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24 similar compounds to monomer 50156616

Compile data set for download or QSAR
Wt: 497.5
BDBM50156668
Wt: 447.4
BDBM50156627
Wt: 497.5
BDBM50156633
Wt: 369.4
BDBM50156635
Wt: 464.4
BDBM50156638
Wt: 464.4
BDBM50156640
Wt: 476.5
BDBM50156641
Wt: 497.5
BDBM50156643
Wt: 497.5
BDBM50156646
Wt: 464.4
BDBM50156655
Wt: 370.4
BDBM50156656
Wt: 447.4
BDBM50156661
Wt: 446.5
BDBM50156666
Wt: 446.5
BDBM50156599
Wt: 447.4
BDBM50156600
Displayed 1 to 15 (of 24 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50156668,50156627,50156633,50156635,50156638,50156640,50156641,50156643,50156646,50156655,50156656,50156661,50156666,50156599,50156600   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156646
PNG
(2-(furan-2-yl)-5-((7S,9aS)-7-((quinolin-6-yloxy)me...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccc4ncccc4c3)CC[C@H]2C1
Show InChI InChI=1/C26H27N9O2/c27-24-30-25(31-26-29-23(32-35(24)26)22-4-2-12-36-22)34-11-10-33-14-17(5-6-19(33)15-34)16-37-20-7-8-21-18(13-20)3-1-9-28-21/h1-4,7-9,12-13,17,19H,5-6,10-11,14-16H2,(H2,27,29,30,31,32)/t17-,19-/s2
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0.600n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156638
PNG
((7RS,9aRS)-5-[7-(2-fluoro-phenoxymethyl)-octahydro...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccccc3F)CC[C@H]2C1
Show InChI InChI=1/C23H25FN8O2/c24-17-4-1-2-5-18(17)34-14-15-7-8-16-13-31(10-9-30(16)12-15)22-27-21(25)32-23(28-22)26-20(29-32)19-6-3-11-33-19/h1-6,11,15-16H,7-10,12-14H2,(H2,25,26,27,28,29)/t15-,16-/s2
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0.900n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156635
PNG
(5-((7S,9aS)-7-(aminomethyl)-hexahydro-1H-pyrido[1,...)
Show SMILES NC[C@@H]1CC[C@H]2CN(CCN2C1)c1nc(N)n2nc(nc2n1)-c1ccco1
Show InChI InChI=1/C17H23N9O/c18-8-11-3-4-12-10-25(6-5-24(12)9-11)16-21-15(19)26-17(22-16)20-14(23-26)13-2-1-7-27-13/h1-2,7,11-12H,3-6,8-10,18H2,(H2,19,20,21,22,23)/t11-,12-/s2
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2n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156640
PNG
((7RS,9aRS)-5-[7-(3-fluoro-phenoxymethyl)-octahydro...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccc(F)cc3)CC[C@H]2C1
Show InChI InChI=1/C23H25FN8O2/c24-16-4-7-18(8-5-16)34-14-15-3-6-17-13-31(10-9-30(17)12-15)22-27-21(25)32-23(28-22)26-20(29-32)19-2-1-11-33-19/h1-2,4-5,7-8,11,15,17H,3,6,9-10,12-14H2,(H2,25,26,27,28,29)/t15-,17-/s2
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4n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156633
PNG
((7RS,9aRS)-2-furan-2-yl-5-[7-(isoquinolin-5-yloxym...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3cccc4cnccc34)CC[C@H]2C1
Show InChI InChI=1/C26H27N9O2/c27-24-30-25(31-26-29-23(32-35(24)26)22-5-2-12-36-22)34-11-10-33-14-17(6-7-19(33)15-34)16-37-21-4-1-3-18-13-28-9-8-20(18)21/h1-5,8-9,12-13,17,19H,6-7,10-11,14-16H2,(H2,27,29,30,31,32)/t17-,19-/s2
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6n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156643
PNG
(2-(furan-2-yl)-5-((7R,9aS)-7-((quinolin-2-yloxy)me...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](COc3ccc4ccccc4n3)CC[C@H]2C1
Show InChI InChI=1/C26H27N9O2/c27-24-30-25(31-26-29-23(32-35(24)26)21-6-3-13-36-21)34-12-11-33-14-17(7-9-19(33)15-34)16-37-22-10-8-18-4-1-2-5-20(18)28-22/h1-6,8,10,13,17,19H,7,9,11-12,14-16H2,(H2,27,29,30,31,32)/t17-,19+/s2
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7n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156599
PNG
((6RS,9aRS)-2-furan-2-yl-5-(6-phenoxymethyl-octahyd...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2[C@@H](COc3ccccc3)CCC[C@H]2C1
Show InChI InChI=1/C23H26N8O2/c24-21-26-22(27-23-25-20(28-31(21)23)19-10-5-13-32-19)29-11-12-30-16(14-29)6-4-7-17(30)15-33-18-8-2-1-3-9-18/h1-3,5,8-10,13,16-17H,4,6-7,11-12,14-15H2,(H2,24,25,26,27,28)/t16-,17+/s2
