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1 similar compounds to monomer 50234074

Compile data set for download or QSAR
Wt: 309.4
BDBM50214438

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50214438   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 6


(Homo sapiens (Human))
BDBM50214438
PNG
(1-(6-(2-mercaptoacetamido)hexyl)-3-phenylurea | 2-...)
Show SMILES SCC(=O)NCCCCCCNC(=O)Nc1ccccc1
Show InChI InChI=1S/C15H23N3O2S/c19-14(12-21)16-10-6-1-2-7-11-17-15(20)18-13-8-4-3-5-9-13/h3-5,8-9,21H,1-2,6-7,10-12H2,(H,16,19)(H2,17,18,20)
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Article
PubMed
n/an/a 2.01E+3n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assay


J Med Chem 50: 3054-61 (2007)


Article DOI: 10.1021/jm070178x
BindingDB Entry DOI: 10.7270/Q26W99SW
More data for this
Ligand-Target Pair
Histone deacetylase 8


(Homo sapiens (Human))
BDBM50214438
PNG
(1-(6-(2-mercaptoacetamido)hexyl)-3-phenylurea | 2-...)
Show SMILES SCC(=O)NCCCCCCNC(=O)Nc1ccccc1
Show InChI InChI=1S/C15H23N3O2S/c19-14(12-21)16-10-6-1-2-7-11-17-15(20)18-13-8-4-3-5-9-13/h3-5,8-9,21H,1-2,6-7,10-12H2,(H,16,19)(H2,17,18,20)
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Article
PubMed
n/an/a 1.39E+4n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assay


J Med Chem 50: 3054-61 (2007)


Article DOI: 10.1021/jm070178x
BindingDB Entry DOI: 10.7270/Q26W99SW
More data for this
Ligand-Target Pair
Histone Deacetylase 10 (HDAC10)


(Homo sapiens (Human))
BDBM50214438
PNG
(1-(6-(2-mercaptoacetamido)hexyl)-3-phenylurea | 2-...)
Show SMILES SCC(=O)NCCCCCCNC(=O)Nc1ccccc1
Show InChI InChI=1S/C15H23N3O2S/c19-14(12-21)16-10-6-1-2-7-11-17-15(20)18-13-8-4-3-5-9-13/h3-5,8-9,21H,1-2,6-7,10-12H2,(H,16,19)(H2,17,18,20)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assay


J Med Chem 50: 3054-61 (2007)


Article DOI: 10.1021/jm070178x
BindingDB Entry DOI: 10.7270/Q26W99SW
More data for this
Ligand-Target Pair
Histone deacetylase 2


(Homo sapiens (Human))
BDBM50214438
PNG
(1-(6-(2-mercaptoacetamido)hexyl)-3-phenylurea | 2-...)
Show SMILES SCC(=O)NCCCCCCNC(=O)Nc1ccccc1
Show InChI InChI=1S/C15H23N3O2S/c19-14(12-21)16-10-6-1-2-7-11-17-15(20)18-13-8-4-3-5-9-13/h3-5,8-9,21H,1-2,6-7,10-12H2,(H,16,19)(H2,17,18,20)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assay


J Med Chem 50: 3054-61 (2007)


Article DOI: 10.1021/jm070178x
BindingDB Entry DOI: 10.7270/Q26W99SW
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))
BDBM50214438
PNG
(1-(6-(2-mercaptoacetamido)hexyl)-3-phenylurea | 2-...)
Show SMILES SCC(=O)NCCCCCCNC(=O)Nc1ccccc1
Show InChI InChI=1S/C15H23N3O2S/c19-14(12-21)16-10-6-1-2-7-11-17-15(20)18-13-8-4-3-5-9-13/h3-5,8-9,21H,1-2,6-7,10-12H2,(H,16,19)(H2,17,18,20)
PDB
MMDB

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PC sid
UniChem

Patents


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Article
PubMed
n/an/a 1.08E+4n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assay


J Med Chem 50: 3054-61 (2007)


Article DOI: 10.1021/jm070178x
BindingDB Entry DOI: 10.7270/Q26W99SW
More data for this
Ligand-Target Pair