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8 similar compounds to monomer 50440291

Wt: 245.3
BDBM50324526
Wt: 274.3
BDBM50324530
Wt: 285.3
BDBM50440289
Purchase
Wt: 259.3
BDBM50440290
Wt: 287.3
BDBM50440292
Wt: 341.4
BDBM50440286
Wt: 327.4
BDBM50440287
Wt: 313.4
BDBM50440288

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 50324526,50324530,50440289,50440290,50440292,50440286,50440287,50440288   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50324526
PNG
(3-(N-Hydroxy-7-methyloctanamido)propanoic acid | C...)
Show SMILES CC(C)CCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C12H23NO4/c1-10(2)6-4-3-5-7-11(14)13(17)9-8-12(15)16/h10,17H,3-9H2,1-2H3,(H,15,16)
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n/an/a 1.20E+5n/an/an/an/an/an/a



Nagoya City University

Curated by ChEMBL


Assay Description
Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay


J Med Chem 53: 5629-38 (2010)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50440292
PNG
(CHEMBL2424809)
Show SMILES CC(C)CCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C15H29NO4/c1-13(2)9-7-5-3-4-6-8-10-14(17)16(20)12-11-15(18)19/h13,20H,3-12H2,1-2H3,(H,18,19)
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n/an/a 9.20E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C (KDM4C)


(Homo sapiens (Human))
BDBM50324530
PNG
(CHEMBL1215590 | tert-Butyl 3-({Hydroxy[9-(methylam...)
Show SMILES CNCCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C13H26N2O4/c1-14-10-7-5-3-2-4-6-8-12(16)15(19)11-9-13(17)18/h14,19H,2-11H2,1H3,(H,17,18)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Nagoya City University

Curated by ChEMBL


Assay Description
Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay


J Med Chem 53: 5629-38 (2010)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C (KDM4C)


(Homo sapiens (Human))
BDBM50324526
PNG
(3-(N-Hydroxy-7-methyloctanamido)propanoic acid | C...)
Show SMILES CC(C)CCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C12H23NO4/c1-10(2)6-4-3-5-7-11(14)13(17)9-8-12(15)16/h10,17H,3-9H2,1-2H3,(H,15,16)
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n/an/a 7.40E+4n/an/an/an/an/an/a



Nagoya City University

Curated by ChEMBL


Assay Description
Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay


J Med Chem 53: 5629-38 (2010)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 6A (KDM6A)


(Homo sapiens (Human))
BDBM50440286
PNG
(CHEMBL2424815)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCCC1
Show InChI InChI=1S/C19H35NO4/c21-18(20(24)16-15-19(22)23)14-10-4-2-1-3-7-11-17-12-8-5-6-9-13-17/h17,24H,1-16H2,(H,22,23)
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Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant KDM6A after 1 hr


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 6A (KDM6A)


(Homo sapiens (Human))
BDBM50440287
PNG
(CHEMBL2424814)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCC1
Show InChI InChI=1S/C18H33NO4/c20-17(19(23)15-14-18(21)22)13-9-4-2-1-3-6-10-16-11-7-5-8-12-16/h16,23H,1-15H2,(H,21,22)
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Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant KDM6A after 1 hr


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 6A (KDM6A)


(Homo sapiens (Human))
BDBM50440288
PNG
(CHEMBL2424813)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCC1
Show InChI InChI=1S/C17H31NO4/c19-16(18(22)14-13-17(20)21)12-6-4-2-1-3-5-9-15-10-7-8-11-15/h15,22H,1-14H2,(H,20,21)
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Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant KDM6A after 1 hr


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 6A (KDM6A)


(Homo sapiens (Human))
BDBM50440289
PNG
(CHEMBL2424812)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CC1
Show InChI InChI=1S/C15H27NO4/c17-14(16(20)12-11-15(18)19)8-6-4-2-1-3-5-7-13-9-10-13/h13,20H,1-12H2,(H,18,19)
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Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant KDM6A after 1 hr


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 6A (KDM6A)


(Homo sapiens (Human))
BDBM50440290
PNG
(CHEMBL2424811)
Show SMILES CCCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C13H25NO4/c1-2-3-4-5-6-7-8-9-12(15)14(18)11-10-13(16)17/h18H,2-11H2,1H3,(H,16,17)
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Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant KDM6A after 1 hr


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 6A (KDM6A)


(Homo sapiens (Human))
BDBM50440292
PNG
(CHEMBL2424809)
Show SMILES CC(C)CCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C15H29NO4/c1-13(2)9-7-5-3-4-6-8-10-14(17)16(20)12-11-15(18)19/h13,20H,3-12H2,1-2H3,(H,18,19)
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Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant KDM6A after 1 hr


