BindingDB logo
myBDB logout

9 similar compounds to monomer 50311299

Compile data set for download or QSAR
Wt: 271.7
BDBM50311288
Wt: 306.1
BDBM50311290
Wt: 285.7
BDBM50311295
Wt: 285.7
BDBM50311296
Wt: 285.7
BDBM50311297
Wt: 306.1
BDBM50311298
Wt: 306.1
BDBM50311300
Wt: 347.7
BDBM50311302
Wt: 314.7
BDBM50311303

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50311288,50311290,50311295,50311296,50311297,50311298,50311300,50311302,50311303   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311288
PNG
(CHEMBL1078785 | N-(2-chlorophenyl)pyrazolo[1,5-a]p...)
Show SMILES Clc1ccccc1NC(=O)c1cnn2ccccc12
Show InChI InChI=1S/C14H10ClN3O/c15-11-5-1-2-6-12(11)17-14(19)10-9-16-18-8-4-3-7-13(10)18/h1-9H,(H,17,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311290
PNG
(CHEMBL1079075 | N-(2,3-dichlorophenyl)pyrazolo[1,5...)
Show SMILES Clc1cccc(NC(=O)c2cnn3ccccc23)c1Cl
Show InChI InChI=1S/C14H9Cl2N3O/c15-10-4-3-5-11(13(10)16)18-14(20)9-8-17-19-7-2-1-6-12(9)19/h1-8H,(H,18,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311295
PNG
(CHEMBL1080223 | N-(2-chlorophenyl)-4-methylpyrazol...)
Show SMILES Cc1cccn2ncc(C(=O)Nc3ccccc3Cl)c12
Show InChI InChI=1S/C15H12ClN3O/c1-10-5-4-8-19-14(10)11(9-17-19)15(20)18-13-7-3-2-6-12(13)16/h2-9H,1H3,(H,18,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311296
PNG
(CHEMBL1081498 | N-(2-chlorophenyl)-5-methylpyrazol...)
Show SMILES Cc1ccn2ncc(C(=O)Nc3ccccc3Cl)c2c1
Show InChI InChI=1S/C15H12ClN3O/c1-10-6-7-19-14(8-10)11(9-17-19)15(20)18-13-5-3-2-4-12(13)16/h2-9H,1H3,(H,18,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311303
PNG
(CHEMBL1077571 | N-(2-chlorophenyl)-5-(dimethylamin...)
Show SMILES CN(C)c1ccn2ncc(C(=O)Nc3ccccc3Cl)c2c1
Show InChI InChI=1S/C16H15ClN4O/c1-20(2)11-7-8-21-15(9-11)12(10-18-21)16(22)19-14-6-4-3-5-13(14)17/h3-10H,1-2H3,(H,19,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 77n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311298
PNG
(4-chloro-N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine...)
Show SMILES Clc1ccccc1NC(=O)c1cnn2cccc(Cl)c12
Show InChI InChI=1S/C14H9Cl2N3O/c15-10-4-1-2-6-12(10)18-14(20)9-8-17-19-7-3-5-11(16)13(9)19/h1-8H,(H,18,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311300
PNG
(6-chloro-N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine...)
Show SMILES Clc1ccc2c(cnn2c1)C(=O)Nc1ccccc1Cl
Show InChI InChI=1S/C14H9Cl2N3O/c15-9-5-6-13-10(7-17-19(13)8-9)14(20)18-12-4-2-1-3-11(12)16/h1-8H,(H,18,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311302
PNG
(CHEMBL1078107 | N-(2-chlorophenyl)-5-phenylpyrazol...)
Show SMILES Clc1ccccc1NC(=O)c1cnn2ccc(cc12)-c1ccccc1
Show InChI InChI=1S/C20H14ClN3O/c21-17-8-4-5-9-18(17)23-20(25)16-13-22-24-11-10-15(12-19(16)24)14-6-2-1-3-7-14/h1-13H,(H,23,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 66n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311297
PNG
(CHEMBL1081499 | N-(2-chlorophenyl)-6-methylpyrazol...)
Show SMILES Cc1ccc2c(cnn2c1)C(=O)Nc1ccccc1Cl
Show InChI InChI=1S/C15H12ClN3O/c1-10-6-7-14-11(8-17-19(14)9-10)15(20)18-13-5-3-2-4-12(13)16/h2-9H,1H3,(H,18,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair