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7 similar compounds to monomer 50229946

Compile data set for download or QSAR
Wt: 406.4
BDBM50229936
Wt: 505.4
BDBM50229940
Wt: 423.6
BDBM50229923
Wt: 367.5
BDBM50229924
Wt: 424.6
BDBM50229925
Wt: 447.6
BDBM50229927
Wt: 466.7
BDBM50229928

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50229936,50229940,50229923,50229924,50229925,50229927,50229928   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C, PKC; classical


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229923
PNG
(CHEMBL317827)
Show SMILES CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@@H](N)CC(C)C
Show InChI InChI=1S/C25H49N3O2/c1-4-5-6-7-8-9-10-11-12-13-17-24(29)28-18-15-14-16-22(28)20-27-25(30)23(26)19-21(2)3/h21-23H,4-20,26H2,1-3H3,(H,27,30)/t22?,23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.54E+5n/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Inhibition of PMA and [Ca2+] induced 32P incorporation into histones by partially purified rat brain Protein kinase C


J Med Chem 34: 2928-31 (1991)


Article DOI: 10.1021/jm00113a038
BindingDB Entry DOI: 10.7270/Q2KH0NZG
More data for this
Ligand-Target Pair
Protein kinase C, PKC; classical


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229928
PNG
(CHEMBL97998)
Show SMILES CCCCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@@H](N)CCCCN
Show InChI InChI=1S/C27H54N4O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-20-26(32)31-22-17-15-18-24(31)23-30-27(33)25(29)19-14-16-21-28/h24-25H,2-23,28-29H2,1H3,(H,30,33)/t24?,25-/m0/s1
PDB

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Inhibition of PMA and [Ca2+] induced 32P incorporation into histones by partially purified rat brain Protein kinase C


J Med Chem 34: 2928-31 (1991)


Article DOI: 10.1021/jm00113a038
BindingDB Entry DOI: 10.7270/Q2KH0NZG
More data for this
Ligand-Target Pair
Protein kinase C, PKC; classical


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229925
PNG
(CHEMBL433408)
Show SMILES CCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@@H](N)CCCCN
Show InChI InChI=1S/C24H48N4O2/c1-2-3-4-5-6-7-8-9-10-17-23(29)28-19-14-12-15-21(28)20-27-24(30)22(26)16-11-13-18-25/h21-22H,2-20,25-26H2,1H3,(H,27,30)/t21?,22-/m0/s1
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.02E+5n/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
In vitro inhibition of [32P] incorporation into histones by rat brain partially purified Protein kinase C in the presence of PMA, [Ca2+] and phosphat...


J Med Chem 34: 2928-31 (1991)


Article DOI: 10.1021/jm00113a038
BindingDB Entry DOI: 10.7270/Q2KH0NZG
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229936
PNG
(CHEMBL1788279)
Show SMILES COc1ccc(cc1)C(=O)c1c(C)n2[C@@H](CN3CCOCC3)COc3cccc1c23
Show InChI InChI=1/C24H26N2O4/c1-16-22(24(27)17-6-8-19(28-2)9-7-17)20-4-3-5-21-23(20)26(16)18(15-30-21)14-25-10-12-29-13-11-25/h3-9,18H,10-15H2,1-2H3/t18-/s2
PDB
MMDB

NCI pathway
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KEGG

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PC cid
PC sid
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PubMed
n/an/a 1.75E+4n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to displace 50% of 0.5 nM [3H](aminoalkyl)indole binding to cannabinoid receptor in rat cerebellum membranes


J Med Chem 35: 124-35 (1992)


Article DOI: 10.1021/jm00079a016
BindingDB Entry DOI: 10.7270/Q2SF2ZDZ
More data for this
Ligand-Target Pair
Protein kinase C, PKC; classical


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229927
PNG
(CHEMBL319666)
Show SMILES CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@@H](N)Cc1ncc[nH]1
Show InChI InChI=1S/C25H45N5O2/c1-2-3-4-5-6-7-8-9-10-11-15-24(31)30-18-13-12-14-21(30)20-29-25(32)22(26)19-23-27-16-17-28-23/h16-17,21-22H,2-15,18-20,26H2,1H3,(H,27,28)(H,29,32)/t21?,22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
In vitro inhibition of [32P] incorporation into histones by rat brain partially purified Protein kinase C in the presence of PMA, [Ca2+] and phosphat...


J Med Chem 34: 2928-31 (1991)


Article DOI: 10.1021/jm00113a038
BindingDB Entry DOI: 10.7270/Q2KH0NZG
More data for this
Ligand-Target Pair
Cannabinoid receptor


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229940
PNG
(CHEMBL286248)
Show SMILES Cc1c(C(=O)c2ccc(Br)c3ccccc23)c2cccc3OCC(CN4CCOCC4)n1c23
Show InChI InChI=1/C27H25BrN2O3/c1-17-25(27(31)21-9-10-23(28)20-6-3-2-5-19(20)21)22-7-4-8-24-26(22)30(17)18(16-33-24)15-29-11-13-32-14-12-29/h2-10,18H,11-16H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to displace 50% of 0.5 nM [3H](aminoalkyl)indole binding to cannabinoid receptor in rat cerebellum membranes


J Med Chem 35: 124-35 (1992)


Article DOI: 10.1021/jm00079a016
BindingDB Entry DOI: 10.7270/Q2SF2ZDZ
More data for this
Ligand-Target Pair
Protein kinase C, PKC; classical


(Rattus norvegicus (Rat)-Rattus norvegicus (rat))
BDBM50229924
PNG
(CHEMBL99156)
Show SMILES CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)CN
Show InChI InChI=1/C21H41N3O2/c1-2-3-4-5-6-7-8-9-10-11-15-21(26)24-16-13-12-14-19(24)18-23-20(25)17-22/h19H,2-18,22H2,1H3,(H,23,25)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
In vitro inhibition of [32P] incorporation into histones by rat brain partially purified Protein kinase C in the presence of PMA, [Ca2+] and phosphat...


J Med Chem 34: 2928-31 (1991)


Article DOI: 10.1021/jm00113a038
BindingDB Entry DOI: 10.7270/Q2KH0NZG
More data for this
Ligand-Target Pair