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 2A


(Homo sapiens)
BDBM50440286
PNG
(CHEMBL2424815)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCCC1
Show InChI InChI=1S/C19H35NO4/c21-18(20(24)16-15-19(22)23)14-10-4-2-1-3-7-11-17-12-8-5-6-9-13-17/h17,24H,1-16H2,(H,22,23)
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n/an/a 1.50E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM2A (unknown origin)


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 2A


(Homo sapiens)
BDBM50440287
PNG
(CHEMBL2424814)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCC1
Show InChI InChI=1S/C18H33NO4/c20-17(19(23)15-14-18(21)22)13-9-4-2-1-3-6-10-16-11-7-5-8-12-16/h16,23H,1-15H2,(H,21,22)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM2A (unknown origin)


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 2A


(Homo sapiens)
BDBM50440288
PNG
(CHEMBL2424813)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCC1
Show InChI InChI=1S/C17H31NO4/c19-16(18(22)14-13-17(20)21)12-6-4-2-1-3-5-9-15-10-7-8-11-15/h15,22H,1-14H2,(H,20,21)
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n/an/a 1.60E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM2A (unknown origin)


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 2A


(Homo sapiens)
BDBM50440289
PNG
(CHEMBL2424812)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CC1
Show InChI InChI=1S/C15H27NO4/c17-14(16(20)12-11-15(18)19)8-6-4-2-1-3-5-7-13-9-10-13/h13,20H,1-12H2,(H,18,19)
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n/an/a 6.80E+3n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM2A (unknown origin)


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 2A


(Homo sapiens)
BDBM50440290
PNG
(CHEMBL2424811)
Show SMILES CCCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C13H25NO4/c1-2-3-4-5-6-7-8-9-12(15)14(18)11-10-13(16)17/h18H,2-11H2,1H3,(H,16,17)
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n/an/a 9.60E+3n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM2A (unknown origin)


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 2A


(Homo sapiens)
BDBM50440292
PNG
(CHEMBL2424809)
Show SMILES CC(C)CCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C15H29NO4/c1-13(2)9-7-5-3-4-6-8-10-14(17)16(20)12-11-15(18)19/h13,20H,3-12H2,1-2H3,(H,18,19)
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n/an/a 8.10E+3n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM2A (unknown origin)


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Histone demethylase JARID1A


(Homo sapiens (Human))
BDBM50440286
PNG
(CHEMBL2424815)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCCC1
Show InChI InChI=1S/C19H35NO4/c21-18(20(24)16-15-19(22)23)14-10-4-2-1-3-7-11-17-12-8-5-6-9-13-17/h17,24H,1-16H2,(H,22,23)
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n/an/a 5.50E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM5A (unknown origin) using H3K4me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Histone demethylase JARID1A


(Homo sapiens (Human))
BDBM50440287
PNG
(CHEMBL2424814)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCC1
Show InChI InChI=1S/C18H33NO4/c20-17(19(23)15-14-18(21)22)13-9-4-2-1-3-6-10-16-11-7-5-8-12-16/h16,23H,1-15H2,(H,21,22)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM5A (unknown origin) using H3K4me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Histone demethylase JARID1A


(Homo sapiens (Human))
BDBM50440288
PNG
(CHEMBL2424813)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCC1
Show InChI InChI=1S/C17H31NO4/c19-16(18(22)14-13-17(20)21)12-6-4-2-1-3-5-9-15-10-7-8-11-15/h15,22H,1-14H2,(H,20,21)
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n/an/a 3.50E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM5A (unknown origin) using H3K4me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Histone demethylase JARID1A


(Homo sapiens (Human))
BDBM50440289
PNG
(CHEMBL2424812)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CC1
Show InChI InChI=1S/C15H27NO4/c17-14(16(20)12-11-15(18)19)8-6-4-2-1-3-5-7-13-9-10-13/h13,20H,1-12H2,(H,18,19)
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n/an/a 5.50E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM5A (unknown origin) using H3K4me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Histone demethylase JARID1A


(Homo sapiens (Human))
BDBM50440290
PNG
(CHEMBL2424811)
Show SMILES CCCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C13H25NO4/c1-2-3-4-5-6-7-8-9-12(15)14(18)11-10-13(16)17/h18H,2-11H2,1H3,(H,16,17)
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n/an/a 6.40E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM5A (unknown origin) using H3K4me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Histone demethylase JARID1A


(Homo sapiens (Human))
BDBM50440292
PNG
(CHEMBL2424809)
Show SMILES CC(C)CCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C15H29NO4/c1-13(2)9-7-5-3-4-6-8-10-14(17)16(20)12-11-15(18)19/h13,20H,3-12H2,1-2H3,(H,18,19)
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n/an/a 1.10E+5n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM5A (unknown origin) using H3K4me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C (KDM4C)


