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4 similar compounds to monomer 50271764

Compile data set for download or QSAR
Wt: 219.2
BDBM50313451
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Wt: 205.2
BDBM50313452
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Wt: 219.2
BDBM50313455
Wt: 205.2
BDBM50313459
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50313451,50313452,50313455,50313459   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50313451
PNG
((E)-4-(3,4-dimethylphenylamino)-4-oxobut-2-enoic a...)
Show SMILES Cc1ccc(NC(=O)\C=C\C(O)=O)cc1C
Show InChI InChI=1S/C12H13NO3/c1-8-3-4-10(7-9(8)2)13-11(14)5-6-12(15)16/h3-7H,1-2H3,(H,13,14)(H,15,16)/b6-5+
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CHEMBL
PC cid
PC sid
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Article
PubMed
n/an/a 7.55E+6n/an/an/an/an/an/a



Acadia University

Curated by ChEMBL


Assay Description
Inhibition of human NMT expressed in Escherichia coli DH5alpha cells


Bioorg Med Chem Lett 20: 1510-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.098
BindingDB Entry DOI: 10.7270/Q28P60NS
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50313459
PNG
((Z)-4-oxo-4-(p-tolylamino)but-2-enoic acid | CHEMB...)
Show SMILES Cc1ccc(NC(=O)\C=C/C(O)=O)cc1
Show InChI InChI=1S/C11H11NO3/c1-8-2-4-9(5-3-8)12-10(13)6-7-11(14)15/h2-7H,1H3,(H,12,13)(H,14,15)/b7-6-
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CHEMBL
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Article
PubMed
n/an/a 5.30E+4n/an/an/an/an/an/a



Acadia University

Curated by ChEMBL


Assay Description
Inhibition of human NMT expressed in Escherichia coli DH5alpha cells


Bioorg Med Chem Lett 20: 1510-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.098
BindingDB Entry DOI: 10.7270/Q28P60NS
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50313455
PNG
((Z)-methyl 4-oxo-4-(p-tolylamino)but-2-enoate | CH...)
Show SMILES COC(=O)\C=C/C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C12H13NO3/c1-9-3-5-10(6-4-9)13-11(14)7-8-12(15)16-2/h3-8H,1-2H3,(H,13,14)/b8-7-
PDB
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Article
PubMed
n/an/a>1.00E+7n/an/an/an/an/an/a



Acadia University

Curated by ChEMBL


Assay Description
Inhibition of human NMT expressed in Escherichia coli DH5alpha cells


Bioorg Med Chem Lett 20: 1510-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.098
BindingDB Entry DOI: 10.7270/Q28P60NS
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50313452
PNG
((E)-4-oxo-4-(p-tolylamino)but-2-enoic acid | 4-oxo...)
Show SMILES Cc1ccc(NC(=O)\C=C\C(O)=O)cc1
Show InChI InChI=1S/C11H11NO3/c1-8-2-4-9(5-3-8)12-10(13)6-7-11(14)15/h2-7H,1H3,(H,12,13)(H,14,15)/b7-6+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 8.35E+6n/an/an/an/an/an/a



Acadia University

Curated by ChEMBL


Assay Description
Inhibition of human NMT expressed in Escherichia coli DH5alpha cells


Bioorg Med Chem Lett 20: 1510-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.098
BindingDB Entry DOI: 10.7270/Q28P60NS
More data for this
Ligand-Target Pair