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2 similar compounds to monomer 50391109

Compile data set for download or QSAR
Wt: 117.9
BDBM50284960
Wt: 115.9
BDBM50433177

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50284960,50433177   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-tyrosine phosphatase 1B


(Homo sapiens (human))
BDBM50433177
PNG
(SODIUM ORTHOVANADATE)
Show SMILES O[V]([O-])([O-])=O
Show InChI InChI=1S/H2O.3O.V/h1H2;;;;/q;;2*-1;+1/p-1
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
670n/an/an/an/an/an/an/an/a



Aurigene Discovery Technologies Limited

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) expressed in Escherichia coli assessed as conversion of pNPP to 4-nitrophenol


Bioorg Med Chem Lett 23: 2579-84 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.109
BindingDB Entry DOI: 10.7270/Q2CJ8FV5
More data for this
Ligand-Target Pair
Probable low molecular weight protein-tyrosine-phosphatase


(Mycobacterium tuberculosis)
BDBM50284960
PNG
(CHEMBL50626 | H3VO4 | Vanadiumsaeure | [VO(OH)3] |...)
Show SMILES O[V](O)(O)=O
Show InChI InChI=1S/3H2O.O.V/h3*1H2;;/q;;;;+3/p-3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



Universidade Federal de Santa Catarina

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis PTPA


Bioorg Med Chem 18: 3783-9 (2010)


Article DOI: 10.1016/j.bmc.2010.04.051
BindingDB Entry DOI: 10.7270/Q2MW2J4B
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (human))
BDBM50433177
PNG
(SODIUM ORTHOVANADATE)
Show SMILES O[V]([O-])([O-])=O
Show InChI InChI=1S/H2O.3O.V/h1H2;;;;/q;;2*-1;+1/p-1
PDB
MMDB

NCI pathway
Reactome pathway
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UniProtKB/SwissProt

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PC sid
UniChem

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Article
PubMed
n/an/a 8.54E+3n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) expressed in Escherichia coli expression system using p-nitrophenyl phosphate as substrate assessed as release o...


Eur J Med Chem 63: 511-22 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.001
BindingDB Entry DOI: 10.7270/Q27S7Q59
More data for this
Ligand-Target Pair
Prostatic acid phosphatase


(Homo sapiens)
BDBM50284960
PNG
(CHEMBL50626 | H3VO4 | Vanadiumsaeure | [VO(OH)3] |...)
Show SMILES O[V](O)(O)=O
Show InChI InChI=1S/3H2O.O.V/h3*1H2;;/q;;;;+3/p-3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 3.40E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for 50% of inhibition of Osteoclastic acid phosphatase (OAP) activity, determined using dose-response curve


Bioorg Med Chem Lett 5: 1801-1806 (1995)


Article DOI: 10.1016/0960-894X(95)00299-9
BindingDB Entry DOI: 10.7270/Q2CC10NQ
More data for this
Ligand-Target Pair