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1 similar compounds to monomer 50376831

Compile data set for download or QSAR
Wt: 434.6
BDBM50376830

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376830   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))
BDBM50376830
PNG
(CHEMBL258967)
Show SMILES CCN(C1CCCc2nc(ccc12)-c1c(CC)cccc1CC)c1cccc2ccccc12
Show InChI InChI=1S/C31H34N2/c1-4-22-13-9-14-23(5-2)31(22)28-21-20-26-27(32-28)17-11-19-30(26)33(6-3)29-18-10-15-24-12-7-8-16-25(24)29/h7-10,12-16,18,20-21,30H,4-6,11,17,19H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Johnson& Johnson PRD

Curated by ChEMBL


Assay Description
Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization


Bioorg Med Chem Lett 18: 2544-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.049
BindingDB Entry DOI: 10.7270/Q2JM2BHD
More data for this
Ligand-Target Pair