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3 similar compounds to monomer 50429904

Compile data set for download or QSAR
Wt: 247.3
BDBM50406439
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Wt: 275.3
BDBM50406442
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Wt: 261.3
BDBM50406456

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50406439,50406442,50406456   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50406439
PNG
(CHEMBL104311)
Show SMILES NS(=O)(=O)c1ccc(SCCCO)cc1
Show InChI InChI=1S/C9H13NO3S2/c10-15(12,13)9-4-2-8(3-5-9)14-7-1-6-11/h2-5,11H,1,6-7H2,(H2,10,12,13)
PDB
MMDB

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Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against human carbonic anhydrase II using pH stat assay


J Med Chem 34: 3098-105 (1991)


Article DOI: 10.1021/jm00114a020
BindingDB Entry DOI: 10.7270/Q2SJ1MTV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50406456
PNG
(CHEMBL107537)
Show SMILES NS(=O)(=O)c1ccc(SCCCCO)cc1
Show InChI InChI=1S/C10H15NO3S2/c11-16(13,14)10-5-3-9(4-6-10)15-8-2-1-7-12/h3-6,12H,1-2,7-8H2,(H2,11,13,14)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against human carbonic anhydrase II using pH stat assay


J Med Chem 34: 3098-105 (1991)


Article DOI: 10.1021/jm00114a020
BindingDB Entry DOI: 10.7270/Q2SJ1MTV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50406442
PNG
(CHEMBL319239)
Show SMILES NS(=O)(=O)c1ccc(SCCCCCO)cc1
Show InChI InChI=1S/C11H17NO3S2/c12-17(14,15)11-6-4-10(5-7-11)16-9-3-1-2-8-13/h4-7,13H,1-3,8-9H2,(H2,12,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.30n/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against human carbonic anhydrase II using pH stat assay


J Med Chem 34: 3098-105 (1991)


Article DOI: 10.1021/jm00114a020
BindingDB Entry DOI: 10.7270/Q2SJ1MTV
More data for this
Ligand-Target Pair