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3 similar compounds to monomer 50273595

Compile data set for download or QSAR
Wt: 278.3
BDBM50273528
Wt: 278.3
BDBM50273620
Wt: 250.3
BDBM50273594

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50273528,50273620,50273594   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Bos taurus)
BDBM50273528
PNG
(CHEMBL460608 | N-Methyl,N-(2-phenylethyl)-1H-indol...)
Show SMILES CN(CCc1ccccc1)C(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C18H18N2O/c1-20(12-11-14-7-3-2-4-8-14)18(21)17-13-15-9-5-6-10-16(15)19-17/h2-10,13,19H,11-12H2,1H3
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4n/an/an/an/an/an/an/an/a



Sapienza Università di Roma

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Monoamine oxidase


(Bos taurus)
BDBM50273620
PNG
(CHEMBL460828 | N-(1-Methyl-1H-indol-2-ylmethyl)-N-...)
Show SMILES CN(CCc1ccccc1)Cc1cc2ccccc2n1C
Show InChI InChI=1S/C19H22N2/c1-20(13-12-16-8-4-3-5-9-16)15-18-14-17-10-6-7-11-19(17)21(18)2/h3-11,14H,12-13,15H2,1-2H3
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7n/an/an/an/an/an/an/an/a



Sapienza Università di Roma

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Monoamine oxidase


(Bos taurus)
BDBM50273528
PNG
(CHEMBL460608 | N-Methyl,N-(2-phenylethyl)-1H-indol...)
Show SMILES CN(CCc1ccccc1)C(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C18H18N2O/c1-20(12-11-14-7-3-2-4-8-14)18(21)17-13-15-9-5-6-10-16(15)19-17/h2-10,13,19H,11-12H2,1H3
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100n/an/an/an/an/an/an/an/a



Sapienza Università di Roma

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-B by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Monoamine oxidase


(Bos taurus)
BDBM50273594
PNG
(CHEMBL446960 | N-((1H-indol-2-yl)methyl)-2-phenyle...)
Show SMILES C(Cc1ccccc1)NCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C17H18N2/c1-2-6-14(7-3-1)10-11-18-13-16-12-15-8-4-5-9-17(15)19-16/h1-9,12,18-19H,10-11,13H2
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1.60E+3n/an/an/an/an/an/an/an/a



Sapienza Università di Roma

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Monoamine oxidase


(Bos taurus)
BDBM50273620
PNG
(CHEMBL460828 | N-(1-Methyl-1H-indol-2-ylmethyl)-N-...)
Show SMILES CN(CCc1ccccc1)Cc1cc2ccccc2n1C
Show InChI InChI=1S/C19H22N2/c1-20(13-12-16-8-4-3-5-9-16)15-18-14-17-10-6-7-11-19(17)21(18)2/h3-11,14H,12-13,15H2,1-2H3
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2.50E+4n/an/an/an/an/an/an/an/a



Sapienza Università di Roma

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-B by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Monoamine oxidase


(Bos taurus)
BDBM50273594
PNG
(CHEMBL446960 | N-((1H-indol-2-yl)methyl)-2-phenyle...)
Show SMILES C(Cc1ccccc1)NCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C17H18N2/c1-2-6-14(7-3-1)10-11-18-13-16-12-15-8-4-5-9-17(15)19-16/h1-9,12,18-19H,10-11,13H2
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>1.00E+5n/an/an/an/an/an/an/an/a



Sapienza Università di Roma

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-B by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50273528
PNG
(CHEMBL460608 | N-Methyl,N-(2-phenylethyl)-1H-indol...)
Show SMILES CN(CCc1ccccc1)C(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C18H18N2O/c1-20(12-11-14-7-3-2-4-8-14)18(21)17-13-15-9-5-6-10-16(15)19-17/h2-10,13,19H,11-12H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.00E+6n/an/an/an/an/an/an/an/a



Bharati Vidyapeeth Deemed University

Curated by ChEMBL


Assay Description
Inhibition of MAO-A receptor


Bioorg Med Chem Lett 21: 2419-24 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.072
BindingDB Entry DOI: 10.7270/Q2QZ2C6S
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50273620
PNG
(CHEMBL460828 | N-(1-Methyl-1H-indol-2-ylmethyl)-N-...)
Show SMILES CN(CCc1ccccc1)Cc1cc2ccccc2n1C
Show InChI InChI=1S/C19H22N2/c1-20(13-12-16-8-4-3-5-9-16)15-18-14-17-10-6-7-11-19(17)21(18)2/h3-11,14H,12-13,15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem

Similars

Article
PubMed
7.00E+6n/an/an/an/an/an/an/an/a



Bharati Vidyapeeth Deemed University

Curated by ChEMBL


Assay Description
Inhibition of MAO-A receptor


Bioorg Med Chem Lett 21: 2419-24 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.072
BindingDB Entry DOI: 10.7270/Q2QZ2C6S
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50273594
PNG
(CHEMBL446960 | N-((1H-indol-2-yl)methyl)-2-phenyle...)
Show SMILES C(Cc1ccccc1)NCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C17H18N2/c1-2-6-14(7-3-1)10-11-18-13-16-12-15-8-4-5-9-17(15)19-16/h1-9,12,18-19H,10-11,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.60E+9n/an/an/an/an/an/an/an/a



Bharati Vidyapeeth Deemed University

Curated by ChEMBL


Assay Description
Inhibition of MAO-A receptor


Bioorg Med Chem Lett 21: 2419-24 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.072
BindingDB Entry DOI: 10.7270/Q2QZ2C6S
More data for this
Ligand-Target Pair