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5 similar compounds to monomer 50314669

Compile data set for download or QSAR
Wt: 286.2
BDBM50314668
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Wt: 250.2
BDBM50314663
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Wt: 264.2
BDBM50314666
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Wt: 284.6
BDBM50314667
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Wt: 329.1
BDBM50314672
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50314668,50314663,50314666,50314667,50314672   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Death-associated protein kinase 3


(Homo sapiens (Human))
BDBM50314663
PNG
(2-phenyl-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one...)
Show SMILES O=C1OC(=N\C1=C/c1cccnc1)c1ccccc1
Show InChI InChI=1S/C15H10N2O2/c18-15-13(9-11-5-4-8-16-10-11)17-14(19-15)12-6-2-1-3-7-12/h1-10H/b13-9-
PDB
MMDB

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Article
PubMed
n/an/a 583n/an/an/an/an/an/a



PharmaDesign, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAPK3


Bioorg Med Chem 18: 2728-34 (2010)


Article DOI: 10.1016/j.bmc.2010.02.018
BindingDB Entry DOI: 10.7270/Q2RB74R2
More data for this
Ligand-Target Pair
Death-associated protein kinase 3


(Homo sapiens (Human))
BDBM50314666
PNG
(4-(pyridin-3-ylmethylene)-2-m-tolyloxazol-5(4H)-on...)
Show SMILES Cc1cccc(c1)C1=N\C(=C/c2cccnc2)C(=O)O1
Show InChI InChI=1S/C16H12N2O2/c1-11-4-2-6-13(8-11)15-18-14(16(19)20-15)9-12-5-3-7-17-10-12/h2-10H,1H3/b14-9-
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n/an/a 714n/an/an/an/an/an/a



PharmaDesign, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAPK3


Bioorg Med Chem 18: 2728-34 (2010)


Article DOI: 10.1016/j.bmc.2010.02.018
BindingDB Entry DOI: 10.7270/Q2RB74R2
More data for this
Ligand-Target Pair
Death-associated protein kinase 3


(Homo sapiens (Human))
BDBM50314672
PNG
(2-(3-bromophenyl)-4-(pyridin-3-ylmethylene)oxazol-...)
Show SMILES Brc1cccc(c1)C1=N\C(=C/c2cccnc2)C(=O)O1
Show InChI InChI=1S/C15H9BrN2O2/c16-12-5-1-4-11(8-12)14-18-13(15(19)20-14)7-10-3-2-6-17-9-10/h1-9H/b13-7-
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n/an/a 148n/an/an/an/an/an/a



PharmaDesign, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAPK3


Bioorg Med Chem 18: 2728-34 (2010)


Article DOI: 10.1016/j.bmc.2010.02.018
BindingDB Entry DOI: 10.7270/Q2RB74R2
More data for this
Ligand-Target Pair
Death-associated protein kinase 3


(Homo sapiens (Human))
BDBM50314668
PNG
(2-(3,4-difluorophenyl)-4-(pyridin-3-ylmethylene)ox...)
Show SMILES Fc1ccc(cc1F)C1=N\C(=C/c2cccnc2)C(=O)O1
Show InChI InChI=1S/C15H8F2N2O2/c16-11-4-3-10(7-12(11)17)14-19-13(15(20)21-14)6-9-2-1-5-18-8-9/h1-8H/b13-6-
PDB
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n/an/a 346n/an/an/an/an/an/a



PharmaDesign, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAPK3


Bioorg Med Chem 18: 2728-34 (2010)


Article DOI: 10.1016/j.bmc.2010.02.018
BindingDB Entry DOI: 10.7270/Q2RB74R2
More data for this
Ligand-Target Pair
Death-associated protein kinase 3


(Homo sapiens (Human))
BDBM50314667
PNG
(2-(4-chlorophenyl)-4-(pyridin-3-ylmethylene)oxazol...)
Show SMILES Clc1ccc(cc1)C1=N\C(=C/c2cccnc2)C(=O)O1
Show InChI InChI=1S/C15H9ClN2O2/c16-12-5-3-11(4-6-12)14-18-13(15(19)20-14)8-10-2-1-7-17-9-10/h1-9H/b13-8-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 530n/an/an/an/an/an/a



PharmaDesign, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAPK3


Bioorg Med Chem 18: 2728-34 (2010)


Article DOI: 10.1016/j.bmc.2010.02.018
BindingDB Entry DOI: 10.7270/Q2RB74R2
More data for this
Ligand-Target Pair