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13n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156627
PNG
((7RS,9aRS)-2-furan-2-yl-5-[7-(pyridin-2-yloxymethy...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccccn3)CC[C@H]2C1
Show InChI InChI=1/C22H25N9O2/c23-20-26-21(27-22-25-19(28-31(20)22)17-4-3-11-32-17)30-10-9-29-12-15(6-7-16(29)13-30)14-33-18-5-1-2-8-24-18/h1-5,8,11,15-16H,6-7,9-10,12-14H2,(H2,23,25,26,27,28)/t15-,16-/s2
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20n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156666
PNG
((7RS,9aRS)-2-furan-2-yl-5-[7-(quinolin-6-yloxymeth...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccccc3)CC[C@H]2C1
Show InChI InChI=1/C23H26N8O2/c24-21-26-22(27-23-25-20(28-31(21)23)19-7-4-12-32-19)30-11-10-29-13-16(8-9-17(29)14-30)15-33-18-5-2-1-3-6-18/h1-7,12,16-17H,8-11,13-15H2,(H2,24,25,26,27,28)/t16-,17-/s2
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21n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156668
PNG
((7RS,9aRS)-2-furan-2-yl-5-[7-(isoquinolin-3-yloxym...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3cc4ccccc4cn3)CC[C@H]2C1
Show InChI InChI=1/C26H27N9O2/c27-24-30-25(31-26-29-23(32-35(24)26)21-6-3-11-36-21)34-10-9-33-14-17(7-8-20(33)15-34)16-37-22-12-18-4-1-2-5-19(18)13-28-22/h1-6,11-13,17,20H,7-10,14-16H2,(H2,27,29,30,31,32)/t17-,20-/s2
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36n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156661
PNG
((7RS,9aSR)-2-furan-2-yl-5-[7-(pyridin-2-yloxymethy...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](COc3ccccn3)CC[C@H]2C1
Show InChI InChI=1/C22H25N9O2/c23-20-26-21(27-22-25-19(28-31(20)22)17-4-3-11-32-17)30-10-9-29-12-15(6-7-16(29)13-30)14-33-18-5-1-2-8-24-18/h1-5,8,11,15-16H,6-7,9-10,12-14H2,(H2,23,25,26,27,28)/t15-,16+/s2
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41n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156655
PNG
((7RS,9aSR)-5-[7-(3-fluoro-phenoxymethyl)-octahydro...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](COc3cccc(F)c3)CC[C@H]2C1
Show InChI InChI=1/C23H25FN8O2/c24-16-3-1-4-18(11-16)34-14-15-6-7-17-13-31(9-8-30(17)12-15)22-27-21(25)32-23(28-22)26-20(29-32)19-5-2-10-33-19/h1-5,10-11,15,17H,6-9,12-14H2,(H2,25,26,27,28,29)/t15-,17+/s2
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53n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156641
PNG
((7RS,9aSR)-2-furan-2-yl-5-[7-(4-methoxy-phenoxymet...)
Show SMILES COc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2nc(N)n3nc(nc3n2)-c2ccco2)cc1
Show InChI InChI=1/C24H28N8O3/c1-33-18-6-8-19(9-7-18)35-15-16-4-5-17-14-31(11-10-30(17)13-16)23-27-22(25)32-24(28-23)26-21(29-32)20-3-2-12-34-20/h2-3,6-9,12,16-17H,4-5,10-11,13-15H2,1H3,(H2,25,26,27,28,29)/t16-,17+/s2
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70n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156656
PNG
((7RS,9aSR)-[2-(7-amino-2-furan-2-yl[1,2,4]triazolo...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](CO)CC[C@H]2C1
Show InChI InChI=1/C17H22N8O2/c18-15-20-16(21-17-19-14(22-25(15)17)13-2-1-7-27-13)24-6-5-23-8-11(10-26)3-4-12(23)9-24/h1-2,7,11-12,26H,3-6,8-10H2,(H2,18,19,20,21,22)/t11-,12+/s2
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71n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50156600
PNG
((7RS,9aSR)-2-furan-2-yl-5-[7-(pyridin-4-yloxymethy...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](COc3ccncc3)CC[C@H]2C1
Show InChI InChI=1/C22H25N9O2/c23-20-26-21(27-22-25-19(28-31(20)22)18-2-1-11-32-18)30-10-9-29-12-15(3-4-16(29)13-30)14-33-17-5-7-24-8-6-17/h1-2,5-8,11,15-16H,3-4,9-10,12-14H2,(H2,23,25,26,27,28)/t15-,16+/s2
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81n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156641
PNG
((7RS,9aSR)-2-furan-2-yl-5-[7-(4-methoxy-phenoxymet...)
