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2 similar compounds to monomer 50209185

Wt: 469.6
BDBM50209180
Wt: 433.2
BDBM50209195

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209180,50209195   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM50209180
PNG
(6-(5-bromo-2-hydroxyphenyl)-4-(2-chloro-5-(trifluo...)
Show SMILES Oc1ccc(Br)cc1-c1cc(-c2cc(ccc2Cl)C(F)(F)F)c(C#N)c(=O)[nH]1
Show InChI InChI=1S/C19H9BrClF3N2O2/c20-10-2-4-17(27)13(6-10)16-7-11(14(8-25)18(28)26-16)12-5-9(19(22,23)24)1-3-15(12)21/h1-7,27H,(H,26,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 490n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins


Bioorg Med Chem Lett 17: 3122-9 (2007)

More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5


(Homo sapiens)
BDBM50209195
PNG
(4-(2,5-dichloro-phenyl)-6-(4-hydroxy-biphenyl-3-yl...)
Show SMILES Oc1ccc(cc1-c1cc(-c2cc(Cl)ccc2Cl)c(C#N)c(=O)[nH]1)-c1ccccc1
Show InChI InChI=1S/C24H14Cl2N2O2/c25-16-7-8-21(26)18(11-16)17-12-22(28-24(30)20(17)13-27)19-10-15(6-9-23(19)29)14-4-2-1-3-5-14/h1-12,29H,(H,28,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 700n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins


Bioorg Med Chem Lett 17: 3122-9 (2007)

More data for this
Ligand-Target Pair