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2 similar compounds to monomer 50289001

Wt: 379.1
BDBM50289011
Wt: 379.1
BDBM50289015

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50289011,50289015   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement C1r subcomponent


(Homo sapiens (Human))
BDBM50289011
PNG
(2-(2-Iodo-phenyl)-6-methoxy-benzo[d][1,3]oxazin-4-...)
Show SMILES COc1ccc2nc(oc(=O)c2c1)-c1ccccc1I
Show InChI InChI=1S/C15H10INO3/c1-19-9-6-7-13-11(8-9)15(18)20-14(17-13)10-4-2-3-5-12(10)16/h2-8H,1H3
PDB
MMDB

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Article
n/an/a>6.25E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of C1r serine protease


Bioorg Med Chem Lett 6: 679-682 (1996)


Article DOI: 10.1016/0960-894X(96)00094-7
BindingDB Entry DOI: 10.7270/Q2P84BVF
More data for this
Ligand-Target Pair
Complement C1r subcomponent


(Homo sapiens (Human))
BDBM50289015
PNG
(2-(2-Iodo-phenyl)-7-methoxy-benzo[d][1,3]oxazin-4-...)
Show SMILES COc1ccc2c(c1)nc(oc2=O)-c1ccccc1I
Show InChI InChI=1S/C15H10INO3/c1-19-9-6-7-11-13(8-9)17-14(20-15(11)18)10-4-2-3-5-12(10)16/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Article
n/an/a>6.25E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against C1r serine protease


Bioorg Med Chem Lett 6: 679-682 (1996)


Article DOI: 10.1016/0960-894X(96)00094-7
BindingDB Entry DOI: 10.7270/Q2P84BVF
More data for this
Ligand-Target Pair
Complement C1r


(Homo sapiens (Human))
BDBM50289015
PNG
(2-(2-Iodo-phenyl)-7-methoxy-benzo[d][1,3]oxazin-4-...)
Show SMILES COc1ccc2c(c1)nc(oc2=O)-c1ccccc1I
Show InChI InChI=1S/C15H10INO3/c1-19-9-6-7-11-13(8-9)17-14(20-15(11)18)10-4-2-3-5-12(10)16/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>6.25E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against C1r serine protease


Bioorg Med Chem Lett 6: 679-682 (1996)


Article DOI: 10.1016/0960-894X(96)00094-7
BindingDB Entry DOI: 10.7270/Q2P84BVF
More data for this
Ligand-Target Pair
Complement C1r


(Homo sapiens (Human))
BDBM50289011
PNG
(2-(2-Iodo-phenyl)-6-methoxy-benzo[d][1,3]oxazin-4-...)
Show SMILES COc1ccc2nc(oc(=O)c2c1)-c1ccccc1I
Show InChI InChI=1S/C15H10INO3/c1-19-9-6-7-13-11(8-9)15(18)20-14(17-13)10-4-2-3-5-12(10)16/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>6.25E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against C1r serine protease


Bioorg Med Chem Lett 6: 679-682 (1996)


Article DOI: 10.1016/0960-894X(96)00094-7
BindingDB Entry DOI: 10.7270/Q2P84BVF
More data for this
Ligand-Target Pair
Complement C1r


(Homo sapiens (Human))
BDBM50289011
PNG
(2-(2-Iodo-phenyl)-6-methoxy-benzo[d][1,3]oxazin-4-...)
Show SMILES COc1ccc2nc(oc(=O)c2c1)-c1ccccc1I
Show InChI InChI=1S/C15H10INO3/c1-19-9-6-7-13-11(8-9)15(18)20-14(17-13)10-4-2-3-5-12(10)16/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against C1r serine protease


Bioorg Med Chem Lett 6: 679-682 (1996)


Article DOI: 10.1016/0960-894X(96)00094-7
BindingDB Entry DOI: 10.7270/Q2P84BVF
More data for this
Ligand-Target Pair