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6 similar compounds to monomer 50230429

Compile data set for download or QSAR
Wt: 328.3
BDBM50230433
Wt: 326.3
BDBM50230435
Wt: 387.2
BDBM50230427
Wt: 336.4
BDBM50230428
Wt: 320.7
BDBM50230430
Wt: 308.3
BDBM50230431

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50230433,50230435,50230427,50230428,50230430,50230431   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50230427
PNG
(CHEMBL171490)
Show SMILES CCCCc1nc2ccccc2n1Cc1ccc(cc1Br)C(O)=O
Show InChI InChI=1S/C19H19BrN2O2/c1-2-3-8-18-21-16-6-4-5-7-17(16)22(18)12-14-10-9-13(19(23)24)11-15(14)20/h4-7,9-11H,2-3,8,12H2,1H3,(H,23,24)
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n/an/a 3.70E+3n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.


J Med Chem 35: 877-85 (1992)


Article DOI: 10.1021/jm00083a011
BindingDB Entry DOI: 10.7270/Q23R0W37
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50230428
PNG
(CHEMBL352376)
Show SMILES CCCCCCc1nc2ccccc2n1Cc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H24N2O2/c1-2-3-4-5-10-20-22-18-8-6-7-9-19(18)23(20)15-16-11-13-17(14-12-16)21(24)25/h6-9,11-14H,2-5,10,15H2,1H3,(H,24,25)
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n/an/a 640n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.


J Med Chem 35: 877-85 (1992)


Article DOI: 10.1021/jm00083a011
BindingDB Entry DOI: 10.7270/Q23R0W37
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50230435
PNG
(CHEMBL172577)
Show SMILES CCCCc1nc2cc(F)ccc2n1Cc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C19H19FN2O2/c1-2-3-4-18-21-16-11-15(20)9-10-17(16)22(18)12-13-5-7-14(8-6-13)19(23)24/h5-11H,2-4,12H2,1H3,(H,23,24)
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n/an/a 4.90E+3n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.


J Med Chem 35: 877-85 (1992)


Article DOI: 10.1021/jm00083a011
BindingDB Entry DOI: 10.7270/Q23R0W37
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50230431
PNG
(CHEMBL171456)
Show SMILES CCCCc1nc2ccccc2n1Cc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C19H20N2O2/c1-2-3-8-18-20-16-6-4-5-7-17(16)21(18)13-14-9-11-15(12-10-14)19(22)23/h4-7,9-12H,2-3,8,13H2,1H3,(H,22,23)
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n/an/a 1.80E+3n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.


J Med Chem 35: 877-85 (1992)


Article DOI: 10.1021/jm00083a011
BindingDB Entry DOI: 10.7270/Q23R0W37
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50230433
PNG
(CHEMBL422562)
Show SMILES OC(=O)c1ccccc1-c1ccc(Cn2cnc3ccccc23)cc1
Show InChI InChI=1S/C21H16N2O2/c24-21(25)18-6-2-1-5-17(18)16-11-9-15(10-12-16)13-23-14-22-19-7-3-4-8-20(19)23/h1-12,14H,13H2,(H,24,25)
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n/an/a 1.40E+5n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.


J Med Chem 35: 877-85 (1992)


Article DOI: 10.1021/jm00083a011
BindingDB Entry DOI: 10.7270/Q23R0W37
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50230430
PNG
(CHEMBL354436)
Show SMILES CCCCc1nc(Cl)c2COc3cc(ccc3Cn12)C(O)=O
Show InChI InChI=1S/C16H17ClN2O3/c1-2-3-4-14-18-15(17)12-9-22-13-7-10(16(20)21)5-6-11(13)8-19(12)14/h5-7H,2-4,8-9H2,1H3,(H,20,21)
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n/an/a 1.50E+4n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands.


J Med Chem 35: 877-85 (1992)


Article DOI: 10.1021/jm00083a011
BindingDB Entry DOI: 10.7270/Q23R0W37
More data for this
Ligand-Target Pair