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10 similar compounds to monomer 50306819

Compile data set for download or QSAR
Wt: 464.6
BDBM50306818
Wt: 506.7
BDBM50306838
Wt: 536.7
BDBM50306839
Wt: 493.6
BDBM50306852
Wt: 454.5
BDBM50357975
Wt: 440.5
BDBM50357978
Wt: 454.5
BDBM50357979
Wt: 482.6
BDBM50357988
Wt: 468.6
BDBM50357989
Wt: 482.6
BDBM50357991

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50306818,50306838,50306839,50306852,50357975,50357978,50357979,50357988,50357989,50357991   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50357975
PNG
(CHEMBL1917341)
Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2cnc3ccccc3c2)CC1
Show InChI InChI=1S/C24H30N4O3S/c1-31-24-11-5-4-10-23(24)28-16-14-27(15-17-28)13-7-6-12-26-32(29,30)21-18-20-8-2-3-9-22(20)25-19-21/h2-5,8-11,18-19,26H,6-7,12-17H2,1H3
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3.70n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50357988
PNG
(CHEMBL1917354)
Show SMILES CCN(CCCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1cnc2ccccc2c1
Show InChI InChI=1S/C26H34N4O3S/c1-3-30(34(31,32)23-20-22-10-4-5-11-24(22)27-21-23)15-9-8-14-28-16-18-29(19-17-28)25-12-6-7-13-26(25)33-2/h4-7,10-13,20-21H,3,8-9,14-19H2,1-2H3
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9.30n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50357989
PNG
(CHEMBL1917355)
Show SMILES CCN(CCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C25H32N4O3S/c1-3-29(33(30,31)22-11-12-23-21(20-22)8-6-13-26-23)15-7-14-27-16-18-28(19-17-27)24-9-4-5-10-25(24)32-2/h4-6,8-13,20H,3,7,14-19H2,1-2H3
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25n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50357989
PNG
(CHEMBL1917355)
Show SMILES CCN(CCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C25H32N4O3S/c1-3-29(33(30,31)22-11-12-23-21(20-22)8-6-13-26-23)15-7-14-27-16-18-28(19-17-27)24-9-4-5-10-25(24)32-2/h4-6,8-13,20H,3,7,14-19H2,1-2H3
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29n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50357991
PNG
(CHEMBL1917357)
Show SMILES CCN(CCCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1cccc2cccnc12
Show InChI InChI=1S/C26H34N4O3S/c1-3-30(34(31,32)25-14-8-10-22-11-9-15-27-26(22)25)17-7-6-16-28-18-20-29(21-19-28)23-12-4-5-13-24(23)33-2/h4-5,8-15H,3,6-7,16-21H2,1-2H3
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30n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50357991
PNG
(CHEMBL1917357)
Show SMILES CCN(CCCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1cccc2cccnc12
Show InChI InChI=1S/C26H34N4O3S/c1-3-30(34(31,32)25-14-8-10-22-11-9-15-27-26(22)25)17-7-6-16-28-18-20-29(21-19-28)23-12-4-5-13-24(23)33-2/h4-5,8-15H,3,6-7,16-21H2,1-2H3
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37n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50357978
PNG
(CHEMBL1917344)
Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C23H28N4O3S/c1-30-21-10-3-2-9-20(21)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-11-4-7-19-8-5-12-24-23(19)22/h2-5,7-12,25H,6,13-18H2,1H3
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37n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50357988
PNG
(CHEMBL1917354)
Show SMILES CCN(CCCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1cnc2ccccc2c1
Show InChI InChI=1S/C26H34N4O3S/c1-3-30(34(31,32)23-20-22-10-4-5-11-24(22)27-21-23)15-9-8-14-28-16-18-29(19-17-28)25-12-6-7-13-26(25)33-2/h4-7,10-13,20-21H,3,8-9,14-19H2,1-2H3
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38n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50357979
PNG
(CHEMBL1917345)
Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C24H30N4O3S/c1-31-22-11-3-2-10-21(22)28-18-16-27(17-19-28)15-5-4-14-26-32(29,30)23-12-6-8-20-9-7-13-25-24(20)23/h2-3,6-13,26H,4-5,14-19H2,1H3
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53n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50357979
PNG
(CHEMBL1917345)
Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C24H30N4O3S/c1-31-22-11-3-2-10-21(22)28-18-16-27(17-19-28)15-5-4-14-26-32(29,30)23-12-6-8-20-9-7-13-25-24(20)23/h2-3,6-13,26H,4-5,14-19H2,1H3
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55n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50357975
PNG
(CHEMBL1917341)
Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2cnc3ccccc3c2)CC1
Show InChI InChI=1S/C24H30N4O3S/c1-31-24-11-5-4-10-23(24)28-16-14-27(15-17-28)13-7-6-12-26-32(29,30)21-18-20-8-2-3-9-22(20)25-19-21/h2-5,8-11,18-19,26H,6-7,12-17H2,1H3
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79n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50357978
PNG
(CHEMBL1917344)
Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C23H28N4O3S/c1-30-21-10-3-2-9-20(21)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-11-4-7-19-8-5-12-24-23(19)22/h2-5,7-12,25H,6,13-18H2,1H3
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90n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50357989
PNG
(CHEMBL1917355)
Show SMILES CCN(CCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C25H32N4O3S/c1-3-29(33(30,31)22-11-12-23-21(20-22)8-6-13-26-23)15-7-14-27-16-18-28(19-17-27)24-9-4-5-10-25(24)32-2/h4-6,8-13,20H,3,7,14-19H2,1-2H3
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1.32E+3n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-ketanserin from 5-HT2A receptor in rat cortex by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50357978
PNG
(CHEMBL1917344)
Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C23H28N4O3S/c1-30-21-10-3-2-9-20(21)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-11-4-7-19-8-5-12-24-23(19)22/h2-5,7-12,25H,6,13-18H2,1H3
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1.64E+3n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-ketanserin from 5-HT2A receptor in rat cortex by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50357989
PNG
(CHEMBL1917355)
Show SMILES CCN(CCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C25H32N4O3S/c1-3-29(33(30,31)22-11-12-23-21(20-22)8-6-13-26-23)15-7-14-27-16-18-28(19-17-27)24-9-4-5-10-25(24)32-2/h4-6,8-13,20H,3,7,14-19H2,1-2H3
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1.92E+3n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50357978
PNG
(CHEMBL1917344)
Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C23H28N4O3S/c1-30-21-10-3-2-9-20(21)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-11-4-7-19-8-5-12-24-23(19)22/h2-5,7-12,25H,6,13-18H2,1H3
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2.16E+3n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting


Bioorg Med Chem 19: 6750-9 (2011)


Article DOI: 10.1016/j.bmc.2011.09.044
BindingDB Entry DOI: 10.7270/Q2028S0V
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50306839
PNG
(CHEMBL601885 | N-(Cyclohexylmethyl)-N-[3-(4-(2-met...)
Show SMILES COc1ccccc1N1CCN(CCCN(CC2CCCCC2)S(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C30H40N4O3S/c1-37-28-15-6-5-14-27(28)33-22-20-32(21-23-33)18-9-19-34(24-25-10-3-2-4-11-25)38(35,36)29-16-7-12-26-13-8-17-31-30(26)29/h5-8,12-17,25H,2-4,9-11,18-24H2,1H3
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n/an/a 59.9n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50306838
PNG
(CHEMBL602285 | N-(Cyclohexylmethyl)-N-(3-(4-phenyl...)
Show SMILES O=S(=O)(N(CCCN1CCN(CC1)c1ccccc1)CC1CCCCC1)c1cccc2cccnc12
Show InChI InChI=1S/C29H38N4O2S/c34-36(35,28-16-7-12-26-13-8-17-30-29(26)28)33(24-25-10-3-1-4-11-25)19-9-18-31-20-22-32(23-21-31)27-14-5-2-6-15-27/h2,5-8,12-17,25H,1,3-4,9-11,18-24H2
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n/an/a 34.6n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50306818
PNG
(CHEMBL600607 | N-(Cyclopropylmethyl)-N-(3-(4-pheny...)
Show SMILES O=S(=O)(N(CCCN1CCN(CC1)c1ccccc1)CC1CC1)c1cccc2cccnc12
Show InChI InChI=1S/C26H32N4O2S/c31-33(32,25-11-4-7-23-8-5-14-27-26(23)25)30(21-22-12-13-22)16-6-15-28-17-19-29(20-18-28)24-9-2-1-3-10-24/h1-5,7-11,14,22H,6,12-13,15-21H2
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n/an/a 749n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50306852
PNG
(CHEMBL603272 | N-(Cyclopropylmethyl)-N-(3-(4-(2-me...)
Show SMILES COc1ccccc1N1CCN(CCCN(CC2CC2)S(=O)(=O)c2ccc3ccccc3c2)CC1
Show InChI InChI=1S/C28H35N3O3S/c1-34-28-10-5-4-9-27(28)30-19-17-29(18-20-30)15-6-16-31(22-23-11-12-23)35(32,33)26-14-13-24-7-2-3-8-25(24)21-26/h2-5,7-10,13-14,21,23H,6,11-12,15-20,22H2,1H3
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n/an/a 188n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50306839
PNG
(CHEMBL601885 | N-(Cyclohexylmethyl)-N-[3-(4-(2-met...)
Show SMILES COc1ccccc1N1CCN(CCCN(CC2CCCCC2)S(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C30H40N4O3S/c1-37-28-15-6-5-14-27(28)33-22-20-32(21-23-33)18-9-19-34(24-25-10-3-2-4-11-25)38(35,36)29-16-7-12-26-13-8-17-31-30(26)29/h5-8,12-17,25H,2-4,9-11,18-24H2,1H3
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n/an/a 24n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50306852
PNG
(CHEMBL603272 | N-(Cyclopropylmethyl)-N-(3-(4-(2-me...)
Show SMILES COc1ccccc1N1CCN(CCCN(CC2CC2)S(=O)(=O)c2ccc3ccccc3c2)CC1
Show InChI InChI=1S/C28H35N3O3S/c1-34-28-10-5-4-9-27(28)30-19-17-29(18-20-30)15-6-16-31(22-23-11-12-23)35(32,33)26-14-13-24-7-2-3-8-25(24)21-26/h2-5,7-10,13-14,21,23H,6,11-12,15-20,22H2,1H3
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n/an/a 85.8n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50306818
PNG
(CHEMBL600607 | N-(Cyclopropylmethyl)-N-(3-(4-pheny...)
Show SMILES O=S(=O)(N(CCCN1CCN(CC1)c1ccccc1)CC1CC1)c1cccc2cccnc12
Show InChI InChI=1S/C26H32N4O2S/c31-33(32,25-11-4-7-23-8-5-14-27-26(23)25)30(21-22-12-13-22)16-6-15-28-17-19-29(20-18-28)24-9-2-1-3-10-24/h1-5,7-11,14,22H,6,12-13,15-21H2
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n/an/a 2.16E+3n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50306852
PNG
(CHEMBL603272 | N-(Cyclopropylmethyl)-N-(3-(4-(2-me...)
Show SMILES COc1ccccc1N1CCN(CCCN(CC2CC2)S(=O)(=O)c2ccc3ccccc3c2)CC1
Show InChI InChI=1S/C28H35N3O3S/c1-34-28-10-5-4-9-27(28)30-19-17-29(18-20-30)15-6-16-31(22-23-11-12-23)35(32,33)26-14-13-24-7-2-3-8-25(24)21-26/h2-5,7-10,13-14,21,23H,6,11-12,15-20,22H2,1H3
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n/an/a 549n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50306839
PNG
(CHEMBL601885 | N-(Cyclohexylmethyl)-N-[3-(4-(2-met...)
Show SMILES COc1ccccc1N1CCN(CCCN(CC2CCCCC2)S(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C30H40N4O3S/c1-37-28-15-6-5-14-27(28)33-22-20-32(21-23-33)18-9-19-34(24-25-10-3-2-4-11-25)38(35,36)29-16-7-12-26-13-8-17-31-30(26)29/h5-8,12-17,25H,2-4,9-11,18-24H2,1H3
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n/an/a 118n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50306838
PNG
(CHEMBL602285 | N-(Cyclohexylmethyl)-N-(3-(4-phenyl...)
Show SMILES O=S(=O)(N(CCCN1CCN(CC1)c1ccccc1)CC1CCCCC1)c1cccc2cccnc12
Show InChI InChI=1S/C29H38N4O2S/c34-36(35,28-16-7-12-26-13-8-17-30-29(26)28)33(24-25-10-3-1-4-11-25)19-9-18-31-20-22-32(23-21-31)27-14-5-2-6-15-27/h2,5-8,12-17,25H,1,3-4,9-11,18-24H2
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n/an/a 843n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50306818
PNG
(CHEMBL600607 | N-(Cyclopropylmethyl)-N-(3-(4-pheny...)
Show SMILES O=S(=O)(N(CCCN1CCN(CC1)c1ccccc1)CC1CC1)c1cccc2cccnc12
Show InChI InChI=1S/C26H32N4O2S/c31-33(32,25-11-4-7-23-8-5-14-27-26(23)25)30(21-22-12-13-22)16-6-15-28-17-19-29(20-18-28)24-9-2-1-3-10-24/h1-5,7-11,14,22H,6,12-13,15-21H2
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n/an/a 292n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50306838
PNG
(CHEMBL602285 | N-(Cyclohexylmethyl)-N-(3-(4-phenyl...)
Show SMILES O=S(=O)(N(CCCN1CCN(CC1)c1ccccc1)CC1CCCCC1)c1cccc2cccnc12
Show InChI InChI=1S/C29H38N4O2S/c34-36(35,28-16-7-12-26-13-8-17-30-29(26)28)33(24-25-10-3-1-4-11-25)19-9-18-31-20-22-32(23-21-31)27-14-5-2-6-15-27/h2,5-8,12-17,25H,1,3-4,9-11,18-24H2
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n/an/a 419n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair