BindingDB logo
myBDB logout

1 similar compounds to monomer 50001775

Compile data set for download or QSAR
Wt: 324.3
BDBM50230006

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230006   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(RAT)
BDBM50230006
PNG
(CHEMBL99266)
Show SMILES CN(C(C#CCN1CCCC1)c1ccccc1)C(=O)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-21(16(23)17(18,19)20)15(14-8-3-2-4-9-14)10-7-13-22-11-5-6-12-22/h2-4,8-9,15H,5-6,11-13H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
230n/an/an/an/an/an/an/an/a



University of Uppsala

Curated by ChEMBL


Assay Description
Inhibition of [3H]N-methylscopolamine binding to muscarinic acetylcholine receptor of rat cerebral cortex.


J Med Chem 35: 285-94 (1992)


Article DOI: 10.1021/jm00080a013
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50230006
PNG
(CHEMBL99266)
Show SMILES CN(C(C#CCN1CCCC1)c1ccccc1)C(=O)C(F)(F)F
Show InChI InChI=1S/C17H19F3N2O/c1-21(16(23)17(18,19)20)15(14-8-3-2-4-9-14)10-7-13-22-11-5-6-12-22/h2-4,8-9,15H,5-6,11-13H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/a 500n/an/an/an/an/a



University of Uppsala

Curated by ChEMBL


Assay Description
Determination of dissociation constant from antimuscarinic activity on isolated guinea pig ileum.


J Med Chem 35: 285-94 (1992)


Article DOI: 10.1021/jm00080a013
More data for this
Ligand-Target Pair