(Homo sapiens (Human))
BDBM50440286
PNG
(CHEMBL2424815)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCCC1
Show InChI InChI=1S/C19H35NO4/c21-18(20(24)16-15-19(22)23)14-10-4-2-1-3-7-11-17-12-8-5-6-9-13-17/h17,24H,1-16H2,(H,22,23)
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n/an/a>1.20E+5n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4C (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C (KDM4C)


(Homo sapiens (Human))
BDBM50440287
PNG
(CHEMBL2424814)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCC1
Show InChI InChI=1S/C18H33NO4/c20-17(19(23)15-14-18(21)22)13-9-4-2-1-3-6-10-16-11-7-5-8-12-16/h16,23H,1-15H2,(H,21,22)
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n/an/a 8.10E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4C (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C (KDM4C)


(Homo sapiens (Human))
BDBM50440288
PNG
(CHEMBL2424813)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCC1
Show InChI InChI=1S/C17H31NO4/c19-16(18(22)14-13-17(20)21)12-6-4-2-1-3-5-9-15-10-7-8-11-15/h15,22H,1-14H2,(H,20,21)
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n/an/a 7.80E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4C (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C (KDM4C)


(Homo sapiens (Human))
BDBM50440289
PNG
(CHEMBL2424812)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CC1
Show InChI InChI=1S/C15H27NO4/c17-14(16(20)12-11-15(18)19)8-6-4-2-1-3-5-7-13-9-10-13/h13,20H,1-12H2,(H,18,19)
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n/an/a 8.30E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4C (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C (KDM4C)


(Homo sapiens (Human))
BDBM50440290
PNG
(CHEMBL2424811)
Show SMILES CCCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C13H25NO4/c1-2-3-4-5-6-7-8-9-12(15)14(18)11-10-13(16)17/h18H,2-11H2,1H3,(H,16,17)
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n/an/a 3.20E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4C (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C (KDM4C)


(Homo sapiens (Human))
BDBM50440292
PNG
(CHEMBL2424809)
Show SMILES CC(C)CCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C15H29NO4/c1-13(2)9-7-5-3-4-6-8-10-14(17)16(20)12-11-15(18)19/h13,20H,3-12H2,1-2H3,(H,18,19)
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n/an/a 5.50E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4C (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50440286
PNG
(CHEMBL2424815)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCCC1
Show InChI InChI=1S/C19H35NO4/c21-18(20(24)16-15-19(22)23)14-10-4-2-1-3-7-11-17-12-8-5-6-9-13-17/h17,24H,1-16H2,(H,22,23)
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n/an/a 9.90E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50440287
PNG
(CHEMBL2424814)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCCC1
Show InChI InChI=1S/C18H33NO4/c20-17(19(23)15-14-18(21)22)13-9-4-2-1-3-6-10-16-11-7-5-8-12-16/h16,23H,1-15H2,(H,21,22)
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n/an/a>1.20E+5n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50440288
PNG
(CHEMBL2424813)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CCCC1
Show InChI InChI=1S/C17H31NO4/c19-16(18(22)14-13-17(20)21)12-6-4-2-1-3-5-9-15-10-7-8-11-15/h15,22H,1-14H2,(H,20,21)
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n/an/a>1.20E+5n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50440289
PNG
(CHEMBL2424812)
Show SMILES ON(CCC(O)=O)C(=O)CCCCCCCCC1CC1
Show InChI InChI=1S/C15H27NO4/c17-14(16(20)12-11-15(18)19)8-6-4-2-1-3-5-7-13-9-10-13/h13,20H,1-12H2,(H,18,19)
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n/an/a>1.20E+5n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50440290
PNG
(CHEMBL2424811)
Show SMILES CCCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C13H25NO4/c1-2-3-4-5-6-7-8-9-12(15)14(18)11-10-13(16)17/h18H,2-11H2,1H3,(H,16,17)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay


J Med Chem 56: 7222-31 (2013)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50324530
PNG
(CHEMBL1215590 | tert-Butyl 3-({Hydroxy[9-(methylam...)
Show SMILES CNCCCCCCCCC(=O)N(O)CCC(O)=O
Show InChI InChI=1S/C13H26N2O4/c1-14-10-7-5-3-2-4-6-8-12(16)15(19)11-9-13(17)18/h14,19H,2-11H2,1H3,(H,17,18)
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n/an/a 4.40E+3n/an/an/an/an/an/a



Nagoya City University

Curated by ChEMBL


Assay Description
Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay


J Med Chem 53: 5629-38 (2010)

More data for this
Ligand-Target Pair