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1 similar compounds to monomer 31068

Compile data set for download or QSAR
Wt: 302.2
BDBM50235328

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235328   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM50235328
PNG
(CHEMBL4089667)
Show SMILES OC(=O)[C@@H]1CCC=C(C[C@]11Oc2ccc(O)cc2C1=O)C=O
Show InChI InChI=1/C16H14O6/c17-8-9-2-1-3-12(15(20)21)16(7-9)14(19)11-6-10(18)4-5-13(11)22-16/h2,4-6,8,12,18H,1,3,7H2,(H,20,21)/t12-,16-/s2
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Article
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged JAK3 cytoplasmic domain (781 to 1124 residues) expressed in baculovirus expression system incubated for 1 ...


J Nat Prod 80: 61-70 (2017)


Article DOI: 10.1021/acs.jnatprod.6b00431
BindingDB Entry DOI: 10.7270/Q2CV4M0M
More data for this
Ligand-Target Pair