BindingDB logo
myBDB logout

14 molecules are shown

Wt: 276.2
BDBM50321672
Wt: 276.2
BDBM50321673
Wt: 291.3
BDBM50321674
Wt: 262.2
BDBM50321676
Wt: 261.2
BDBM50321677
Wt: 276.2
BDBM50321679
Wt: 276.2
BDBM50321680
Wt: 290.3
BDBM50321681
Wt: 290.3
BDBM50321650
Wt: 291.3
BDBM50321651
Wt: 300.3
BDBM50321655
Wt: 272.3
BDBM50321657
Wt: 310.3
BDBM50321662
Wt: 272.3
BDBM50321664

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50321672,50321673,50321674,50321676,50321677,50321679,50321680,50321681,50321650,50321651,50321655,50321657,50321662,50321664   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321672
PNG
(3-(6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-3-yl)a...)
Show SMILES Nc1cccc(c1)-c1cnc2cnc(cn12)-c1cn[nH]c1
Show InChI InChI=1S/C15H12N6/c16-12-3-1-2-10(4-12)14-7-18-15-8-17-13(9-21(14)15)11-5-19-20-6-11/h1-9H,16H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM50321651
PNG
((4-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)...)
Show SMILES OCc1ccc(cc1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C16H13N5O/c22-10-11-1-3-12(4-2-11)14-9-21-15(13-5-19-20-6-13)7-18-16(21)8-17-14/h1-9,22H,10H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of ABL1 by Z-lite assay


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321650
PNG
((4-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)...)
Show SMILES NCc1ccc(cc1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C16H14N6/c17-5-11-1-3-12(4-2-11)14-10-22-15(13-6-20-21-7-13)8-19-16(22)9-18-14/h1-4,6-10H,5,17H2,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321676
PNG
(3-(1H-pyrazol-4-yl)-6-(pyridin-4-yl)imidazo[1,2-a]...)
Show SMILES c1n[nH]cc1-c1cnc2cnc(cn12)-c1ccncc1
Show InChI InChI=1S/C14H10N6/c1-3-15-4-2-10(1)12-9-20-13(11-5-18-19-6-11)7-17-14(20)8-16-12/h1-9H,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321651
PNG
((4-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)...)
Show SMILES OCc1ccc(cc1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C16H13N5O/c22-10-11-1-3-12(4-2-11)14-9-21-15(13-5-19-20-6-13)7-18-16(21)8-17-14/h1-9,22H,10H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.90E+4n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321677
PNG
(6-phenyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazine...)
Show SMILES c1n[nH]cc1-c1cnc2cnc(cn12)-c1ccccc1
Show InChI InChI=1S/C15H11N5/c1-2-4-11(5-3-1)13-10-20-14(12-6-18-19-7-12)8-17-15(20)9-16-13/h1-10H,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321680
PNG
(3-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)a...)
Show SMILES Nc1cccc(c1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C15H12N6/c16-12-3-1-2-10(4-12)13-9-21-14(11-5-19-20-6-11)7-18-15(21)8-17-13/h1-9H,16H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321681
PNG
((3-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)...)
Show SMILES NCc1cccc(c1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C16H14N6/c17-5-11-2-1-3-12(4-11)14-10-22-15(13-6-20-21-7-13)8-19-16(22)9-18-14/h1-4,6-10H,5,17H2,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321664
PNG
(3-phenyl-6-(pyridin-3-yl)imidazo[1,2-a]pyrazine | ...)
Show SMILES c1nc2cnc(cn2c1-c1ccccc1)-c1cccnc1
Show InChI InChI=1S/C17H12N4/c1-2-5-13(6-3-1)16-10-20-17-11-19-15(12-21(16)17)14-7-4-8-18-9-14/h1-12H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.39E+5n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321657
PNG
(3-phenyl-6-(pyridin-4-yl)imidazo[1,2-a]pyrazine | ...)
Show SMILES c1nc2cnc(cn2c1-c1ccccc1)-c1ccncc1
Show InChI InChI=1S/C17H12N4/c1-2-4-14(5-3-1)16-10-20-17-11-19-15(12-21(16)17)13-6-8-18-9-7-13/h1-12H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.20E+4n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321662
PNG
(6-(1H-indol-3-yl)-3-phenylimidazo[1,2-a]pyrazine |...)
Show SMILES c1nc2cnc(cn2c1-c1ccccc1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H14N4/c1-2-6-14(7-3-1)19-11-23-20-12-22-18(13-24(19)20)16-10-21-17-9-5-4-8-15(16)17/h1-13,21H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321655
PNG
(3-(1H-indol-3-yl)-6-(1H-pyrazol-4-yl)imidazo[1,2-a...)
Show SMILES c1n[nH]cc1-c1cn2c(cnc2cn1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C17H12N6/c1-2-4-14-12(3-1)13(7-18-14)16-8-20-17-9-19-15(10-23(16)17)11-5-21-22-6-11/h1-10,18H,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a 6.50E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321673
PNG
(4-(6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-3-yl)a...)
Show SMILES Nc1ccc(cc1)-c1cnc2cnc(cn12)-c1cn[nH]c1
Show InChI InChI=1S/C15H12N6/c16-12-3-1-10(2-4-12)14-7-18-15-8-17-13(9-21(14)15)11-5-19-20-6-11/h1-9H,16H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321674
PNG
((4-(6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-3-yl)...)
Show SMILES OCc1ccc(cc1)-c1cnc2cnc(cn12)-c1cn[nH]c1
Show InChI InChI=1S/C16H13N5O/c22-10-11-1-3-12(4-2-11)15-7-18-16-8-17-14(9-21(15)16)13-5-19-20-6-13/h1-9,22H,10H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.60E+4n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Serine/threonine-protein kinase CHK2


