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11 similar compounds to monomer 50406654

Compile data set for download or QSAR
Wt: 337.4
BDBM50406659
Wt: 373.5
BDBM50406660
Wt: 347.4
BDBM50406661
Wt: 381.5
BDBM50406667
Wt: 319.4
BDBM50406670
Wt: 347.4
BDBM50406673
Wt: 333.4
BDBM50406674
Wt: 305.4
BDBM50406647
Wt: 333.4
BDBM50406648
Wt: 331.4
BDBM50406655
Wt: 347.4
BDBM50406658

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50406659,50406660,50406661,50406667,50406670,50406673,50406674,50406647,50406648,50406655,50406658   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406647
PNG
(CHEMBL81506)
Show SMILES CNC(=O)NCCCOc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C17H27N3O2/c1-18-17(21)19-9-6-12-22-16-8-5-7-15(13-16)14-20-10-3-2-4-11-20/h5,7-8,13H,2-4,6,9-12,14H2,1H3,(H2,18,19,21)
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n/an/an/a 155n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406648
PNG
(CHEMBL82654)
Show SMILES CC(C)NC(=O)NCCCOc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C19H31N3O2/c1-16(2)21-19(23)20-10-7-13-24-18-9-6-8-17(14-18)15-22-11-4-3-5-12-22/h6,8-9,14,16H,3-5,7,10-13,15H2,1-2H3,(H2,20,21,23)
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n/an/an/a 43.6n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406655
PNG
(CHEMBL432167)
Show SMILES O=C(NCCCOc1cccc(CN2CCCCC2)c1)NC1CC1
Show InChI InChI=1S/C19H29N3O2/c23-19(21-17-8-9-17)20-10-5-13-24-18-7-4-6-16(14-18)15-22-11-2-1-3-12-22/h4,6-7,14,17H,1-3,5,8-13,15H2,(H2,20,21,23)
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n/an/an/a 47.9n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406658
PNG
(CHEMBL81750)
Show SMILES CCC(C)NC(=O)NCCCOc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C20H33N3O2/c1-3-17(2)22-20(24)21-11-8-14-25-19-10-7-9-18(15-19)16-23-12-5-4-6-13-23/h7,9-10,15,17H,3-6,8,11-14,16H2,1-2H3,(H2,21,22,24)
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n/an/an/a 95.5n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406659
PNG
(CHEMBL78339)
Show SMILES FCCNC(=O)NCCCOc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C18H28FN3O2/c19-8-10-21-18(23)20-9-5-13-24-17-7-4-6-16(14-17)15-22-11-2-1-3-12-22/h4,6-7,14H,1-3,5,8-13,15H2,(H2,20,21,23)
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n/an/an/a 85.1n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406674
PNG
(CHEMBL82599)
Show SMILES CCCNC(=O)NCCCOc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C19H31N3O2/c1-2-10-20-19(23)21-11-7-14-24-18-9-6-8-17(15-18)16-22-12-4-3-5-13-22/h6,8-9,15H,2-5,7,10-14,16H2,1H3,(H2,20,21,23)
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n/an/an/a 97.7n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406661
PNG
(CHEMBL79974)
Show SMILES CC(C)CNC(=O)NCCCOc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C20H33N3O2/c1-17(2)15-22-20(24)21-10-7-13-25-19-9-6-8-18(14-19)16-23-11-4-3-5-12-23/h6,8-9,14,17H,3-5,7,10-13,15-16H2,1-2H3,(H2,21,22,24)
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n/an/an/a 170n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406667
PNG
(CHEMBL80105)
Show SMILES O=C(NCCCOc1cccc(CN2CCCCC2)c1)NCc1ccccc1
Show InChI InChI=1S/C23H31N3O2/c27-23(25-18-20-9-3-1-4-10-20)24-13-8-16-28-22-12-7-11-21(17-22)19-26-14-5-2-6-15-26/h1,3-4,7,9-12,17H,2,5-6,8,13-16,18-19H2,(H2,24,25,27)
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n/an/an/a 347n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406670
PNG
(DALCOTIDINE)
Show SMILES CCNC(=O)NCCCOc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C18H29N3O2/c1-2-19-18(22)20-10-7-13-23-17-9-6-8-16(14-17)15-21-11-4-3-5-12-21/h6,8-9,14H,2-5,7,10-13,15H2,1H3,(H2,19,20,22)
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n/an/an/a 40.7n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406673
PNG
(CHEMBL78519)
Show SMILES CCCCNC(=O)NCCCOc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C20H33N3O2/c1-2-3-11-21-20(24)22-12-8-15-25-19-10-7-9-18(16-19)17-23-13-5-4-6-14-23/h7,9-10,16H,2-6,8,11-15,17H2,1H3,(H2,21,22,24)
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n/an/an/a 81.3n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406660
PNG
(CHEMBL81545)
Show SMILES O=C(NCCCOc1cccc(CN2CCCCC2)c1)NC1CCCCC1
Show InChI InChI=1S/C22H35N3O2/c26-22(24-20-10-3-1-4-11-20)23-13-8-16-27-21-12-7-9-19(17-21)18-25-14-5-2-6-15-25/h7,9,12,17,20H,1-6,8,10-11,13-16,18H2,(H2,23,24,26)
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n/an/an/a 43.6n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair