BindingDB logo
myBDB logout

44 similar compounds to monomer 50375963

Compile data set for download or QSAR
Wt: 541.6
BDBM50375934
Wt: 567.5
BDBM50375935
Wt: 529.6
BDBM50375937
Wt: 527.6
BDBM50375940
Wt: 527.6
BDBM50375941
Wt: 527.6
BDBM50375942
Wt: 527.6
BDBM50375943
Wt: 568.4
BDBM50375944
Wt: 534.0
BDBM50375945
Wt: 534.0
BDBM50375946
Wt: 534.0
BDBM50375947
Wt: 517.5
BDBM50375948
Wt: 517.5
BDBM50375949
Wt: 499.5
BDBM50375950
Wt: 541.6
BDBM50375951
Displayed 1 to 15 (of 44 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 50375934,50375935,50375937,50375940,50375941,50375942,50375943,50375944,50375945,50375946,50375947,50375948,50375949,50375950,50375951   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375934
PNG
(CHEMBL261337)
Show SMILES CC(=O)c1ccc(cc1)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H32FN5O3/c1-22(38)23-9-12-25(13-10-23)36-18-16-35(17-19-36)15-5-8-30(39)33-21-29-34-28-14-11-24(32)20-27(28)31(40)37(29)26-6-3-2-4-7-26/h2-4,6-7,9-14,20H,5,8,15-19,21H2,1H3,(H,33,39)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 590n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375946
PNG
(CHEMBL260970)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3cccc(Cl)c3)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H29ClFN5O2/c30-21-6-4-9-24(18-21)35-16-14-34(15-17-35)13-5-10-28(37)32-20-27-33-26-12-11-22(31)19-25(26)29(38)36(27)23-7-2-1-3-8-23/h1-4,6-9,11-12,18-19H,5,10,13-17,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375937
PNG
(CHEMBL259236)
Show SMILES COc1ccc(cc1)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C30H32FN5O3/c1-39-25-12-10-23(11-13-25)35-18-16-34(17-19-35)15-5-8-29(37)32-21-28-33-27-14-9-22(31)20-26(27)30(38)36(28)24-6-3-2-4-7-24/h2-4,6-7,9-14,20H,5,8,15-19,21H2,1H3,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 350n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375940
PNG
(CHEMBL411104)
Show SMILES Cc1ccc(cc1C)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H34FN5O2/c1-22-10-12-26(19-23(22)2)36-17-15-35(16-18-36)14-6-9-30(38)33-21-29-34-28-13-11-24(32)20-27(28)31(39)37(29)25-7-4-3-5-8-25/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375941
PNG
(CHEMBL261149)
Show SMILES Cc1ccc(C)c(c1)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H34FN5O2/c1-22-10-11-23(2)28(19-22)36-17-15-35(16-18-36)14-6-9-30(38)33-21-29-34-27-13-12-24(32)20-26(27)31(39)37(29)25-7-4-3-5-8-25/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375942
PNG
(CHEMBL261433)
Show SMILES Cc1ccc(N2CCN(CCCC(=O)NCc3nc4ccc(F)cc4c(=O)n3-c3ccccc3)CC2)c(C)c1
Show InChI InChI=1S/C31H34FN5O2/c1-22-10-13-28(23(2)19-22)36-17-15-35(16-18-36)14-6-9-30(38)33-21-29-34-27-12-11-24(32)20-26(27)31(39)37(29)25-7-4-3-5-8-25/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 620n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375943
PNG
(CHEMBL261434)
Show SMILES Cc1cccc(N2CCN(CCCC(=O)NCc3nc4ccc(F)cc4c(=O)n3-c3ccccc3)CC2)c1C
Show InChI InChI=1S/C31H34FN5O2/c1-22-8-6-11-28(23(22)2)36-18-16-35(17-19-36)15-7-12-30(38)33-21-29-34-27-14-13-24(32)20-26(27)31(39)37(29)25-9-4-3-5-10-25/h3-6,8-11,13-14,20H,7,12,15-19,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 55n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375944
PNG
