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3 similar compounds to monomer 50207811

Wt: 271.2
BDBM50207812
Wt: 271.2
BDBM50207813
Wt: 271.2
BDBM50207810

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50207812,50207813,50207810   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 8 (mGlu8)


(Rattus norvegicus (Rat))
BDBM50207812
PNG
((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@H]1[C@H]([C@@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m1/s1
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1.90E+5n/an/an/an/an/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assay


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50207812
PNG
((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@H]1[C@H]([C@@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m1/s1
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6.30E+5n/an/an/an/an/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50207813
PNG
((2S,1'S,2'R,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8+,9?,10-/m1/s1
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>1.00E+6n/an/an/an/an/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50207810
PNG
((2S,1'S,2'R,3'R)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m0/s1
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>1.00E+6n/an/an/an/an/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2 (mGluR2)


(Homo sapiens (Human))
BDBM50207812
PNG
((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@H]1[C@H]([C@@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m1/s1
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n/an/an/an/a 3.20E+5n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at human recombinant mGluR2 expressed in BHK cells assessed as stimulation of [35S]GTP-gamma-S binding


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 6 (mGlu6)


(Rattus norvegicus (Rat))
BDBM50207813
PNG
((2S,1'S,2'R,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8+,9?,10-/m1/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at rat recombinant mGluR6 expressed in CHO cells assessed as cAMP production


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50207810
PNG
((2S,1'S,2'R,3'R)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m0/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Agonist activity at rat recombinant mGluR4 expressed in BHK cells


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
GRM7


(HUMAN)
BDBM50207813
PNG
((2S,1'S,2'R,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8+,9?,10-/m1/s1
PDB
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at human recombinant mGluR7 expressed in BHK cells assessed as cAMP production


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
metabotropic glutamate 1/2


(RAT)
BDBM50207810
PNG
((2S,1'S,2'R,3'R)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m0/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at rat recombinant mGluR1 expressed in CHO cells assessed as intracellular calcium concentration


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2 (mGluR2)


(Homo sapiens (Human))
BDBM50207813
PNG
((2S,1'S,2'R,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8+,9?,10-/m1/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at human recombinant mGluR2 expressed in BHK cells assessed as stimulation of [35S]GTP-gamma-S binding


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
metabotropic glutamate 1/2


(RAT)
BDBM50207812
PNG
((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@H]1[C@H]([C@@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m1/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at rat recombinant mGluR1 expressed in CHO cells assessed as intracellular calcium concentration


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50207813
PNG
((2S,1'S,2'R,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8+,9?,10-/m1/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at rat recombinant mGluR5 expressed in CHO cells assessed as intracellular calcium concentration


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50207812
PNG
((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@H]1[C@H]([C@@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m1/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at rat recombinant mGluR5 expressed in CHO cells assessed as intracellular calcium concentration


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
metabotropic glutamate 1/2


(RAT)
BDBM50207813
PNG
((2S,1'S,2'R,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8+,9?,10-/m1/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at rat recombinant mGluR1 expressed in CHO cells assessed as intracellular calcium concentration


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50207810
PNG
((2S,1'S,2'R,3'R)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m0/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at rat recombinant mGluR5 expressed in CHO cells assessed as intracellular calcium concentration


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2 (mGluR2)


(Homo sapiens (Human))
BDBM50207810
PNG
((2S,1'S,2'R,3'R)-2-(2'-phosphono-3'-phenylcyclopro...)
Show SMILES NC([C@@H]1[C@@H]([C@H]1P(O)(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8-,9?,10+/m0/s1
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n/an/an/an/a>1.00E+6n/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Activity at human recombinant mGluR2 expressed in BHK cells assessed as stimulation of [35S]GTP-gamma-S binding


Bioorg Med Chem 15: 3161-70 (2007)

More data for this
Ligand-Target Pair