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38 similar compounds to monomer 50230677

Compile data set for download or QSAR
Wt: 614.7
BDBM50230678
Wt: 529.6
BDBM50230682
Wt: 620.7
BDBM50230679
Wt: 616.7
BDBM50230680
Wt: 626.7
BDBM50230683
Wt: 576.6
BDBM50230689
Wt: 600.7
BDBM50230686
Wt: 628.7
BDBM50230684
Wt: 543.6
BDBM50230674
Wt: 515.6
BDBM50230668
Wt: 298.3
BDBM50230634
Wt: 286.3
BDBM50230622
Wt: 290.3
BDBM50230623
Wt: 286.3
BDBM50230624
Wt: 300.3
BDBM50230625
Displayed 1 to 15 (of 38 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50230678,50230682,50230679,50230680,50230683,50230689,50230686,50230684,50230674,50230668,50230634,50230622,50230623,50230624,50230625   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin receptor


(MOUSE)
BDBM50230683
PNG
(CHEMBL3351024)
Show SMILES C[C@](Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)N[C@H](CNC(=O)\C=C\C(O)=O)Cc1ccccc1
Show InChI InChI=1S/C36H42N4O6/c1-36(19-27-20-37-30-10-6-5-9-29(27)30,40-35(45)46-33-25-14-23-13-24(16-25)17-26(33)15-23)34(44)39-28(18-22-7-3-2-4-8-22)21-38-31(41)11-12-32(42)43/h2-12,20,23-26,28,33,37H,13-19,21H2,1H3,(H,38,41)(H,39,44)(H,40,45)(H,42,43)/b12-11+/t23?,24?,25?,26?,28-,33?,36+/m0/s1
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0.708n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230678
PNG
(CHEMBL287735)
Show SMILES C[C@](Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NC[C@H](NC(=O)CCC(O)=O)c1ccccc1
Show InChI InChI=1S/C35H42N4O6/c1-35(18-26-19-36-28-10-6-5-9-27(26)28,39-34(44)45-32-24-14-21-13-22(16-24)17-25(32)15-21)33(43)37-20-29(23-7-3-2-4-8-23)38-30(40)11-12-31(41)42/h2-10,19,21-22,24-25,29,32,36H,11-18,20H2,1H3,(H,37,43)(H,38,40)(H,39,44)(H,41,42)/t21?,22?,24?,25?,29-,32?,35+/m0/s1
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1.40n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230680
PNG
(CHEMBL3350364)
Show SMILES C[C@](Cc1c[nH]c2ccccc12)(NC(=O)O[C@H]1C[C@@H]2CC[C@]1(C)C2(C)C)C(=O)NC[C@H](NC(=O)CCC(O)=O)c1ccccc1
Show InChI InChI=1S/C35H44N4O6/c1-33(2)24-16-17-34(33,3)28(18-24)45-32(44)39-35(4,19-23-20-36-26-13-9-8-12-25(23)26)31(43)37-21-27(22-10-6-5-7-11-22)38-29(40)14-15-30(41)42/h5-13,20,24,27-28,36H,14-19,21H2,1-4H3,(H,37,43)(H,38,40)(H,39,44)(H,41,42)/t24-,27-,28-,34-,35+/m0/s1
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2n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230689
PNG
(CHEMBL3351018)
Show SMILES C[C@@H]1CCCC[C@H]1OC(=O)N[C@](C)(Cc1c[nH]c2ccccc12)C(=O)NC[C@H](NC(=O)CCC(O)=O)c1ccccc1
Show InChI InChI=1S/C32H40N4O6/c1-21-10-6-9-15-27(21)42-31(41)36-32(2,18-23-19-33-25-14-8-7-13-24(23)25)30(40)34-20-26(22-11-4-3-5-12-22)35-28(37)16-17-29(38)39/h3-5,7-8,11-14,19,21,26-27,33H,6,9-10,15-18,20H2,1-2H3,(H,34,40)(H,35,37)(H,36,41)(H,38,39)/t21-,26+,27-,32-/m1/s1
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3.70n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230684
PNG
(CHEMBL353157 | PD-135118)
Show SMILES C[C@](Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)N[C@H](CNC(=O)CCC(O)=O)Cc1ccccc1
Show InChI InChI=1S/C36H44N4O6/c1-36(19-27-20-37-30-10-6-5-9-29(27)30,40-35(45)46-33-25-14-23-13-24(16-25)17-26(33)15-23)34(44)39-28(18-22-7-3-2-4-8-22)21-38-31(41)11-12-32(42)43/h2-10,20,23-26,28,33,37H,11-19,21H2,1H3,(H,38,41)(H,39,44)(H,40,45)(H,42,43)/t23?,24?,25?,26?,28-,33?,36+/m0/s1
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4n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230682
PNG
(CHEMBL3351017)
Show SMILES C[C@](Cc1c[nH]c2ccccc12)(NC(=O)OC12CC3CC(CC(C3)C1)C2)C(=O)N[C@H](CO)Cc1ccccc1
Show InChI InChI=1S/C32H39N3O4/c1-31(18-25-19-33-28-10-6-5-9-27(25)28,29(37)34-26(20-36)14-21-7-3-2-4-8-21)35-30(38)39-32-15-22-11-23(16-32)13-24(12-22)17-32/h2-10,19,22-24,26,33,36H,11-18,20H2,1H3,(H,34,37)(H,35,38)/t22?,23?,24?,26-,31+,32?/m0/s1
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20n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230674
PNG
(CHEMBL3351014)
Show SMILES OC(=O)C[C@@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC1C2CC3CC(C2)CC1C3
Show InChI InChI=1S/C32H37N3O5/c36-29(37)17-25(15-19-6-2-1-3-7-19)34-31(38)28(16-24-18-33-27-9-5-4-8-26(24)27)35-32(39)40-30-22-11-20-10-21(13-22)14-23(30)12-20/h1-9,18,20-23,25,28,30,33H,10-17H2,(H,34,38)(H,35,39)(H,36,37)/t20?,21?,22?,23?,25-,28-,30?/m1/s1
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138n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230686
PNG
(CHEMBL2021373)
Show SMILES OC(=O)CCC(=O)NC(CNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC1C2CC3CC(C2)CC1C3)c1ccccc1
Show InChI InChI=1/C34H40N4O6/c39-30(10-11-31(40)41)37-29(22-6-2-1-3-7-22)19-36-33(42)28(17-25-18-35-27-9-5-4-8-26(25)27)38-34(43)44-32-23-13-20-12-21(15-23)16-24(32)14-20/h1-9,18,20-21,23-24,28-29,32,35H,10-17,19H2,(H,36,42)(H,37,39)(H,38,43)(H,40,41)/t20?,21?,23?,24?,28-,29?,32?/s2
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355n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230679
PNG
(CHEMBL3350691)
Show SMILES O.CC1(C)C2CCC1(C)[C@H](C2)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC[C@H](NC(=O)CCC(O)=O)c1ccccc1
Show InChI InChI=1S/C34H42N4O6.H2O/c1-33(2)23-15-16-34(33,3)28(18-23)44-32(43)38-26(17-22-19-35-25-12-8-7-11-24(22)25)31(42)36-20-27(21-9-5-4-6-10-21)37-29(39)13-14-30(40)41;/h4-12,19,23,26-28,35H,13-18,20H2,1-3H3,(H,36,42)(H,37,39)(H,38,43)(H,40,41);1H2/t23?,26-,27-,28-,34?;/m0./s1
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398n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230668
PNG
(CHEMBL3350393)
Show SMILES OC[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC1C2CC3CC(C2)CC1C3
Show InChI InChI=1S/C31H37N3O4/c35-18-25(15-19-6-2-1-3-7-19)33-30(36)28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-11-20-10-21(13-22)14-23(29)12-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20?,21?,22?,23?,25-,28+,29?/m0/s1
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813n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50230668
PNG
(CHEMBL3350393)
Show SMILES OC[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC1C2CC3CC(C2)CC1C3
Show InChI InChI=1S/C31H37N3O4/c35-18-25(15-19-6-2-1-3-7-19)33-30(36)28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-11-20-10-21(13-22)14-23(29)12-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20?,21?,22?,23?,25-,28+,29?/m0/s1
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2.09E+3n/an/an/an/an/an/an/an/a