Show SMILES COc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2nc(N)n3nc(nc3n2)-c2ccco2)cc1
Show InChI InChI=1/C24H28N8O3/c1-33-18-6-8-19(9-7-18)35-15-16-4-5-17-14-31(11-10-30(17)13-16)23-27-22(25)32-24(28-23)26-21(29-32)20-3-2-12-34-20/h2-3,6-9,12,16-17H,4-5,10-11,13-15H2,1H3,(H2,25,26,27,28,29)/t16-,17+/s2
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>500n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156599
PNG
((6RS,9aRS)-2-furan-2-yl-5-(6-phenoxymethyl-octahyd...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2[C@@H](COc3ccccc3)CCC[C@H]2C1
Show InChI InChI=1/C23H26N8O2/c24-21-26-22(27-23-25-20(28-31(21)23)19-10-5-13-32-19)29-11-12-30-16(14-29)6-4-7-17(30)15-33-18-8-2-1-3-9-18/h1-3,5,8-10,13,16-17H,4,6-7,11-12,14-15H2,(H2,24,25,26,27,28)/t16-,17+/s2
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>500n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156661
PNG
((7RS,9aSR)-2-furan-2-yl-5-[7-(pyridin-2-yloxymethy...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](COc3ccccn3)CC[C@H]2C1
Show InChI InChI=1/C22H25N9O2/c23-20-26-21(27-22-25-19(28-31(20)22)17-4-3-11-32-17)30-10-9-29-12-15(6-7-16(29)13-30)14-33-18-5-1-2-8-24-18/h1-5,8,11,15-16H,6-7,9-10,12-14H2,(H2,23,25,26,27,28)/t15-,16+/s2
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>500n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156666
PNG
((7RS,9aRS)-2-furan-2-yl-5-[7-(quinolin-6-yloxymeth...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccccc3)CC[C@H]2C1
Show InChI InChI=1/C23H26N8O2/c24-21-26-22(27-23-25-20(28-31(21)23)19-7-4-12-32-19)30-11-10-29-13-16(8-9-17(29)14-30)15-33-18-5-2-1-3-6-18/h1-7,12,16-17H,8-11,13-15H2,(H2,24,25,26,27,28)/t16-,17-/s2
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>500n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156640
PNG
((7RS,9aRS)-5-[7-(3-fluoro-phenoxymethyl)-octahydro...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccc(F)cc3)CC[C@H]2C1
Show InChI InChI=1/C23H25FN8O2/c24-16-4-7-18(8-5-16)34-14-15-3-6-17-13-31(10-9-30(17)12-15)22-27-21(25)32-23(28-22)26-20(29-32)19-2-1-11-33-19/h1-2,4-5,7-8,11,15,17H,3,6,9-10,12-14H2,(H2,25,26,27,28,29)/t15-,17-/s2
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>500n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156638
PNG
((7RS,9aRS)-5-[7-(2-fluoro-phenoxymethyl)-octahydro...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccccc3F)CC[C@H]2C1
Show InChI InChI=1/C23H25FN8O2/c24-17-4-1-2-5-18(17)34-14-15-7-8-16-13-31(10-9-30(16)12-15)22-27-21(25)32-23(28-22)26-20(29-32)19-6-3-11-33-19/h1-6,11,15-16H,7-10,12-14H2,(H2,25,26,27,28,29)/t15-,16-/s2
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>500n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156655
PNG
((7RS,9aSR)-5-[7-(3-fluoro-phenoxymethyl)-octahydro...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](COc3cccc(F)c3)CC[C@H]2C1
Show InChI InChI=1/C23H25FN8O2/c24-16-3-1-4-18(11-16)34-14-15-6-7-17-13-31(9-8-30(17)12-15)22-27-21(25)32-23(28-22)26-20(29-32)19-5-2-10-33-19/h1-5,10-11,15,17H,6-9,12-14H2,(H2,25,26,27,28,29)/t15-,17+/s2
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960n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156627
PNG
((7RS,9aRS)-2-furan-2-yl-5-[7-(pyridin-2-yloxymethy...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccccn3)CC[C@H]2C1
Show InChI InChI=1/C22H25N9O2/c23-20-26-21(27-22-25-19(28-31(20)22)17-4-3-11-32-17)30-10-9-29-12-15(6-7-16(29)13-30)14-33-18-5-1-2-8-24-18/h1-5,8,11,15-16H,6-7,9-10,12-14H2,(H2,23,25,26,27,28)/t15-,16-/s2
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>1.00E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156600
PNG
((7RS,9aSR)-2-furan-2-yl-5-[7-(pyridin-4-yloxymethy...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](COc3ccncc3)CC[C@H]2C1
Show InChI InChI=1/C22H25N9O2/c23-20-26-21(27-22-25-19(28-31(20)22)18-2-1-11-32-18)30-10-9-29-12-15(3-4-16(29)13-30)14-33-17-5-7-24-8-6-17/h1-2,5-8,11,15-16H,3-4,9-10,12-14H2,(H2,23,25,26,27,28)/t15-,16+/s2
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>1.00E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156668
PNG
((7RS,9aRS)-2-furan-2-yl-5-[7-(isoquinolin-3-yloxym...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3cc4ccccc4cn3)CC[C@H]2C1
Show InChI InChI=1/C26H27N9O2/c27-24-30-25(31-26-29-23(32-35(24)26)21-6-3-11-36-21)34-10-9-33-14-17(7-8-20(33)15-34)16-37-22-12-18-4-1-2-5-19(18)13-28-22/h1-6,11-13,17,20H,7-10,14-16H2,(H2,27,29,30,31,32)/t17-,20-/s2
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>1.00E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156643
PNG
(2-(furan-2-yl)-5-((7R,9aS)-7-((quinolin-2-yloxy)me...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](COc3ccc4ccccc4n3)CC[C@H]2C1
Show InChI InChI=1/C26H27N9O2/c27-24-30-25(31-26-29-23(32-35(24)26)21-6-3-13-36-21)34-12-11-33-14-17(7-9-19(33)15-34)16-37-22-10-8-18-4-1-2-5-20(18)28-22/h1-6,8,10,13,17,19H,7,9,11-12,14-16H2,(H2,27,29,30,31,32)/t17-,19+/s2
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>1.00E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156635
PNG
(5-((7S,9aS)-7-(aminomethyl)-hexahydro-1H-pyrido[1,...)
Show SMILES NC[C@@H]1CC[C@H]2CN(CCN2C1)c1nc(N)n2nc(nc2n1)-c1ccco1
Show InChI InChI=1/C17H23N9O/c18-8-11-3-4-12-10-25(6-5-24(12)9-11)16-21-15(19)26-17(22-16)20-14(23-26)13-2-1-7-27-13/h1-2,7,11-12H,3-6,8-10,18H2,(H2,19,20,21,22,23)/t11-,12-/s2
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3.50E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156633
PNG
((7RS,9aRS)-2-furan-2-yl-5-[7-(isoquinolin-5-yloxym...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3cccc4cnccc34)CC[C@H]2C1
Show InChI InChI=1/C26H27N9O2/c27-24-30-25(31-26-29-23(32-35(24)26)22-5-2-12-36-22)34-11-10-33-14-17(6-7-19(33)15-34)16-37-21-4-1-3-18-13-28-9-8-20(18)21/h1-5,8-9,12-13,17,19H,6-7,10-11,14-16H2,(H2,27,29,30,31,32)/t17-,19-/s2
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3.50E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156646
PNG
(2-(furan-2-yl)-5-((7S,9aS)-7-((quinolin-6-yloxy)me...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@@H](COc3ccc4ncccc4c3)CC[C@H]2C1
Show InChI InChI=1/C26H27N9O2/c27-24-30-25(31-26-29-23(32-35(24)26)22-4-2-12-36-22)34-11-10-33-14-17(5-6-19(33)15-34)16-37-20-7-8-21-18(13-20)3-1-9-28-21/h1-4,7-9,12-13,17,19H,5-6,10-11,14-16H2,(H2,27,29,30,31,32)/t17-,19-/s2
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3.50E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50156656
PNG
((7RS,9aSR)-[2-(7-amino-2-furan-2-yl[1,2,4]triazolo...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN2C[C@H](CO)CC[C@H]2C1
Show InChI InChI=1/C17H22N8O2/c18-15-20-16(21-17-19-14(22-25(15)17)13-2-1-7-27-13)24-6-5-23-8-11(10-26)3-4-12(23)9-24/h1-2,7,11-12,26H,3-6,8-10H2,(H2,18,19,20,21,22)/t11-,12+/s2
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6.10E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membrane


J Med Chem 47: 6218-29 (2004)


Article DOI: 10.1021/jm0494321
BindingDB Entry DOI: 10.7270/Q20V8DM9
More data for this
Ligand-Target Pair