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2 similar compounds to monomer 50276289

Compile data set for download or QSAR
Wt: 333.3
BDBM50276353
Wt: 347.3
BDBM50276354

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276353,50276354   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens)
BDBM50276354
PNG
(3'-fluoro-N,N-dimethyl-4'-(trifluoromethyl)bipheny...)
Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F
Show InChI InChI=1S/C15H13F4NO2S/c1-20(2)23(21,22)12-6-3-10(4-7-12)11-5-8-13(14(16)9-11)15(17,18)19/h3-9H,1-2H3
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



University of Shizuoka

Curated by ChEMBL


Assay Description
Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay


Bioorg Med Chem Lett 19: 1058-61 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.018
BindingDB Entry DOI: 10.7270/Q20R9P8G
More data for this
Ligand-Target Pair
Kinesin-like protein 1


(Homo sapiens)
BDBM50276353
PNG
(3'-fluoro-N-methyl-4'-(trifluoromethyl)biphenyl-4-...)
Show SMILES CNS(=O)(=O)c1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F
Show InChI InChI=1S/C14H11F4NO2S/c1-19-22(20,21)11-5-2-9(3-6-11)10-4-7-12(13(15)8-10)14(16,17)18/h2-8,19H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.61E+3n/an/an/an/an/an/a



University of Shizuoka

Curated by ChEMBL


Assay Description
Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay


Bioorg Med Chem Lett 19: 1058-61 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.018
BindingDB Entry DOI: 10.7270/Q20R9P8G
More data for this
Ligand-Target Pair