Parke-Davis Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouse


J Med Chem 35: 1572-7 (1992)


Article DOI: 10.1021/jm00087a011
BindingDB Entry DOI: 10.7270/Q26H4KM8
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50230622
PNG
(CHEMBL274212)
Show SMILES CCOc1cc2OCOc2cc1Cc1ccc(OC)cc1
Show InChI InChI=1S/C17H18O4/c1-3-19-15-10-17-16(20-11-21-17)9-13(15)8-12-4-6-14(18-2)7-5-12/h4-7,9-10H,3,8,11H2,1-2H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)


J Med Chem 35: 1058-67 (1992)


Article DOI: 10.1021/jm00084a011
BindingDB Entry DOI: 10.7270/Q2KS6TSB
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50230625
PNG
(CHEMBL10686)
Show SMILES COc1ccc(CCCc2cc3OCOc3cc2OC)cc1
Show InChI InChI=1S/C18H20O4/c1-19-15-8-6-13(7-9-15)4-3-5-14-10-17-18(22-12-21-17)11-16(14)20-2/h6-11H,3-5,12H2,1-2H3
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n/an/a 3.80E+3n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)


J Med Chem 35: 1058-67 (1992)


Article DOI: 10.1021/jm00084a011
BindingDB Entry DOI: 10.7270/Q2KS6TSB
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50230624
PNG
(CHEMBL269215)
Show SMILES COc1ccc(CCc2cc3OCOc3cc2OC)cc1
Show InChI InChI=1S/C17H18O4/c1-18-14-7-4-12(5-8-14)3-6-13-9-16-17(21-11-20-16)10-15(13)19-2/h4-5,7-10H,3,6,11H2,1-2H3
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n/an/a 8.80E+3n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)


J Med Chem 35: 1058-67 (1992)


Article DOI: 10.1021/jm00084a011
BindingDB Entry DOI: 10.7270/Q2KS6TSB
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50230634
PNG
(CHEMBL10653)
Show SMILES CCOc1cc2OCOc2cc1\C=C/c1ccc(OC)cc1
Show InChI InChI=1S/C18H18O4/c1-3-20-16-11-18-17(21-12-22-18)10-14(16)7-4-13-5-8-15(19-2)9-6-13/h4-11H,3,12H2,1-2H3/b7-4-
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n/an/a>4.00E+4n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)


J Med Chem 35: 1058-67 (1992)


Article DOI: 10.1021/jm00084a011
BindingDB Entry DOI: 10.7270/Q2KS6TSB
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50230623
PNG
(CHEMBL10255)
Show SMILES COc1ccc(cc1O)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C16H18O5/c1-18-13-6-5-10(7-12(13)17)11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3
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n/an/a>4.00E+4n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)


J Med Chem 35: 1058-67 (1992)


Article DOI: 10.1021/jm00084a011
BindingDB Entry DOI: 10.7270/Q2KS6TSB
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50230623
PNG
(CHEMBL10255)
Show SMILES COc1ccc(cc1O)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C16H18O5/c1-18-13-6-5-10(7-12(13)17)11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3
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n/an/a>4.00E+4n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)


J Med Chem 35: 1058-67 (1992)


Article DOI: 10.1021/jm00084a011
BindingDB Entry DOI: 10.7270/Q2KS6TSB
More data for this
Ligand-Target Pair