(CHEMBL407966)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccc(Cl)c(Cl)c3)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H28Cl2FN5O2/c30-24-10-9-22(18-25(24)31)36-15-13-35(14-16-36)12-4-7-28(38)33-19-27-34-26-11-8-20(32)17-23(26)29(39)37(27)21-5-2-1-3-6-21/h1-3,5-6,8-11,17-18H,4,7,12-16,19H2,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 270n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375945
PNG
(CHEMBL260969)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccc(Cl)cc3)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H29ClFN5O2/c30-21-8-11-23(12-9-21)35-17-15-34(16-18-35)14-4-7-28(37)32-20-27-33-26-13-10-22(31)19-25(26)29(38)36(27)24-5-2-1-3-6-24/h1-3,5-6,8-13,19H,4,7,14-18,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375946
PNG
(CHEMBL260970)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3cccc(Cl)c3)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H29ClFN5O2/c30-21-6-4-9-24(18-21)35-16-14-34(15-17-35)13-5-10-28(37)32-20-27-33-26-12-11-22(31)19-25(26)29(38)36(27)23-7-2-1-3-8-23/h1-4,6-9,11-12,18-19H,5,10,13-17,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375947
PNG
(CHEMBL405892)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccccc3Cl)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H29ClFN5O2/c30-24-9-4-5-10-26(24)35-17-15-34(16-18-35)14-6-11-28(37)32-20-27-33-25-13-12-21(31)19-23(25)29(38)36(27)22-7-2-1-3-8-22/h1-5,7-10,12-13,19H,6,11,14-18,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375948
PNG
(CHEMBL260648)
Show SMILES Fc1ccc(cc1)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C29H29F2N5O2/c30-21-8-11-23(12-9-21)35-17-15-34(16-18-35)14-4-7-28(37)32-20-27-33-26-13-10-22(31)19-25(26)29(38)36(27)24-5-2-1-3-6-24/h1-3,5-6,8-13,19H,4,7,14-18,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375949
PNG
(CHEMBL411442)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccccc3F)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H29F2N5O2/c30-21-12-13-25-23(19-21)29(38)36(22-7-2-1-3-8-22)27(33-25)20-32-28(37)11-6-14-34-15-17-35(18-16-34)26-10-5-4-9-24(26)31/h1-5,7-10,12-13,19H,6,11,14-18,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375950
PNG
(CHEMBL261572)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccccc3)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H30FN5O2/c30-22-13-14-26-25(20-22)29(37)35(24-10-5-2-6-11-24)27(32-26)21-31-28(36)12-7-15-33-16-18-34(19-17-33)23-8-3-1-4-9-23/h1-6,8-11,13-14,20H,7,12,15-19,21H2,(H,31,36)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 470n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375951
PNG
(CHEMBL261018)
Show SMILES CC(=O)c1ccc(cc1)N1CCN(CCCC(=O)NCc2nc3cc(F)ccc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H32FN5O3/c1-22(38)23-9-12-25(13-10-23)36-18-16-35(17-19-36)15-5-8-30(39)33-21-29-34-28-20-24(32)11-14-27(28)31(40)37(29)26-6-3-2-4-7-26/h2-4,6-7,9-14,20H,5,8,15-19,21H2,1H3,(H,33,39)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 680n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50375943
PNG
(CHEMBL261434)
Show SMILES Cc1cccc(N2CCN(CCCC(=O)NCc3nc4ccc(F)cc4c(=O)n3-c3ccccc3)CC2)c1C
Show InChI InChI=1S/C31H34FN5O2/c1-22-8-6-11-28(23(22)2)36-18-16-35(17-19-36)15-7-12-30(38)33-21-29-34-27-14-13-24(32)20-26(27)31(39)37(29)25-9-4-3-5-10-25/h3-6,8-11,13-14,20H,7,12,15-19,21H2,1-2H3,(H,33,38)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Binding affinity at 5HT1A receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50375943
PNG
(CHEMBL261434)
Show SMILES Cc1cccc(N2CCN(CCCC(=O)NCc3nc4ccc(F)cc4c(=O)n3-c3ccccc3)CC2)c1C
