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9 similar compounds to monomer 50233833

Compile data set for download or QSAR
Wt: 408.1
BDBM50233825
Wt: 453.2
BDBM50233827
Wt: 487.5
BDBM50233818
Wt: 459.4
BDBM50233820
Wt: 519.6
BDBM50233838
Wt: 408.1
BDBM50233824
Wt: 453.2
BDBM50233828
Wt: 408.1
BDBM50233826
Wt: 473.4
BDBM50233817

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50233825,50233827,50233818,50233820,50233838,50233824,50233828,50233826,50233817   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Xanthine dehydrogenase/oxidase


(Homo sapiens (Human))
BDBM50233817
PNG
(CHEMBL4095851)
Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccc(O)c2oc(cc12)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C27H23NO7/c1-34-27(33)20(13-16-5-3-2-4-6-16)28-25(32)12-9-17-7-11-22(30)26-19(17)15-24(35-26)18-8-10-21(29)23(31)14-18/h2-12,14-15,20,29-31H,13H2,1H3,(H,28,32)/b12-9+/t20-/m0/s1
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Article
PubMed
n/an/a 1.49E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...


Eur J Med Chem 124: 637-648 (2016)


Article DOI: 10.1016/j.ejmech.2016.08.019
More data for this
Ligand-Target Pair
Xanthine dehydrogenase/oxidase


(Homo sapiens (Human))
BDBM50233818
PNG
(CHEMBL4092465)
Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccc(OC)c2oc(cc12)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C28H25NO7/c1-34-24-12-9-18(20-16-25(36-27(20)24)19-8-11-22(30)23(31)15-19)10-13-26(32)29-21(28(33)35-2)14-17-6-4-3-5-7-17/h3-13,15-16,21,30-31H,14H2,1-2H3,(H,29,32)/b13-10+/t21-/m0/s1
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Article
PubMed
n/an/a>6.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...


Eur J Med Chem 124: 637-648 (2016)


Article DOI: 10.1016/j.ejmech.2016.08.019
More data for this
Ligand-Target Pair
Xanthine dehydrogenase/oxidase


(Homo sapiens (Human))
BDBM50233820
PNG
(CHEMBL4104607)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccc(O)c2oc(cc12)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C26H21NO7/c28-20-9-7-17(13-22(20)30)23-14-18-16(6-10-21(29)25(18)34-23)8-11-24(31)27-19(26(32)33)12-15-4-2-1-3-5-15/h1-11,13-14,19,28-30H,12H2,(H,27,31)(H,32,33)/b11-8+/t19-/m0/s1
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Article
PubMed
n/an/a 6.04E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...


Eur J Med Chem 124: 637-648 (2016)


Article DOI: 10.1016/j.ejmech.2016.08.019
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50233824
PNG
(CHEMBL4070673)
Show SMILES Oc1ccc2c(oc(cc2=O)-c2cc(O)c(O)c([123I])c2)c1O
Show InChI InChI=1S/C15H9IO6/c16-8-3-6(4-11(19)13(8)20)12-5-10(18)7-1-2-9(17)14(21)15(7)22-12/h1-5,17,19-21H/i16-4
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Article
PubMed
n/an/a 1.73E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...


Eur J Med Chem 125: 117-129 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.028
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Homo sapiens (Human))
BDBM50233838
PNG
(CHEMBL1800992)
Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)CCCCC)c3cc(ccc23)C(O)=O)cc1
Show InChI InChI=1S/C32H41NO5/c1-3-5-7-8-9-11-12-24-14-17-27(18-15-24)38-23-26(34)21-33-22-29(31(35)13-10-6-4-2)28-20-25(32(36)37)16-19-30(28)33/h14-20,22H,3-13,21,23H2,1-2H3,(H,36,37)
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Article
PubMed
n/an/a 71n/an/an/an/an/an/a



University of M£nster

Curated by ChEMBL


Assay Description
Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...


Eur J Med Chem 125: 1107-1114 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.039
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50233826
PNG
(CHEMBL4090090)
Show SMILES Oc1ccc(cc1O)-c1cc(=O)c2cc([123I])c(O)c(O)c2o1
Show InChI InChI=1S/C15H9IO6/c16-8-4-7-10(18)5-12(22-15(7)14(21)13(8)20)6-1-2-9(17)11(19)3-6/h1-5,17,19-21H/i16-4
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PubMed
n/an/a 1.65E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...


Eur J Med Chem 125: 117-129 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.028
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50233827
PNG
(CHEMBL4076246)
Show SMILES C\C(=C/C(=O)Nc1cc([123I])ccc1C(O)=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H16INO3/c1-13(15-7-6-14-4-2-3-5-16(14)11-15)10-20(24)23-19-12-17(22)8-9-18(19)21(25)26/h2-12H,1H3,(H,23,24)(H,25,26)/b13-10+/i22-4
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PubMed
n/an/a 2.81E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...


Eur J Med Chem 125: 117-129 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.028
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50233828
PNG
(CHEMBL4062047)
Show SMILES C\C(=C/C(=O)Nc1ccc([123I])cc1C(O)=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H16INO3/c1-13(15-7-6-14-4-2-3-5-16(14)11-15)10-20(24)23-19-9-8-17(22)12-18(19)21(25)26/h2-12H,1H3,(H,23,24)(H,25,26)/b13-10+/i22-4
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Article
PubMed
n/an/a 3.01E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...


Eur J Med Chem 125: 117-129 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.028
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50233825
PNG
(CHEMBL4081286)
Show SMILES Oc1cc([123I])c(cc1O)-c1cc(=O)c2ccc(O)c(O)c2o1
Show InChI InChI=1S/C15H9IO6/c16-8-4-12(20)11(19)3-7(8)13-5-10(18)6-1-2-9(17)14(21)15(6)22-13/h1-5,17,19-21H/i16-4
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Article
PubMed
n/an/a 969n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...


Eur J Med Chem 125: 117-129 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.028
More data for this
Ligand-Target Pair