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2 similar compounds to monomer 24634

Compile data set for download or QSAR
Wt: 271.7
BDBM50311308
Wt: 267.2
BDBM50331283
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311308,50331283   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50331283
PNG
(CHEMBL1288651 | N-(4-methoxyphenyl)-1H-indazole-3-...)
Show SMILES COc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1
Show InChI InChI=1S/C15H13N3O2/c1-20-11-8-6-10(7-9-11)16-15(19)14-12-4-2-3-5-13(12)17-18-14/h2-9H,1H3,(H,16,19)(H,17,18)
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MMDB

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 352n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal GST-tagged FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus expression system using 5-FAM-peptid...


Bioorg Med Chem Lett 26: 2370-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.006
BindingDB Entry DOI: 10.7270/Q2TX3H89
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 2


(Homo sapiens (human))
BDBM50331283
PNG
(CHEMBL1288651 | N-(4-methoxyphenyl)-1H-indazole-3-...)
Show SMILES COc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1
Show InChI InChI=1S/C15H13N3O2/c1-20-11-8-6-10(7-9-11)16-15(19)14-12-4-2-3-5-13(12)17-18-14/h2-9H,1H3,(H,16,19)(H,17,18)
PDB
MMDB

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KEGG

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Nycomed GmbH

Curated by ChEMBL


Assay Description
Inhibition of CDK2


Bioorg Med Chem Lett 20: 6998-7003 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.119
BindingDB Entry DOI: 10.7270/Q2JD4X29
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311308
PNG
(CHEMBL1078238 | N-(2-chlorophenyl)-1H-indazole-3-c...)
Show SMILES Clc1ccccc1NC(=O)c1n[nH]c2ccccc12
Show InChI InChI=1S/C14H10ClN3O/c15-10-6-2-4-8-12(10)16-14(19)13-9-5-1-3-7-11(9)17-18-13/h1-8H,(H,16,19)(H,17,18)
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair