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6 similar compounds to monomer 50230283

Compile data set for download or QSAR
Wt: 195.1
BDBM50227637
Wt: 226.2
BDBM50230280
Wt: 188.2
BDBM50230281
Wt: 256.3
BDBM50230282
Wt: 446.5
BDBM50231606
Wt: 430.5
BDBM50231607

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50227637,50230280,50230281,50230282,50231606,50231607   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50231607
PNG
(CHEMBL127218)
Show SMILES [Na+].CCc1cc(c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1)-c1ccc(C)cc1
Show InChI InChI=1S/C24H31N4O2.Na/c1-5-18-15-20(19-11-9-17(2)10-12-19)21(29)16-22(18)30-14-8-6-7-13-24(3,4)23-25-27-28-26-23;/h9-12,15-16H,5-8,13-14H2,1-4H3,(H-,25,26,27,28,29);/q-1;+1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
37n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]LTB4 receptor binding in guinea pig lung membrane


J Med Chem 36: 3978-81 (1993)


Article DOI: 10.1021/jm00076a029
BindingDB Entry DOI: 10.7270/Q20V8G1H
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50231606
PNG
(CHEMBL128755)
Show SMILES [Na+].CCc1cc(c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1)-c1ccc(OC)cc1
Show InChI InChI=1S/C24H31N4O3.Na/c1-5-17-15-20(18-9-11-19(30-4)12-10-18)21(29)16-22(17)31-14-8-6-7-13-24(2,3)23-25-27-28-26-23;/h9-12,15-16H,5-8,13-14H2,1-4H3,(H-,25,26,27,28,29);/q-1;+1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
55n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]LTB4 receptor binding in guinea pig lung membrane


J Med Chem 36: 3978-81 (1993)


Article DOI: 10.1021/jm00076a029
BindingDB Entry DOI: 10.7270/Q20V8G1H
More data for this
Ligand-Target Pair
Phosphodiesterase 3


(Homo sapiens (Human))
BDBM50230281
PNG
(CHEMBL144682)
Show SMILES CCCc1nccc2nc(O)ccc12
Show InChI InChI=1S/C11H12N2O/c1-2-3-9-8-4-5-11(14)13-10(8)6-7-12-9/h4-7H,2-3H2,1H3,(H,13,14)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 48n/an/an/an/an/an/a



Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against cAMP PDE III.


J Med Chem 35: 4858-65 (1992)


Article DOI: 10.1021/jm00104a012
BindingDB Entry DOI: 10.7270/Q2H13480
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50231606
PNG
(CHEMBL128755)
Show SMILES [Na+].CCc1cc(c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1)-c1ccc(OC)cc1
Show InChI InChI=1S/C24H31N4O3.Na/c1-5-17-15-20(18-9-11-19(30-4)12-10-18)21(29)16-22(17)31-14-8-6-7-13-24(2,3)23-25-27-28-26-23;/h9-12,15-16H,5-8,13-14H2,1-4H3,(H-,25,26,27,28,29);/q-1;+1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]LTB4 receptor binding in human neutrophils


J Med Chem 36: 3978-81 (1993)


Article DOI: 10.1021/jm00076a029
BindingDB Entry DOI: 10.7270/Q20V8G1H
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50231607
PNG
(CHEMBL127218)
Show SMILES [Na+].CCc1cc(c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1)-c1ccc(C)cc1
Show InChI InChI=1S/C24H31N4O2.Na/c1-5-18-15-20(19-11-9-17(2)10-12-19)21(29)16-22(18)30-14-8-6-7-13-24(3,4)23-25-27-28-26-23;/h9-12,15-16H,5-8,13-14H2,1-4H3,(H-,25,26,27,28,29);/q-1;+1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]LTB4 receptor binding in human neutrophils


J Med Chem 36: 3978-81 (1993)


Article DOI: 10.1021/jm00076a029
BindingDB Entry DOI: 10.7270/Q20V8G1H
More data for this
Ligand-Target Pair
Phosphodiesterase 3


(Homo sapiens (Human))
BDBM50230280
PNG
(CHEMBL142834)
Show SMILES Cc1cn(cn1)-c1nccc2nc(O)ccc12
Show InChI InChI=1S/C12H10N4O/c1-8-6-16(7-14-8)12-9-2-3-11(17)15-10(9)4-5-13-12/h2-7H,1H3,(H,15,17)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against cAMP PDE III.


J Med Chem 35: 4858-65 (1992)


Article DOI: 10.1021/jm00104a012
BindingDB Entry DOI: 10.7270/Q2H13480
More data for this
Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase


(Staphylococcus epidermidis (strain ATCC 35984 / RP...)
BDBM50227637
PNG
(CHEMBL3350233)
Show SMILES C[C@@H](N)P(O)(=O)C[C@H](C)C(O)=O
Show InChI InChI=1/C6H14NO4P/c1-4(6(8)9)3-12(10,11)5(2)7/h4-5H,3,7H2,1-2H3,(H,8,9)(H,10,11)/t4-,5-/s2
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Antibacterial activity against D-alanyl-D-alanine ligase from Streptococcus faecalis (ATCC 8043)


J Med Chem 31: 1772-8 (1988)


Article DOI: 10.1021/jm00117a017
BindingDB Entry DOI: 10.7270/Q24B31XZ
More data for this
Ligand-Target Pair
Phosphodiesterase 4


(Homo sapiens (Human))
BDBM50230282
PNG
(CHEMBL143079)
Show SMILES CCCCn1c2ncccc2c2ncn(C)c2c1=O
Show InChI InChI=1S/C14H16N4O/c1-3-4-8-18-13-10(6-5-7-15-13)11-12(14(18)19)17(2)9-16-11/h5-7,9H,3-4,8H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Canine Tracheal Smooth Muscle PDE 4


J Med Chem 35: 4866-74 (1992)


Article DOI: 10.1021/jm00104a013
BindingDB Entry DOI: 10.7270/Q2C82CJ8
More data for this
Ligand-Target Pair