(Homo sapiens (Human))
BDBM50321655
PNG
(3-(1H-indol-3-yl)-6-(1H-pyrazol-4-yl)imidazo[1,2-a...)
Show SMILES c1n[nH]cc1-c1cn2c(cnc2cn1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C17H12N6/c1-2-4-14-12(3-1)13(7-18-14)16-8-20-17-9-19-15(10-23(16)17)11-5-21-22-6-11/h1-10,18H,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK2 by DELFIA assay


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase CHK2


(Homo sapiens (Human))
BDBM50321650
PNG
((4-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)...)
Show SMILES NCc1ccc(cc1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C16H14N6/c17-5-11-1-3-12(4-2-11)14-10-22-15(13-6-20-21-7-13)8-19-16(22)9-18-14/h1-4,6-10H,5,17H2,(H,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK2 by DELFIA assay


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase CHK2


(Homo sapiens (Human))
BDBM50321651
PNG
((4-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)...)
Show SMILES OCc1ccc(cc1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C16H13N5O/c22-10-11-1-3-12(4-2-11)14-9-21-15(13-5-19-20-6-13)7-18-16(21)8-17-14/h1-9,22H,10H2,(H,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK2 by DELFIA assay


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3 beta


(Homo sapiens (human))
BDBM50321657
PNG
(3-phenyl-6-(pyridin-4-yl)imidazo[1,2-a]pyrazine | ...)
Show SMILES c1nc2cnc(cn2c1-c1ccccc1)-c1ccncc1
Show InChI InChI=1S/C17H12N4/c1-2-4-14(5-3-1)16-10-20-17-11-19-15(12-21(16)17)13-6-8-18-9-7-13/h1-12H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of GSK3-beta at 10 uM by mobility shift assay


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3 beta


(Homo sapiens (human))
BDBM50321655
PNG
(3-(1H-indol-3-yl)-6-(1H-pyrazol-4-yl)imidazo[1,2-a...)
Show SMILES c1n[nH]cc1-c1cn2c(cnc2cn1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C17H12N6/c1-2-4-14-12(3-1)13(7-18-14)16-8-20-17-9-19-15(10-23(16)17)11-5-21-22-6-11/h1-10,18H,(H,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 5.90E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of GSK3-beta at 10 uM by mobility shift assay


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM50321650
PNG
((4-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)...)
Show SMILES NCc1ccc(cc1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C16H14N6/c17-5-11-1-3-12(4-2-11)14-10-22-15(13-6-20-21-7-13)8-19-16(22)9-18-14/h1-4,6-10H,5,17H2,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of ABL1 by Z-lite assay


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens)
BDBM50321679
PNG
(4-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)a...)
Show SMILES Nc1ccc(cc1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
Show InChI InChI=1S/C15H12N6/c16-12-3-1-10(2-4-12)13-9-21-14(11-5-19-20-6-11)7-18-15(21)8-17-13/h1-9H,16H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of CHK1 by DELFIA


Bioorg Med Chem Lett 20: 4045-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.096
BindingDB Entry DOI: 10.7270/Q2MP5487
More data for this
Ligand-Target Pair
3D
3D Structure (docked)