-26-25)6-4-5-13-27-14-16-28(17-15-27)21-7-9-22(29-2)10-8-21/h7-12,18-19,26H,3-6,13-17H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-1


(Homo sapiens (Human))
BDBM50151935
PNG
(5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-y...)
Show SMILES COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1
Show InChI InChI=1S/C24H31N3O2/c1-28-21-8-6-20(7-9-21)27-15-13-26(14-16-27)12-4-3-5-19-18-25-24-11-10-22(29-2)17-23(19)24/h6-11,17-18,25H,3-5,12-16H2,1-2H3
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Factor Xa


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50151953
PNG
(3-{4-[4-(4-Ethoxy-phenyl)-piperazin-1-yl]-butyl}-5...)
Show SMILES CCOc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1
Show InChI InChI=1S/C25H33N3O2/c1-3-30-22-9-7-21(8-10-22)28-16-14-27(15-17-28)13-5-4-6-20-19-26-25-12-11-23(29-2)18-24(20)25/h7-12,18-19,26H,3-6,13-17H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151942
PNG
(5-Ethoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl...)
Show SMILES CCOc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC)cc3)c2c1
Show InChI InChI=1S/C25H33N3O2/c1-3-30-23-11-12-25-24(18-23)20(19-26-25)6-4-5-13-27-14-16-28(17-15-27)21-7-9-22(29-2)10-8-21/h7-12,18-19,26H,3-6,13-17H2,1-2H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151958
PNG
(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Show SMILES NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1
Show InChI InChI=1S/C25H30N4O2/c26-25(30)19-4-6-23-22(16-19)20(17-27-23)3-1-2-9-28-10-12-29(13-11-28)21-5-7-24-18(15-21)8-14-31-24/h4-7,15-17,27H,1-3,8-14H2,(H2,26,30)
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151953
PNG
(3-{4-[4-(4-Ethoxy-phenyl)-piperazin-1-yl]-butyl}-5...)
Show SMILES CCOc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1
Show InChI InChI=1S/C25H33N3O2/c1-3-30-22-9-7-21(8-10-22)28-16-14-27(15-17-28)13-5-4-6-20-19-26-25-12-11-23(29-2)18-24(20)25/h7-12,18-19,26H,3-6,13-17H2,1-2H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.800n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151951
PNG
(3-[4-(4-Chroman-6-yl-piperazin-1-yl)-butyl]-5-meth...)
Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCCc4c3)c2c1
Show InChI InChI=1S/C26H33N3O2/c1-30-23-8-9-25-24(18-23)21(19-27-25)5-2-3-11-28-12-14-29(15-13-28)22-7-10-26-20(17-22)6-4-16-31-26/h7-10,17-19,27H,2-6,11-16H2,1H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151935
PNG
(5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-y...)
Show SMILES COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1
Show InChI InChI=1S/C24H31N3O2/c1-28-21-8-6-20(7-9-21)27-15-13-26(14-16-27)12-4-3-5-19-18-25-24-11-10-22(29-2)17-23(19)24/h6-11,17-18,25H,3-5,12-16H2,1-2H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50151967
PNG
(5-Cyclopentyloxy-3-{4-[4-(4-methoxy-phenyl)-pipera...)
Show SMILES COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC4CCCC4)cc23)CC1
Show InChI InChI=1S/C28H37N3O2/c1-32-24-11-9-23(10-12-24)31-18-16-30(17-19-31)15-5-4-6-22-21-29-28-14-13-26(20-27(22)28)33-25-7-2-3-8-25/h9-14,20-21,25,29H,2-8,15-19H2,1H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50151968
PNG
(3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES CCCCCOc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC)cc3)c2c1
Show InChI InChI=1S/C28H39N3O2/c1-3-4-7-20-33-26-13-14-28-27(21-26)23(22-29-28)8-5-6-15-30-16-18-31(19-17-30)24-9-11-25(32-2)12-10-24/h9-14,21-22,29H,3-8,15-20H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151970
PNG
(2,2-Dimethyl-propionic acid 4-{4-[4-(5-methoxy-1H-...)
Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC(=O)C(C)(C)C)cc3)c2c1
Show InChI InChI=1S/C28H37N3O3/c1-28(2,3)27(32)34-23-10-8-22(9-11-23)31-17-15-30(16-18-31)14-6-5-7-21-20-29-26-13-12-24(33-4)19-25(21)26/h8-13,19-20,29H,5-7,14-18H2,1-4H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151967
PNG
(5-Cyclopentyloxy-3-{4-[4-(4-methoxy-phenyl)-pipera...)
Show SMILES COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC4CCCC4)cc23)CC1
Show InChI InChI=1S/C28H37N3O2/c1-32-24-11-9-23(10-12-24)31-18-16-30(17-19-31)15-5-4-6-22-21-29-28-14-13-26(20-27(22)28)33-25-7-2-3-8-25/h9-14,20-21,25,29H,2-8,15-19H2,1H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50151935
PNG
(5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-y...)
Show SMILES COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1
Show InChI InChI=1S/C24H31N3O2/c1-28-21-8-6-20(7-9-21)27-15-13-26(14-16-27)12-4-3-5-19-18-25-24-11-10-22(29-2)17-23(19)24/h6-11,17-18,25H,3-5,12-16H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151975
PNG
(5-Methoxy-3-(4-{4-[4-(2-methoxy-ethoxy)-phenyl]-pi...)
Show SMILES COCCOc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1
Show InChI InChI=1S/C26H35N3O3/c1-30-17-18-32-23-8-6-22(7-9-23)29-15-13-28(14-16-29)12-4-3-5-21-20-27-26-11-10-24(31-2)19-25(21)26/h6-11,19-20,27H,3-5,12-18H2,1-2H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151968
PNG
(3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES CCCCCOc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC)cc3)c2c1
Show InChI InChI=1S/C28H39N3O2/c1-3-4-7-20-33-26-13-14-28-27(21-26)23(22-29-28)8-5-6-15-30-16-18-31(19-17-30)24-9-11-25(32-2)12-10-24/h9-14,21-22,29H,3-8,15-20H2,1-2H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50151977
PNG
(5-Methoxy-3-{4-[4-(4-methoxy-3,5-dimethyl-phenyl)-...)
Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3cc(C)c(OC)c(C)c3)c2c1
Show InChI InChI=1S/C26H35N3O2/c1-19-15-22(16-20(2)26(19)31-4)29-13-11-28(12-14-29)10-6-5-7-21-18-27-25-9-8-23(30-3)17-24(21)25/h8-9,15-18,27H,5-7,10-14H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50151977
PNG
(5-Methoxy-3-{4-[4-(4-methoxy-3,5-dimethyl-phenyl)-...)
Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3cc(C)c(OC)c(C)c3)c2c1
Show InChI InChI=1S/C26H35N3O2/c1-19-15-22(16-20(2)26(19)31-4)29-13-11-28(12-14-29)10-6-5-7-21-18-27-25-9-8-23(30-3)17-24(21)25/h8-9,15-18,27H,5-7,10-14H2,1-4H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50151958
PNG
(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Show SMILES NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1
Show InChI InChI=1S/C25H30N4O2/c26-25(30)19-4-6-23-22(16-19)20(17-27-23)3-1-2-9-28-10-12-29(13-11-28)21-5-7-24-18(15-21)8-14-31-24/h4-7,15-17,27H,1-3,8-14H2,(H2,26,30)
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50152017
PNG
(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Show SMILES N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1
Show InChI InChI=1S/C25H28N4O/c26-17-19-4-6-24-23(15-19)21(18-27-24)3-1-2-9-28-10-12-29(13-11-28)22-5-7-25-20(16-22)8-14-30-25/h4-7,15-16,18,27H,1-3,8-14H2
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4684-92 (2004)