Show InChI InChI=1S/C31H34FN5O2/c1-22-8-6-11-28(23(22)2)36-18-16-35(17-19-36)15-7-12-30(38)33-21-29-34-27-14-13-24(32)20-26(27)31(39)37(29)25-9-4-3-5-10-25/h3-6,8-11,13-14,20H,7,12,15-19,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Binding affinity at 5HT2A receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50375943
PNG
(CHEMBL261434)
Show SMILES Cc1cccc(N2CCN(CCCC(=O)NCc3nc4ccc(F)cc4c(=O)n3-c3ccccc3)CC2)c1C
Show InChI InChI=1S/C31H34FN5O2/c1-22-8-6-11-28(23(22)2)36-18-16-35(17-19-36)15-7-12-30(38)33-21-29-34-27-14-13-24(32)20-26(27)31(39)37(29)25-9-4-3-5-10-25/h3-6,8-11,13-14,20H,7,12,15-19,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 80n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Binding affinity at 5HT2C receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50375943
PNG
(CHEMBL261434)
Show SMILES Cc1cccc(N2CCN(CCCC(=O)NCc3nc4ccc(F)cc4c(=O)n3-c3ccccc3)CC2)c1C
Show InChI InChI=1S/C31H34FN5O2/c1-22-8-6-11-28(23(22)2)36-18-16-35(17-19-36)15-7-12-30(38)33-21-29-34-27-14-13-24(32)20-26(27)31(39)37(29)25-9-4-3-5-10-25/h3-6,8-11,13-14,20H,7,12,15-19,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Binding affinity at dopamine D2 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375951
PNG
(CHEMBL261018)
Show SMILES CC(=O)c1ccc(cc1)N1CCN(CCCC(=O)NCc2nc3cc(F)ccc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H32FN5O3/c1-22(38)23-9-12-25(13-10-23)36-18-16-35(17-19-36)15-5-8-30(39)33-21-29-34-28-20-24(32)11-14-27(28)31(40)37(29)26-6-3-2-4-7-26/h2-4,6-7,9-14,20H,5,8,15-19,21H2,1H3,(H,33,39)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 681n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375950
PNG
(CHEMBL261572)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccccc3)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H30FN5O2/c30-22-13-14-26-25(20-22)29(37)35(24-10-5-2-6-11-24)27(32-26)21-31-28(36)12-7-15-33-16-18-34(19-17-33)23-8-3-1-4-9-23/h1-6,8-11,13-14,20H,7,12,15-19,21H2,(H,31,36)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 470n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375949
PNG
(CHEMBL411442)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccccc3F)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H29F2N5O2/c30-21-12-13-25-23(19-21)29(38)36(22-7-2-1-3-8-22)27(33-25)20-32-28(37)11-6-14-34-15-17-35(18-16-34)26-10-5-4-9-24(26)31/h1-5,7-10,12-13,19H,6,11,14-18,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375948
PNG
(CHEMBL260648)
Show SMILES Fc1ccc(cc1)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C29H29F2N5O2/c30-21-8-11-23(12-9-21)35-17-15-34(16-18-35)14-4-7-28(37)32-20-27-33-26-13-10-22(31)19-25(26)29(38)36(27)24-5-2-1-3-6-24/h1-3,5-6,8-13,19H,4,7,14-18,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375947
PNG
(CHEMBL405892)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccccc3Cl)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H29ClFN5O2/c30-24-9-4-5-10-26(24)35-17-15-34(16-18-35)14-6-11-28(37)32-20-27-33-25-13-12-21(31)19-23(25)29(38)36(27)22-7-2-1-3-8-22/h1-5,7-10,12-13,19H,6,11,14-18,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375945
PNG
(CHEMBL260969)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccc(Cl)cc3)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H29ClFN5O2/c30-21-8-11-23(12-9-21)35-17-15-34(16-18-35)14-4-7-28(37)32-20-27-33-26-13-10-22(31)19-25(26)29(38)36(27)24-5-2-1-3-6-24/h1-3,5-6,8-13,19H,4,7,14-18,20H2,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375944
PNG
