BindingDB logo
myBDB logout

16 similar compounds to monomer 50257580

Compile data set for download or QSAR
Wt: 296.3
BDBM50257574
Wt: 314.3
BDBM50257575
Wt: 365.2
BDBM50257577
Wt: 365.2
BDBM50257578
Wt: 348.7
BDBM50257579
Wt: 363.7
BDBM50257582
Wt: 364.7
BDBM50257584
Wt: 363.7
BDBM50257585
Wt: 348.7
BDBM50257532
Wt: 314.3
BDBM50257533
Wt: 349.7
BDBM50257535
Wt: 330.7
BDBM50257628
Wt: 321.3
BDBM50257630
Wt: 330.7
BDBM50257631
Wt: 332.3
BDBM50257632
Displayed 1 to 15 (of 16 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50257574,50257575,50257577,50257578,50257579,50257582,50257584,50257585,50257532,50257533,50257535,50257628,50257630,50257631,50257632   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257582
PNG
(2-(2-aminopyridin-4-yl)-3-(3-chloro-4-fluorophenyl...)
Show SMILES Nc1cc(ccn1)-c1[nH]c2ccc(nc2c1-c1ccc(F)c(Cl)c1)C#N
Show InChI InChI=1S/C19H11ClFN5/c20-13-7-10(1-3-14(13)21)17-18(11-5-6-24-16(23)8-11)26-15-4-2-12(9-22)25-19(15)17/h1-8,26H,(H2,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257582
PNG
(2-(2-aminopyridin-4-yl)-3-(3-chloro-4-fluorophenyl...)
Show SMILES Nc1cc(ccn1)-c1[nH]c2ccc(nc2c1-c1ccc(F)c(Cl)c1)C#N
Show InChI InChI=1S/C19H11ClFN5/c20-13-7-10(1-3-14(13)21)17-18(11-5-6-24-16(23)8-11)26-15-4-2-12(9-22)25-19(15)17/h1-8,26H,(H2,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257579
PNG
(3-(3-chloro-5-fluorophenyl)-2-(pyridin-4-yl)-1H-py...)
Show SMILES Fc1cc(Cl)cc(c1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H10ClFN4/c20-13-7-12(8-14(21)9-13)17-18(11-3-5-23-6-4-11)25-16-2-1-15(10-22)24-19(16)17/h1-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 340n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257632
PNG
(3-(3,4-difluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo...)
Show SMILES Fc1ccc(cc1F)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H10F2N4/c20-14-3-1-12(9-15(14)21)17-18(11-5-7-23-8-6-11)25-16-4-2-13(10-22)24-19(16)17/h1-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.59E+3n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257575
PNG
(3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Show SMILES Fc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H11FN4/c20-14-3-1-12(2-4-14)17-18(13-7-9-22-10-8-13)24-16-6-5-15(11-21)23-19(16)17/h1-10,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.95E+3n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257574
PNG
(3-phenyl-2-(pyridin-4-yl)-1H-pyrrolo[3,2-b]pyridin...)
Show SMILES N#Cc1ccc2[nH]c(c(-c3ccccc3)c2n1)-c1ccncc1
Show InChI InChI=1S/C19H12N4/c20-12-15-6-7-16-19(22-15)17(13-4-2-1-3-5-13)18(23-16)14-8-10-21-11-9-14/h1-11,23H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.09E+3n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257578
PNG
(3-(3,5-dichlorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo...)
Show SMILES Clc1cc(Cl)cc(c1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H10Cl2N4/c20-13-7-12(8-14(21)9-13)17-18(11-3-5-23-6-4-11)25-16-2-1-15(10-22)24-19(16)17/h1-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.55E+3n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257628
PNG
(3-(4-chlorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Show SMILES Clc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H11ClN4/c20-14-3-1-12(2-4-14)17-18(13-7-9-22-10-8-13)24-16-6-5-15(11-21)23-19(16)17/h1-10,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257577
PNG
(3-(3,4-dichlorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo...)
Show SMILES Clc1ccc(cc1Cl)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H10Cl2N4/c20-14-3-1-12(9-15(14)21)17-18(11-5-7-23-8-6-11)25-16-4-2-13(10-22)24-19(16)17/h1-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257532
PNG
(2-(2-chloropyridin-4-yl)-3-(4-fluorophenyl)-1H-pyr...)
Show SMILES Fc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1ccnc(Cl)c1
Show InChI InChI=1S/C19H10ClFN4/c20-16-9-12(7-8-23-16)18-17(11-1-3-13(21)4-2-11)19-15(25-18)6-5-14(10-22)24-19/h1-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257533
PNG
(3-(4-fluorophenyl)-2-(pyridin-3-yl)-1H-pyrrolo[3,2...)
Show SMILES Fc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1cccnc1
Show InChI InChI=1S/C19H11FN4/c20-14-5-3-12(4-6-14)17-18(13-2-1-9-22-11-13)24-16-8-7-15(10-21)23-19(16)17/h1-9,11,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257535
PNG
(3-(3-chloro-4-fluorophenyl)-2-(pyrimidin-5-yl)-1H-...)
Show SMILES Fc1ccc(cc1Cl)-c1c([nH]c2ccc(nc12)C#N)-c1cncnc1
Show InChI InChI=1S/C18H9ClFN5/c19-13-5-10(1-3-14(13)20)16-17(11-7-22-9-23-8-11)25-15-4-2-12(6-21)24-18(15)16/h1-5,7-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257584
PNG
(2-(2-aminopyrimidin-5-yl)-3-(3-chloro-4-fluorophen...)
Show SMILES Nc1ncc(cn1)-c1[nH]c2ccc(nc2c1-c1ccc(F)c(Cl)c1)C#N
Show InChI InChI=1S/C18H10ClFN6/c19-12-5-9(1-3-13(12)20)15-16(10-7-23-18(22)24-8-10)26-14-4-2-11(6-21)25-17(14)15/h1-5,7-8,26H,(H2,22,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257585
PNG
(2-(6-aminopyridin-3-yl)-3-(3-chloro-4-fluorophenyl...)
Show SMILES Nc1ccc(cn1)-c1[nH]c2ccc(nc2c1-c1ccc(F)c(Cl)c1)C#N
Show InChI InChI=1S/C19H11ClFN5/c20-13-7-10(1-4-14(13)21)17-18(11-2-6-16(23)24-9-11)26-15-5-3-12(8-22)25-19(15)17/h1-7,9,26H,(H2,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257630
PNG
(3-(4-cyanophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2-...)
Show SMILES N#Cc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C20H11N5/c21-11-13-1-3-14(4-2-13)18-19(15-7-9-23-10-8-15)25-17-6-5-16(12-22)24-20(17)18/h1-10,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257575
PNG
(3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Show SMILES Fc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H11FN4/c20-14-3-1-12(2-4-14)17-18(13-7-9-22-10-8-13)24-16-6-5-15(11-21)23-19(16)17/h1-10,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.95E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257631
PNG
(3-(3-chlorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Show SMILES Clc1cccc(c1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H11ClN4/c20-14-3-1-2-13(10-14)17-18(12-6-8-22-9-7-12)24-16-5-4-15(11-21)23-19(16)17/h1-10,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257574
PNG
(3-phenyl-2-(pyridin-4-yl)-1H-pyrrolo[3,2-b]pyridin...)
Show SMILES N#Cc1ccc2[nH]c(c(-c3ccccc3)c2n1)-c1ccncc1
Show InChI InChI=1S/C19H12N4/c20-12-15-6-7-16-19(22-15)17(13-4-2-1-3-5-13)18(23-16)14-8-10-21-11-9-14/h1-11,23H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.09E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257628
PNG
(3-(4-chlorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Show SMILES Clc1ccc(cc1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H11ClN4/c20-14-3-1-12(2-4-14)17-18(13-7-9-22-10-8-13)24-16-6-5-15(11-21)23-19(16)17/h1-10,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257578
PNG
(3-(3,5-dichlorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo...)
Show SMILES Clc1cc(Cl)cc(c1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H10Cl2N4/c20-13-7-12(8-14(21)9-13)17-18(11-3-5-23-6-4-11)25-16-2-1-15(10-22)24-19(16)17/h1-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.55E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257579
PNG
(3-(3-chloro-5-fluorophenyl)-2-(pyridin-4-yl)-1H-py...)
Show SMILES Fc1cc(Cl)cc(c1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H10ClFN4/c20-13-7-12(8-14(21)9-13)17-18(11-3-5-23-6-4-11)25-16-2-1-15(10-22)24-19(16)17/h1-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 340n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257632
PNG
(3-(3,4-difluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo...)
Show SMILES Fc1ccc(cc1F)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H10F2N4/c20-14-3-1-12(9-15(14)21)17-18(11-5-7-23-8-6-11)25-16-4-2-13(10-22)24-19(16)17/h1-9,25H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.59E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50257631
PNG
(3-(3-chlorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Show SMILES Clc1cccc(c1)-c1c([nH]c2ccc(nc12)C#N)-c1ccncc1
Show InChI InChI=1S/C19H11ClN4/c20-14-3-1-2-13(10-14)17-18(12-6-8-22-9-7-12)24-16-5-4-15(11-21)23-19(16)17/h1-10,24H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Technical University of Darmstadt

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human c-Met expressed in SF9 cells


Bioorg Med Chem Lett 19: 1879-82 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.069
BindingDB Entry DOI: 10.7270/Q2BK1C66
More data for this
Ligand-Target Pair