Article DOI: 10.1021/jm040793q
BindingDB Entry DOI: 10.7270/Q2513XPS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50152017
PNG
(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Show SMILES N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1
Show InChI InChI=1S/C25H28N4O/c26-17-19-4-6-24-23(15-19)21(18-27-24)3-1-2-9-28-10-12-29(13-11-28)22-5-7-25-20(16-22)8-14-30-25/h4-7,15-16,18,27H,1-3,8-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-5-HT re-uptake in rat synaptosomes


J Med Chem 47: 4684-92 (2004)


Article DOI: 10.1021/jm040793q
BindingDB Entry DOI: 10.7270/Q2513XPS
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50152017
PNG
(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Show SMILES N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1
Show InChI InChI=1S/C25H28N4O/c26-17-19-4-6-24-23(15-19)21(18-27-24)3-1-2-9-28-10-12-29(13-11-28)22-5-7-25-20(16-22)8-14-30-25/h4-7,15-16,18,27H,1-3,8-14H2
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 8-OH DPAT binding to rat hydroxytryptamine 1A receptor expresssed in CHO cells


J Med Chem 47: 4684-92 (2004)


Article DOI: 10.1021/jm040793q
BindingDB Entry DOI: 10.7270/Q2513XPS
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(Homo sapiens (Human))
BDBM50151935
PNG
(5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-y...)
Show SMILES COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1
Show InChI InChI=1S/C24H31N3O2/c1-28-21-8-6-20(7-9-21)27-15-13-26(14-16-27)12-4-3-5-19-18-25-24-11-10-22(29-2)17-23(19)24/h6-11,17-18,25H,3-5,12-16H2,1-2H3
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Factor Xa


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50151951
PNG
(3-[4-(4-Chroman-6-yl-piperazin-1-yl)-butyl]-5-meth...)
Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCCc4c3)c2c1
Show InChI InChI=1S/C26H33N3O2/c1-30-23-8-9-25-24(18-23)21(19-27-25)5-2-3-11-28-12-14-29(15-13-28)22-7-10-26-20(17-22)6-4-16-31-26/h7-10,17-19,27H,2-6,11-16H2,1H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes


J Med Chem 47: 4677-83 (2004)


Article DOI: 10.1021/jm040792y
BindingDB Entry DOI: 10.7270/Q28S4PCR
More data for this
Ligand-Target Pair