(CHEMBL407966)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3ccc(Cl)c(Cl)c3)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C29H28Cl2FN5O2/c30-24-10-9-22(18-25(24)31)36-15-13-35(14-16-36)12-4-7-28(38)33-19-27-34-26-11-8-20(32)17-23(26)29(39)37(27)21-5-2-1-3-6-21/h1-3,5-6,8-11,17-18H,4,7,12-16,19H2,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 270n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375943
PNG
(CHEMBL261434)
Show SMILES Cc1cccc(N2CCN(CCCC(=O)NCc3nc4ccc(F)cc4c(=O)n3-c3ccccc3)CC2)c1C
Show InChI InChI=1S/C31H34FN5O2/c1-22-8-6-11-28(23(22)2)36-18-16-35(17-19-36)15-7-12-30(38)33-21-29-34-27-14-13-24(32)20-26(27)31(39)37(29)25-9-4-3-5-10-25/h3-6,8-11,13-14,20H,7,12,15-19,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 55.0n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375942
PNG
(CHEMBL261433)
Show SMILES Cc1ccc(N2CCN(CCCC(=O)NCc3nc4ccc(F)cc4c(=O)n3-c3ccccc3)CC2)c(C)c1
Show InChI InChI=1S/C31H34FN5O2/c1-22-10-13-28(23(2)19-22)36-17-15-35(16-18-36)14-6-9-30(38)33-21-29-34-27-12-11-24(32)20-26(27)31(39)37(29)25-7-4-3-5-8-25/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 619n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375941
PNG
(CHEMBL261149)
Show SMILES Cc1ccc(C)c(c1)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H34FN5O2/c1-22-10-11-23(2)28(19-22)36-17-15-35(16-18-36)14-6-9-30(38)33-21-29-34-27-13-12-24(32)20-26(27)31(39)37(29)25-7-4-3-5-8-25/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375935
PNG
(CHEMBL260906)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C30H29F4N5O2/c31-22-11-12-26-25(19-22)29(41)39(23-7-2-1-3-8-23)27(36-26)20-35-28(40)10-5-13-37-14-16-38(17-15-37)24-9-4-6-21(18-24)30(32,33)34/h1-4,6-9,11-12,18-19H,5,10,13-17,20H2,(H,35,40)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 74.0n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375940
PNG
(CHEMBL411104)
Show SMILES Cc1ccc(cc1C)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H34FN5O2/c1-22-10-12-26(19-23(22)2)36-17-15-35(16-18-36)14-6-9-30(38)33-21-29-34-28-13-11-24(32)20-27(28)31(39)37(29)25-7-4-3-5-8-25/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3,(H,33,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375937
PNG
(CHEMBL259236)
Show SMILES COc1ccc(cc1)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C30H32FN5O3/c1-39-25-12-10-23(11-13-25)35-18-16-34(17-19-35)15-5-8-29(37)32-21-28-33-27-14-9-22(31)20-26(27)30(38)36(28)24-6-3-2-4-7-24/h2-4,6-7,9-14,20H,5,8,15-19,21H2,1H3,(H,32,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 350n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375934
PNG
(CHEMBL261337)
Show SMILES CC(=O)c1ccc(cc1)N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H32FN5O3/c1-22(38)23-9-12-25(13-10-23)36-18-16-35(17-19-36)15-5-8-30(39)33-21-29-34-28-14-11-24(32)20-27(28)31(40)37(29)26-6-3-2-4-7-26/h2-4,6-7,9-14,20H,5,8,15-19,21H2,1H3,(H,33,39)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 590n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50375935
PNG
(CHEMBL260906)
Show SMILES Fc1ccc2nc(CNC(=O)CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)n(-c3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C30H29F4N5O2/c31-22-11-12-26-25(19-22)29(41)39(23-7-2-1-3-8-23)27(36-26)20-35-28(40)10-5-13-37-14-16-38(17-15-37)24-9-4-6-21(18-24)30(32,33)34/h1-4,6-9,11-12,18-19H,5,10,13-17,20H2,(H,35,40)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 74n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair