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20 similar compounds to monomer 50303527

Compile data set for download or QSAR
Wt: 283.4
BDBM50303524
Wt: 297.4
BDBM50303525
Wt: 311.4
BDBM50303526
Purchase
Wt: 285.3
BDBM50303528
Wt: 299.4
BDBM50303529
Wt: 313.4
BDBM50303530
Wt: 327.4
BDBM50303531
Purchase
Wt: 313.4
BDBM50303533
Wt: 343.5
BDBM50303534
Wt: 313.3
BDBM50303535
Wt: 312.4
BDBM50303536
Wt: 339.4
BDBM50303538
Wt: 331.4
BDBM50303539
Wt: 346.4
BDBM50303543
Wt: 346.4
BDBM50303544
Displayed 1 to 15 (of 20 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 48 hits for monomerid = 50303524,50303525,50303526,50303528,50303529,50303530,50303531,50303533,50303534,50303535,50303536,50303538,50303539,50303543,50303544   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303534
PNG
((1-(4-(Methylthio)butyl)-1H-indol-3-yl)(2,2,3,3-te...)
Show SMILES CSCCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C21H29NOS/c1-20(2)19(21(20,3)4)18(23)16-14-22(12-8-9-13-24-5)17-11-7-6-10-15(16)17/h6-7,10-11,14,19H,8-9,12-13H2,1-5H3
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0.400n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303531
PNG
((1-(5-Hydroxypentyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C21H29NO2/c1-20(2)19(21(20,3)4)18(24)16-14-22(12-8-5-9-13-23)17-11-7-6-10-15(16)17/h6-7,10-11,14,19,23H,5,8-9,12-13H2,1-4H3
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0.710n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303538
PNG
(6-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1H-...)
Show SMILES CC(=O)CCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C22H29NO2/c1-15(24)10-8-9-13-23-14-17(16-11-6-7-12-18(16)23)19(25)20-21(2,3)22(20,4)5/h6-7,11-12,14,20H,8-10,13H2,1-5H3
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0.990n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303533
PNG
((1-(3-Methoxypropyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES COCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(22)15-13-21(11-8-12-23-5)16-10-7-6-9-14(15)16/h6-7,9-10,13,18H,8,11-12H2,1-5H3
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1.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303526
PNG
((1-Pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CCCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C21H29NO/c1-6-7-10-13-22-14-16(15-11-8-9-12-17(15)22)18(23)19-20(2,3)21(19,4)5/h8-9,11-12,14,19H,6-7,10,13H2,1-5H3
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1.80n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303525
PNG
((1-Butyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopr...)
Show SMILES CCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C20H27NO/c1-6-7-12-21-13-15(14-10-8-9-11-16(14)21)17(22)18-19(2,3)20(18,4)5/h8-11,13,18H,6-7,12H2,1-5H3
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2n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303529
PNG
((1-(3-Hydroxypropyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C19H25NO2/c1-18(2)17(19(18,3)4)16(22)14-12-20(10-7-11-21)15-9-6-5-8-13(14)15/h5-6,8-9,12,17,21H,7,10-11H2,1-4H3
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2.10n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303530
PNG
((1-(4-Hydroxybutyl)-1H-indol-3-yl)(2,2,3,3-tetrame...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(23)15-13-21(11-7-8-12-22)16-10-6-5-9-14(15)16/h5-6,9-10,13,18,22H,7-8,11-12H2,1-4H3
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2.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303539
PNG
((1-Benzyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CC1(C)C(C(=O)c2cn(Cc3ccccc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H25NO/c1-22(2)21(23(22,3)4)20(25)18-15-24(14-16-10-6-5-7-11-16)19-13-9-8-12-17(18)19/h5-13,15,21H,14H2,1-4H3
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8.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303524
PNG
((1-Propyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C19H25NO/c1-6-11-20-12-14(13-9-7-8-10-15(13)20)16(21)17-18(2,3)19(17,4)5/h7-10,12,17H,6,11H2,1-5H3
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9.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303543
PNG
((1-(2-(Pyridin-3-yl)ethyl)-1H-indol-3-yl)(2,2,3,3-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCc3cccnc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H26N2O/c1-22(2)21(23(22,3)4)20(26)18-15-25(19-10-6-5-9-17(18)19)13-11-16-8-7-12-24-14-16/h5-10,12,14-15,21H,11,13H2,1-4H3
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20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303544
PNG
((1-(2-(Pyridin-4-yl)ethyl)-1H-indol-3-yl)(2,2,3,3-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCc3ccncc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H26N2O/c1-22(2)21(23(22,3)4)20(26)18-15-25(19-8-6-5-7-17(18)19)14-11-16-9-12-24-13-10-16/h5-10,12-13,15,21H,11,14H2,1-4H3
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31n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303534
PNG
((1-(4-(Methylthio)butyl)-1H-indol-3-yl)(2,2,3,3-te...)
Show SMILES CSCCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C21H29NOS/c1-20(2)19(21(20,3)4)18(23)16-14-22(12-8-9-13-24-5)17-11-7-6-10-15(16)17/h6-7,10-11,14,19H,8-9,12-13H2,1-5H3
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39n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303528
PNG
(CHEMBL576920 | [1-(2-Hydroxyethyl)-1H-indol-3-yl](...)
Show SMILES CC1(C)C(C(=O)c2cn(CCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C18H23NO2/c1-17(2)16(18(17,3)4)15(21)13-11-19(9-10-20)14-8-6-5-7-12(13)14/h5-8,11,16,20H,9-10H2,1-4H3
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56n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303525
PNG
((1-Butyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopr...)
Show SMILES CCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C20H27NO/c1-6-7-12-21-13-15(14-10-8-9-11-16(14)21)17(22)18-19(2,3)20(18,4)5/h8-11,13,18H,6-7,12H2,1-5H3
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91n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303526
PNG
((1-Pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CCCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C21H29NO/c1-6-7-10-13-22-14-16(15-11-8-9-12-17(15)22)18(23)19-20(2,3)21(19,4)5/h8-9,11-12,14,19H,6-7,10,13H2,1-5H3
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150n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303539
PNG
((1-Benzyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CC1(C)C(C(=O)c2cn(Cc3ccccc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H25NO/c1-22(2)21(23(22,3)4)20(25)18-15-24(14-16-10-6-5-7-11-16)19-13-9-8-12-17(18)19/h5-13,15,21H,14H2,1-4H3
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210n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303536
PNG
(3-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1H-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCC(N)=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C19H24N2O2/c1-18(2)17(19(18,3)4)16(23)13-11-21(10-9-15(20)22)14-8-6-5-7-12(13)14/h5-8,11,17H,9-10H2,1-4H3,(H2,20,22)
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220n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303538
PNG
(6-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1H-...)
Show SMILES CC(=O)CCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C22H29NO2/c1-15(24)10-8-9-13-23-14-17(16-11-6-7-12-18(16)23)19(25)20-21(2,3)22(20,4)5/h6-7,11-12,14,20H,8-10,13H2,1-5H3
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380n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303533
PNG
((1-(3-Methoxypropyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES COCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(22)15-13-21(11-8-12-23-5)16-10-7-6-9-14(15)16/h6-7,9-10,13,18H,8,11-12H2,1-5H3
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660n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303531
PNG
((1-(5-Hydroxypentyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C21H29NO2/c1-20(2)19(21(20,3)4)18(24)16-14-22(12-8-5-9-13-23)17-11-7-6-10-15(16)17/h6-7,10-11,14,19,23H,5,8-9,12-13H2,1-4H3
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680n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303535
PNG
(3-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1H-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCC(O)=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C19H23NO3/c1-18(2)17(19(18,3)4)16(23)13-11-20(10-9-15(21)22)14-8-6-5-7-12(13)14/h5-8,11,17H,9-10H2,1-4H3,(H,21,22)
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>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303544
PNG
((1-(2-(Pyridin-4-yl)ethyl)-1H-indol-3-yl)(2,2,3,3-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCc3ccncc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H26N2O/c1-22(2)21(23(22,3)4)20(26)18-15-25(19-8-6-5-7-17(18)19)14-11-16-9-12-24-13-10-16/h5-10,12-13,15,21H,11,14H2,1-4H3
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2.20E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303529
PNG
((1-(3-Hydroxypropyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C19H25NO2/c1-18(2)17(19(18,3)4)16(22)14-12-20(10-7-11-21)15-9-6-5-8-13(14)15/h5-6,8-9,12,17,21H,7,10-11H2,1-4H3
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2.20E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303524
PNG
((1-Propyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C19H25NO/c1-6-11-20-12-14(13-9-7-8-10-15(13)20)16(21)17-18(2,3)19(17,4)5/h7-10,12,17H,6,11H2,1-5H3
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4.30E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303530
PNG
((1-(4-Hydroxybutyl)-1H-indol-3-yl)(2,2,3,3-tetrame...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(23)15-13-21(11-7-8-12-22)16-10-6-5-9-14(15)16/h5-6,9-10,13,18,22H,7-8,11-12H2,1-4H3
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>5.60E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303528
PNG
(CHEMBL576920 | [1-(2-Hydroxyethyl)-1H-indol-3-yl](...)
