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1 similar compounds to monomer 50397107

Compile data set for download or QSAR
Wt: 324.3
BDBM50397105

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50397105   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Class I phosphodiesterase B1 (TbrPDEB1)


(Trypanosoma brucei)
BDBM50397105
PNG
(CHEMBL2171661)
Show SMILES COc1ccc(cc1OCc1ccccc1)C1=NNC(=O)C1(C)C
Show InChI InChI=1S/C19H20N2O3/c1-19(2)17(20-21-18(19)22)14-9-10-15(23-3)16(11-14)24-12-13-7-5-4-6-8-13/h4-11H,12H2,1-3H3,(H,21,22)
PDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.30E+3n/an/an/an/an/an/a



VU University Amsterdam

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...


J Med Chem 55: 8745-56 (2012)


Article DOI: 10.1021/jm301059b
BindingDB Entry DOI: 10.7270/Q2SF2X96
More data for this
Ligand-Target Pair