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2 similar compounds to monomer 50233830

Compile data set for download or QSAR
Wt: 408.1
BDBM50233824
Wt: 505.4
BDBM50233821

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233824,50233821   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50233824
PNG
(CHEMBL4070673)
Show SMILES Oc1ccc2c(oc(cc2=O)-c2cc(O)c(O)c([123I])c2)c1O
Show InChI InChI=1S/C15H9IO6/c16-8-3-6(4-11(19)13(8)20)12-5-10(18)7-1-2-9(17)14(21)15(7)22-12/h1-5,17,19-21H/i16-4
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
MMDB
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.73E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...


Eur J Med Chem 125: 117-129 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.028
More data for this
Ligand-Target Pair
Xanthine dehydrogenase/oxidase


(Homo sapiens (Human))
BDBM50233821
PNG
(CHEMBL4083271)
Show SMILES COc1ccc(\C=C\C(=O)N[C@@H](Cc2ccc(O)c(O)c2)C(O)=O)c2cc(oc12)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C27H23NO9/c1-36-23-8-4-15(17-13-24(37-26(17)23)16-3-7-20(30)22(32)12-16)5-9-25(33)28-18(27(34)35)10-14-2-6-19(29)21(31)11-14/h2-9,11-13,18,29-32H,10H2,1H3,(H,28,33)(H,34,35)/b9-5+/t18-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>6.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...


Eur J Med Chem 124: 637-648 (2016)


Article DOI: 10.1016/j.ejmech.2016.08.019
More data for this
Ligand-Target Pair