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3 similar compounds to monomer 50229920

Compile data set for download or QSAR
Wt: 303.3
BDBM50229906
Wt: 410.6
BDBM50229918
Wt: 441.7
BDBM50229919

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50229906,50229918,50229919   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor


(Homo sapiens (Human))
BDBM50229906
PNG
(CHEMBL87546 | TCMDC-139337)
Show SMILES Cc1cc(N)c2cc(NC(=O)\C=C\c3ccccc3)ccc2n1
Show InChI InChI=1S/C19H17N3O/c1-13-11-17(20)16-12-15(8-9-18(16)21-13)22-19(23)10-7-14-5-3-2-4-6-14/h2-12H,1H3,(H2,20,21)(H,22,23)/b10-7+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.


J Med Chem 35: 252-8 (1992)


Article DOI: 10.1021/jm00080a008
More data for this
Ligand-Target Pair
Protein kinase C, PKC; classical


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229919
PNG
(CHEMBL101538)
Show SMILES CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@@H](N)CCSC
Show InChI InChI=1S/C24H47N3O2S/c1-3-4-5-6-7-8-9-10-11-12-16-23(28)27-18-14-13-15-21(27)20-26-24(29)22(25)17-19-30-2/h21-22H,3-20,25H2,1-2H3,(H,26,29)/t21?,22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.59E+5n/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
In vitro inhibition of [32P] incorporation into histones by rat brain partially purified Protein kinase C in the presence of PMA, [Ca2+] and phosphat...


J Med Chem 34: 2928-31 (1991)


Article DOI: 10.1021/jm00113a038
BindingDB Entry DOI: 10.7270/Q2KH0NZG
More data for this
Ligand-Target Pair
Protein kinase C, PKC; classical


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229918
PNG
(CHEMBL101731)
Show SMILES CCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@@H](N)CCCCN
Show InChI InChI=1S/C23H46N4O2/c1-2-3-4-5-6-7-8-9-16-22(28)27-18-13-11-14-20(27)19-26-23(29)21(25)15-10-12-17-24/h20-21H,2-19,24-25H2,1H3,(H,26,29)/t20?,21-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.99E+5n/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
In vitro inhibition of [32P] incorporation into histones by rat brain partially purified Protein kinase C in the presence of PMA, [Ca2+] and phosphat...


J Med Chem 34: 2928-31 (1991)


Article DOI: 10.1021/jm00113a038
BindingDB Entry DOI: 10.7270/Q2KH0NZG
More data for this
Ligand-Target Pair