Show SMILES CC1(C)C(C(=O)c2cn(CCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C18H23NO2/c1-17(2)16(18(17,3)4)15(21)13-11-19(9-10-20)14-8-6-5-7-12(13)14/h5-8,11,16,20H,9-10H2,1-4H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303543
PNG
((1-(2-(Pyridin-3-yl)ethyl)-1H-indol-3-yl)(2,2,3,3-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCc3cccnc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H26N2O/c1-22(2)21(23(22,3)4)20(26)18-15-25(19-10-6-5-9-17(18)19)13-11-16-8-7-12-24-14-16/h5-10,12,14-15,21H,11,13H2,1-4H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303536
PNG
(3-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1H-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCC(N)=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C19H24N2O2/c1-18(2)17(19(18,3)4)16(23)13-11-21(10-9-15(20)22)14-8-6-5-7-12(13)14/h5-8,11,17H,9-10H2,1-4H3,(H2,20,22)
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303535
PNG
(3-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1H-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCC(O)=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C19H23NO3/c1-18(2)17(19(18,3)4)16(23)13-11-20(10-9-15(21)22)14-8-6-5-7-12(13)14/h5-8,11,17H,9-10H2,1-4H3,(H,21,22)
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303530
PNG
((1-(4-Hydroxybutyl)-1H-indol-3-yl)(2,2,3,3-tetrame...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(23)15-13-21(11-7-8-12-22)16-10-6-5-9-14(15)16/h5-6,9-10,13,18,22H,7-8,11-12H2,1-4H3
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n/an/an/an/a 2.10n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50303530
PNG
((1-(4-Hydroxybutyl)-1H-indol-3-yl)(2,2,3,3-tetrame...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(23)15-13-21(11-7-8-12-22)16-10-6-5-9-14(15)16/h5-6,9-10,13,18,22H,7-8,11-12H2,1-4H3
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n/an/an/an/a 2.08E+3n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at rat CB1 receptor assessed as inhibition of forskolin-induced cAMP production by cell based assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303530
PNG
((1-(4-Hydroxybutyl)-1H-indol-3-yl)(2,2,3,3-tetrame...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(23)15-13-21(11-7-8-12-22)16-10-6-5-9-14(15)16/h5-6,9-10,13,18,22H,7-8,11-12H2,1-4H3
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n/an/an/an/a 1.88E+3n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303544
PNG
((1-(2-(Pyridin-4-yl)ethyl)-1H-indol-3-yl)(2,2,3,3-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCc3ccncc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H26N2O/c1-22(2)21(23(22,3)4)20(26)18-15-25(19-8-6-5-7-17(18)19)14-11-16-9-12-24-13-10-16/h5-10,12-13,15,21H,11,14H2,1-4H3
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n/an/an/an/a 162n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303543
PNG
((1-(2-(Pyridin-3-yl)ethyl)-1H-indol-3-yl)(2,2,3,3-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCc3cccnc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H26N2O/c1-22(2)21(23(22,3)4)20(26)18-15-25(19-10-6-5-9-17(18)19)13-11-16-8-7-12-24-14-16/h5-10,12,14-15,21H,11,13H2,1-4H3
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n/an/an/an/a 62n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303539
PNG
((1-Benzyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CC1(C)C(C(=O)c2cn(Cc3ccccc3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C23H25NO/c1-22(2)21(23(22,3)4)20(25)18-15-24(14-16-10-6-5-7-11-16)19-13-9-8-12-17(18)19/h5-13,15,21H,14H2,1-4H3
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n/an/an/an/a 93n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303538
PNG
(6-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1H-...)
