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2 similar compounds to monomer 50200390

Compile data set for download or QSAR
Wt: 274.2
BDBM50200388

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200388   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM50200388
PNG
(CHEMBL3908519)
Show SMILES CC(=O)N1CCc2[nH]nc(Nc3cccc(F)c3)c2C1
Show InChI InChI=1S/C14H15FN4O/c1-9(20)19-6-5-13-12(8-19)14(18-17-13)16-11-4-2-3-10(15)7-11/h2-4,7H,5-6,8H2,1H3,(H2,16,17,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Displacement of biotinylated ligand from recombinant His-tagged BRD4 bromodomain-1 (unknown origin) measured after 10 mins by TR-FRET assay


J Med Chem 59: 10549-10563 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01022
BindingDB Entry DOI: 10.7270/Q27083DF
More data for this
Ligand-Target Pair
CREB-binding protein/Histone acetyltransferase p300


(Homo sapiens (Human))
BDBM50200388
PNG
(CHEMBL3908519)
Show SMILES CC(=O)N1CCc2[nH]nc(Nc3cccc(F)c3)c2C1
Show InChI InChI=1S/C14H15FN4O/c1-9(20)19-6-5-13-12(8-19)14(18-17-13)16-11-4-2-3-10(15)7-11/h2-4,7H,5-6,8H2,1H3,(H2,16,17,18)
PDB
MMDB

Reactome pathway

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 430n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assay


J Med Chem 59: 10549-10563 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01022
BindingDB Entry DOI: 10.7270/Q27083DF
More data for this
Ligand-Target Pair