BindingDB logo
myBDB logout

5 similar compounds to monomer 50241107

Compile data set for download or QSAR
Wt: 342.4
BDBM50187756
Wt: 438.9
BDBM50263837
Wt: 424.9
BDBM50263889
Wt: 307.8
BDBM50401408
Wt: 293.7
BDBM50401403

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50187756,50263837,50263889,50401408,50401403   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha adrenergic receptor 1A and 1B


(Rattus norvegicus (rat))
BDBM50187756
PNG
(1-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)
Show SMILES O=c1[nH]c2ccccc2n1C1CCN(CCCN2CCCCC2)CC1
Show InChI InChI=1S/C20H30N4O/c25-20-21-18-7-2-3-8-19(18)24(20)17-9-15-23(16-10-17)14-6-13-22-11-4-1-5-12-22/h2-3,7-8,17H,1,4-6,9-16H2,(H,21,25)
Reactome pathway

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
70n/an/an/an/an/an/an/an/a



Toray Industries, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes


Bioorg Med Chem Lett 16: 4045-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.002
BindingDB Entry DOI: 10.7270/Q2514001
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
371n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]methylspiperone from human low affinity Dopamine D2S receptor by competition binding assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
456n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]7-OH-DPAT from human high affinity Dopamine D2S receptor by competition binding assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50187756
PNG
(1-(1-(3-(piperidin-1-yl)propyl)piperidin-4-yl)-1H-...)
Show SMILES O=c1[nH]c2ccccc2n1C1CCN(CCCN2CCCCC2)CC1
Show InChI InChI=1S/C20H30N4O/c25-20-21-18-7-2-3-8-19(18)24(20)17-9-15-23(16-10-17)14-6-13-22-11-4-1-5-12-22/h2-3,7-8,17H,1,4-6,9-16H2,(H,21,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
900n/an/an/an/an/an/an/an/a



Toray Industries, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes


Bioorg Med Chem Lett 16: 4045-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.002
BindingDB Entry DOI: 10.7270/Q2514001
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50401408
PNG
(CHEMBL2207494)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2n(C)c1=O
Show InChI InChI=1S/C16H22ClN3O/c1-3-8-19-9-6-13(7-10-19)20-14-5-4-12(17)11-15(14)18(2)16(20)21/h4-5,11,13H,3,6-10H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.00E+3n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]methylspiperone from human low affinity Dopamine D2S receptor by competition binding assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50401408
PNG
(CHEMBL2207494)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2n(C)c1=O
Show InChI InChI=1S/C16H22ClN3O/c1-3-8-19-9-6-13(7-10-19)20-14-5-4-12(17)11-15(14)18(2)16(20)21/h4-5,11,13H,3,6-10H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.24E+3n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]imipramine from human SERT expressed in CHO cells by competition binding assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.52E+3n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]7-OH-DPAT from human dopamine D3 receptor by CEREP assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.51E+3n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]imipramine from human SERT expressed in CHO cells by competition binding assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50401408
PNG
(CHEMBL2207494)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2n(C)c1=O
Show InChI InChI=1S/C16H22ClN3O/c1-3-8-19-9-6-13(7-10-19)20-14-5-4-12(17)11-15(14)18(2)16(20)21/h4-5,11,13H,3,6-10H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.18E+3n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]7-OH-DPAT from human high affinity Dopamine D2S receptor by competition binding assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.71E+3n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]8- OH-DPAT from human 5-HT1A by CEREP assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.72E+4n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]UK 14.304 from human adrenergic alpha2A receptor


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
Reactome pathway
KEGG

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.16E+4n/an/an/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from human 5-HT2A by CEREP assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))
BDBM50263889
PNG
(1-(1'-Benzyl-[1,4']bipiperidinyl-4-yl)-5-chloro-1,...)
Show SMILES Clc1ccc2n(C3CCN(CC3)C3CCN(Cc4ccccc4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H29ClN4O/c25-19-6-7-23-22(16-19)26-24(30)29(23)21-10-14-28(15-11-21)20-8-12-27(13-9-20)17-18-4-2-1-3-5-18/h1-7,16,20-21H,8-15,17H2,(H,26,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M4 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.80E+5n/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50401408
PNG
(CHEMBL2207494)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2n(C)c1=O
Show InChI InChI=1S/C16H22ClN3O/c1-3-8-19-9-6-13(7-10-19)20-14-5-4-12(17)11-15(14)18(2)16(20)21/h4-5,11,13H,3,6-10H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.80E+5n/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 41-1049 from MAO-A in rat cerebral cortex by competition binding assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50401403
PNG
(CHEMBL2207493)
Show SMILES CCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C15H20ClN3O/c1-2-7-18-8-5-12(6-9-18)19-14-4-3-11(16)10-13(14)17-15(19)20/h3-4,10,12H,2,5-9H2,1H3,(H,17,20)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.80E+5n/an/an/an/an/an/a



NeuroSearch Sweden AB

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 41-1049 from MAO-A in rat cerebral cortex by competition binding assay


J Med Chem 55: 9735-50 (2012)


Article DOI: 10.1021/jm300975f
BindingDB Entry DOI: 10.7270/Q26974RR
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50263837
PNG
(5-Chloro-1-[1'-(2-methyl-benzyl)-[1,4']bipiperidin...)
Show SMILES Cc1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C25H31ClN4O/c1-18-4-2-3-5-19(18)17-28-12-8-21(9-13-28)29-14-10-22(11-15-29)30-24-7-6-20(26)16-23(24)27-25(30)31/h2-7,16,21-22H,8-15,17H2,1H3,(H,27,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M3 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50263889
PNG
(1-(1'-Benzyl-[1,4']bipiperidinyl-4-yl)-5-chloro-1,...)
Show SMILES Clc1ccc2n(C3CCN(CC3)C3CCN(Cc4ccccc4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H29ClN4O/c25-19-6-7-23-22(16-19)26-24(30)29(23)21-10-14-28(15-11-21)20-8-12-27(13-9-20)17-18-4-2-1-3-5-18/h1-7,16,20-21H,8-15,17H2,(H,26,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M3 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50263837
PNG
(5-Chloro-1-[1'-(2-methyl-benzyl)-[1,4']bipiperidin...)
Show SMILES Cc1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C25H31ClN4O/c1-18-4-2-3-5-19(18)17-28-12-8-21(9-13-28)29-14-10-22(11-15-29)30-24-7-6-20(26)16-23(24)27-25(30)31/h2-7,16,21-22H,8-15,17H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M2 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50263889
PNG
(1-(1'-Benzyl-[1,4']bipiperidinyl-4-yl)-5-chloro-1,...)
Show SMILES Clc1ccc2n(C3CCN(CC3)C3CCN(Cc4ccccc4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H29ClN4O/c25-19-6-7-23-22(16-19)26-24(30)29(23)21-10-14-28(15-11-21)20-8-12-27(13-9-20)17-18-4-2-1-3-5-18/h1-7,16,20-21H,8-15,17H2,(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M2 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M5 chimeric protein


(Homo sapiens (Human))
BDBM50263837
PNG
(5-Chloro-1-[1'-(2-methyl-benzyl)-[1,4']bipiperidin...)
Show SMILES Cc1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C25H31ClN4O/c1-18-4-2-3-5-19(18)17-28-12-8-21(9-13-28)29-14-10-22(11-15-29)30-24-7-6-20(26)16-23(24)27-25(30)31/h2-7,16,21-22H,8-15,17H2,1H3,(H,27,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M5 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M5 chimeric protein


(Homo sapiens (Human))
BDBM50263889
PNG
(1-(1'-Benzyl-[1,4']bipiperidinyl-4-yl)-5-chloro-1,...)
Show SMILES Clc1ccc2n(C3CCN(CC3)C3CCN(Cc4ccccc4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H29ClN4O/c25-19-6-7-23-22(16-19)26-24(30)29(23)21-10-14-28(15-11-21)20-8-12-27(13-9-20)17-18-4-2-1-3-5-18/h1-7,16,20-21H,8-15,17H2,(H,26,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M5 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50263837
PNG
(5-Chloro-1-[1'-(2-methyl-benzyl)-[1,4']bipiperidin...)
Show SMILES Cc1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C25H31ClN4O/c1-18-4-2-3-5-19(18)17-28-12-8-21(9-13-28)29-14-10-22(11-15-29)30-24-7-6-20(26)16-23(24)27-25(30)31/h2-7,16,21-22H,8-15,17H2,1H3,(H,27,31)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.03E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M1 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50263889
PNG
(1-(1'-Benzyl-[1,4']bipiperidinyl-4-yl)-5-chloro-1,...)
Show SMILES Clc1ccc2n(C3CCN(CC3)C3CCN(Cc4ccccc4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H29ClN4O/c25-19-6-7-23-22(16-19)26-24(30)29(23)21-10-14-28(15-11-21)20-8-12-27(13-9-20)17-18-4-2-1-3-5-18/h1-7,16,20-21H,8-15,17H2,(H,26,30)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 356n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M1 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))
BDBM50263837
PNG
(5-Chloro-1-[1'-(2-methyl-benzyl)-[1,4']bipiperidin...)
Show SMILES Cc1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C25H31ClN4O/c1-18-4-2-3-5-19(18)17-28-12-8-21(9-13-28)29-14-10-22(11-15-29)30-24-7-6-20(26)16-23(24)27-25(30)31/h2-7,16,21-22H,8-15,17H2,1H3,(H,27,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at muscarinic M4 receptor (unknown origin)


Bioorg Med Chem Lett 18: 5439-42 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.023
BindingDB Entry DOI: 10.7270/Q2708198
More data for this
Ligand-Target Pair