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3 similar compounds to monomer 50230280

Compile data set for download or QSAR
Wt: 188.2
BDBM50230281
Wt: 256.3
BDBM50230282
Wt: 304.3
BDBM50230283

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50230281,50230282,50230283   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 3


(Homo sapiens (Human))
BDBM50230281
PNG
(CHEMBL144682)
Show SMILES CCCc1nccc2nc(O)ccc12
Show InChI InChI=1S/C11H12N2O/c1-2-3-9-8-4-5-11(14)13-10(8)6-7-12-9/h4-7H,2-3H2,1H3,(H,13,14)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 48n/an/an/an/an/an/a



Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against cAMP PDE III.


J Med Chem 35: 4858-65 (1992)


Article DOI: 10.1021/jm00104a012
BindingDB Entry DOI: 10.7270/Q2H13480
More data for this
Ligand-Target Pair
Phosphodiesterase 4


(Homo sapiens (Human))
BDBM50230283
PNG
(CHEMBL95669)
Show SMILES CCCn1cnc2c1c(=O)n(-c1ccccc1)c1ncccc21
Show InChI InChI=1S/C18H16N4O/c1-2-11-21-12-20-15-14-9-6-10-19-17(14)22(18(23)16(15)21)13-7-4-3-5-8-13/h3-10,12H,2,11H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 520n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Canine Tracheal Smooth Muscle PDE 4


J Med Chem 35: 4866-74 (1992)


Article DOI: 10.1021/jm00104a013
BindingDB Entry DOI: 10.7270/Q2C82CJ8
More data for this
Ligand-Target Pair
Phosphodiesterase 4


(Homo sapiens (Human))
BDBM50230282
PNG
(CHEMBL143079)
Show SMILES CCCCn1c2ncccc2c2ncn(C)c2c1=O
Show InChI InChI=1S/C14H16N4O/c1-3-4-8-18-13-10(6-5-7-15-13)11-12(14(18)19)17(2)9-16-11/h5-7,9H,3-4,8H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Canine Tracheal Smooth Muscle PDE 4


J Med Chem 35: 4866-74 (1992)


Article DOI: 10.1021/jm00104a013
BindingDB Entry DOI: 10.7270/Q2C82CJ8
More data for this
Ligand-Target Pair