Show SMILES CC(=O)CCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C22H29NO2/c1-15(24)10-8-9-13-23-14-17(16-11-6-7-12-18(16)23)19(25)20-21(2,3)22(20,4)5/h6-7,11-12,14,20H,8-10,13H2,1-5H3
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n/an/an/an/a 6n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303536
PNG
(3-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1H-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCC(N)=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C19H24N2O2/c1-18(2)17(19(18,3)4)16(23)13-11-21(10-9-15(20)22)14-8-6-5-7-12(13)14/h5-8,11,17H,9-10H2,1-4H3,(H2,20,22)
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n/an/an/an/a 294n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303534
PNG
((1-(4-(Methylthio)butyl)-1H-indol-3-yl)(2,2,3,3-te...)
Show SMILES CSCCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C21H29NOS/c1-20(2)19(21(20,3)4)18(23)16-14-22(12-8-9-13-24-5)17-11-7-6-10-15(16)17/h6-7,10-11,14,19H,8-9,12-13H2,1-5H3
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n/an/an/an/a 22n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303533
PNG
((1-(3-Methoxypropyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES COCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(22)15-13-21(11-8-12-23-5)16-10-7-6-9-14(15)16/h6-7,9-10,13,18H,8,11-12H2,1-5H3
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n/an/an/an/a 26n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303531
PNG
((1-(5-Hydroxypentyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C21H29NO2/c1-20(2)19(21(20,3)4)18(24)16-14-22(12-8-5-9-13-23)17-11-7-6-10-15(16)17/h6-7,10-11,14,19,23H,5,8-9,12-13H2,1-4H3
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n/an/an/an/a 11n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303530
PNG
((1-(4-Hydroxybutyl)-1H-indol-3-yl)(2,2,3,3-tetrame...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(23)15-13-21(11-7-8-12-22)16-10-6-5-9-14(15)16/h5-6,9-10,13,18,22H,7-8,11-12H2,1-4H3
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n/an/an/an/a 8n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303529
PNG
((1-(3-Hydroxypropyl)-1H-indol-3-yl)(2,2,3,3-tetram...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C19H25NO2/c1-18(2)17(19(18,3)4)16(22)14-12-20(10-7-11-21)15-9-6-5-8-13(14)15/h5-6,8-9,12,17,21H,7,10-11H2,1-4H3
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n/an/an/an/a 27n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303528
PNG
(CHEMBL576920 | [1-(2-Hydroxyethyl)-1H-indol-3-yl](...)
Show SMILES CC1(C)C(C(=O)c2cn(CCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C18H23NO2/c1-17(2)16(18(17,3)4)15(21)13-11-19(9-10-20)14-8-6-5-7-12(13)14/h5-8,11,16,20H,9-10H2,1-4H3
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n/an/an/an/a 440n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303526
PNG
((1-Pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CCCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C21H29NO/c1-6-7-10-13-22-14-16(15-11-8-9-12-17(15)22)18(23)19-20(2,3)21(19,4)5/h8-9,11-12,14,19H,6-7,10,13H2,1-5H3
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n/an/an/an/a 29n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303524
PNG
((1-Propyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C19H25NO/c1-6-11-20-12-14(13-9-7-8-10-15(13)20)16(21)17-18(2,3)19(17,4)5/h7-10,12,17H,6,11H2,1-5H3
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n/an/an/an/a 36n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM50303530
PNG
((1-(4-Hydroxybutyl)-1H-indol-3-yl)(2,2,3,3-tetrame...)
Show SMILES CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C
Show InChI InChI=1S/C20H27NO2/c1-19(2)18(20(19,3)4)17(23)15-13-21(11-7-8-12-22)16-10-6-5-9-14(15)16/h5-6,9-10,13,18,22H,7-8,11-12H2,1-4H3
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n/an/an/an/a 4.40n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at rat CB2 receptor assessed as inhibition of forskolin-induced cAMP production by cell based assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303525
PNG
((1-Butyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopr...)
Show SMILES CCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C20H27NO/c1-6-7-12-21-13-15(14-10-8-9-11-16(14)21)17(22)18-19(2,3)20(18,4)5/h8-11,13,18H,6-7,12H2,1-5H3
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n/an/an/an/a 5n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair